Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3β/Snail signaling in renal cell carcinoma (Q86188408)

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24 February 2020

title

Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3β/Snail signaling in renal cell carcinoma (English)

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24 February 2020

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Yu Zhu

1

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Le Xu

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Jianping Zhang

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24 February 2020

Wenping Xu

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Yujun Liu

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Hankun Yin

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Tao Lv

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24 February 2020

Huimin An

8

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Li Liu

9

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Hongyong He

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24 February 2020

Heng Zhang

11

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Jing Liu

12

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Jiejie Xu

13

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Zongming Lin

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publication date

29 March 2013

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24 February 2020

volume

104

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issue

6

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24 February 2020

page(s)

663-671

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AACR Special Conference on Epithelial-Mesenchymal Transition and Cancer Progression and Treatment

24 February 2020

cites work

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12 December 2020

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

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12 December 2020

Hepatitis B virus X protein confers resistance of hepatoma cells to anoikis by up-regulating and activating p21-activated kinase 1

1 reference

12 December 2020

The genetic basis of kidney cancer: implications for management and use of targeted therapeutic approaches

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12 December 2020

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

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12 December 2020

The anti-aging gene KLOTHO is a novel target for epigenetic silencing in human cervical carcinoma

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12 December 2020

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

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12 December 2020

Relevant use of Klotho in FGF19 subfamily signaling system in vivo

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12 December 2020

Klotho converts canonical FGF receptor into a specific receptor for FGF23

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12 December 2020

Hepatitis B virus X protein blunts senescence-like growth arrest of human hepatocellular carcinoma by reducing Notch1 cleavage

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12 December 2020

Klotho: a master regulator of cardiovascular disease?

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12 December 2020

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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12 December 2020

Molecular diagnosis and therapy of kidney cancer

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12 December 2020

Klotho, an anti-senescence related gene, is frequently inactivated through promoter hypermethylation in colorectal cancer.

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12 December 2020

Hepatitis B virus X protein promotes hepatoma cell invasion and metastasis by stabilizing Snail protein

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12 December 2020

Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling

1 reference

12 December 2020

The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy

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12 December 2020

Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice

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12 December 2020

GSK-3: tricks of the trade for a multi-tasking kinase

1 reference

12 December 2020

Hepatitis B virus large surface antigen promotes liver carcinogenesis by activating the Src/PI3K/Akt pathway

1 reference

12 December 2020

The basics of epithelial-mesenchymal transition

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12 December 2020

Klotho inhibits growth and promotes apoptosis in human lung cancer cell line A549.

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12 December 2020

Increased serum levels of basic fibroblast growth factor (bFGF) are associated with progressive lung metastases in advanced renal cell carcinoma patients.

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12 December 2020

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12 December 2020

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12 December 2020

Klotho: an antiaging protein involved in mineral and vitamin D metabolism

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12 December 2020

Regulation of oxidative stress by the anti-aging hormone klotho

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12 December 2020

Klotho is silenced through promoter hypermethylation in gastric cancer.

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12 December 2020

KL1 internal repeat mediates klotho tumor suppressor activities and inhibits bFGF and IGF-I signaling in pancreatic cancer

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12 December 2020

Effects of sialic acid substitutions on recognition by Sambucus nigra agglutinin and Maackia amurensis hemagglutinin

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12 December 2020

Klotho suppresses RIG-I-mediated senescence-associated inflammation.

1 reference

12 December 2020

What can molecular pathology contribute to the management of renal cell carcinoma?

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12 December 2020

Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy.

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12 December 2020

Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility.

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12 December 2020

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

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12 December 2020

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

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12 December 2020

Regulation of fibroblast growth factor-23 signaling by klotho

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12 December 2020

Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho

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12 December 2020

Treatment of metastatic renal cell carcinoma.

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12 December 2020

EMT: when epithelial cells decide to become mesenchymal-like cells

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12 December 2020

Suppression of aging in mice by the hormone Klotho

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12 December 2020

Klotho predicts good clinical outcome in patients with limited-disease small cell lung cancer who received surgery

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12 December 2020

Renal cell carcinoma guideline

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12 December 2020

PI3K/Akt: getting it right matters

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12 December 2020

Expression of Snail and Slug in renal cell carcinoma: E-cadherin repressor Snail is associated with cancer invasion and prognosis

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12 December 2020

Identifiers

DOI

10.1111/CAS.12134

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24 February 2020

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