Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts (Q79074390)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14500687%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

title

Antagonistic effects of TNF-alpha on TGF-beta signaling through down-regulation of TGF-beta receptor type II in human dermal fibroblasts (English)

1 reference

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19 December 2019

Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts (English)

1 reference

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skin physiological phenomena

12 March 2024

main subject

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12 March 2024

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12 March 2024

author name string

Kenichi Yamane

1

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19 December 2019

Hironobu Ihn

2

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19 December 2019

Yoshihide Asano

3

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19 December 2019

Masatoshi Jinnin

4

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19 December 2019

Kunihiko Tamaki

5

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19 December 2019

language of work or name

English

0 references

publication date

1 October 2003

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full work available at URL

19 December 2019

published in

Journal of Immunology

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19 December 2019

volume

171

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19 December 2019

issue

7

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19 December 2019

page(s)

3855-3862

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Mechanism of activation of the TGF-beta receptor

19 December 2019

cites work

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24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/370341A0

The transforming growth factor-beta family

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Transforming growth factor beta in tissue fibrosis

12 March 2024

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TGF-beta signaling by Smad proteins

12 March 2024

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Signal transduction by members of the transforming growth factor-beta superfamily

12 March 2024

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

12 March 2024

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TGF-beta signal transduction

12 March 2024

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A transcriptional partner for MAD proteins in TGF-beta signalling

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

12 March 2024

9

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter

12 March 2024

10

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

12 March 2024

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The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models

12 March 2024

12

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Tumor necrosis factor-alpha and interferon-gamma suppress the activation of human type I collagen gene expression by transforming growth factor-beta 1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

12 March 2024

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Transcriptional Regulation of the Human α2(I) Collagen Gene

12 March 2024

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Oncostatin M Stimulates Transcription of the Human α2(I) Collagen Gene via the Sp1/Sp3-binding Site

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors

12 March 2024

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Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Smad3 and Smad4 mediate transcriptional activation of the human Smad7 promoter by transforming growth factor beta

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoter

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

12 March 2024

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Co-localization of transforming growth factor beta 2 with alpha 1(I) procollagen mRNA in tissue sections of patients with systemic sclerosis

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts

12 March 2024

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Excess matrix accumulation in scleroderma is caused partly by differential regulation of stromelysin and TIMP-1 synthesis

12 March 2024

35

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1.

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Discordant regulation of transforming growth factor-beta receptors by prostaglandin E2

12 March 2024

37

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Modulation of responses to TGF-beta by 1, 25 dihydroxyvitamin D3 in MG-63 osteoblastic cells: possible involvement of regulation of TGF-beta type II receptor

12 March 2024

38

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Structure and expression of the promoter for the R4/ALK5 human type I transforming growth factor-beta receptor: regulation by TGF-beta

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Differentiation and transforming growth factor-beta receptor down-regulation by collagen-alpha2beta1 integrin interaction is mediated by focal adhesion kinase and its downstream signals in murine osteoblastic cells

12 March 2024

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Control of type II transforming growth factor-beta receptor expression by integrin ligation

12 March 2024

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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Molecular mechanisms of inactivation of TGF-beta receptors during carcinogenesis

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Up-regulated expression of transforming growth factor beta receptors in dermal fibroblasts in skin sections from patients with localized scleroderma

12 March 2024

47

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Role of transforming growth factor beta type II receptor in hepatic fibrosis: studies of human chronic hepatitis C and experimental fibrosis in rats

12 March 2024

48

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Overexpression of transforming growth factor-beta1 and insulin-like growth factor-I in patients with idiopathic hypertrophic cardiomyopathy

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Transforming growth factor-beta receptor and fibronectin expressions in aortic smooth muscle cells in diabetic rats

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

Secretion and binding of transforming growth factor beta by scleroderma and normal dermal fibroblasts.

12 March 2024

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

12 March 2024

The Smad pathway

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3855

12 March 2024

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14500687%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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