Orly Alter (Q92970069)

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Israeli-American geneticist, mathematician, and physicist
  • O. Alter
  • Alter, O.
  • Alter, Orly
edit
Language Label Description Also known as
English
Orly Alter
Israeli-American geneticist, mathematician, and physicist
  • O. Alter
  • Alter, O.
  • Alter, Orly

Statements

instance of
human
20 references
stated in
ORCID iD
ORCID iD
0000-0002-0418-1078
retrieved
13 October 2020
subject named as
Orly Alter
reference URL
https://www.aps.org/publications/apsnews/199808/damop.cfm
publisher
American Physical Society
publication date
August 1998
subject named as
Orly Alter
quotation
The DAMOP Thesis Award recognizes doctoral thesis research of outstanding quality and achievement in atomic, molecular or optical physics, and encourages effective written and oral presentation of research results. The other four finalists, and their thesis topics, were Orly Alter (Stanford University), "Impossibility of Determining the Quantum Wavefunction of a Single System and Fundamental Limit to External Force Detection"... (English)
reference URL
https://scholar.google.com/scholar?as_q=&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=&as_publication=Proceedings+of+the+National+Academy+of+Sciences&as_ylo=2000&as_yhi=2000&hl=en
subject named as
Orly Alter
quotation
9th most cited Proceedings of the National Academy of Sciences (PNAS) USA paper of the year 2000 and 56th most cited PNAS paper of all time. (English)
retrieved
26 August 2022
stated in
Google Scholar
stated in
The Lancet
DOI
10.1016/S0140-6736(02)08281-8
publication date
April 2002
subject named as
Nielsen and colleagues
stated in
Physical Review D
DOI
10.1103/PHYSREVD.67.082001
publication date
April 2003
subject named as
Alter and Yamamoto
quotation
The crucial idea of avoiding the influence of the test-mass initial state by monitoring differences of observables... is contained in a paper and book by Alter and Yamamoto... (English)
stated in
Meeting report: the Institute for Genomic Research/Wellcome Trust Conference: Genomes 2004 14-17 April 2004, the Wellcome Trust Conference Centre, the Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
DOI
10.1002/CFG.300
publication date
October 2003
subject named as
Orly Alter (Stanford University, USA)
reference URL
https://archive.siam.org/pdf/news/277.pdf
publisher
Society for Industrial and Applied Mathematics
publication date
November 2004
subject named as
Orly Alter (University of Texas at Austin)
reference URL
https://nap.nationalacademies.org/catalog/11315/mathematics-and-21st-century-biology
publisher
National Academies of Sciences, Engineering, and Medicine
publication date
July 2005
subject named as
Alter et al.
reference URL
https://secureservercdn.net/72.167.241.46/31g.343.myftpupload.com/wp-content/uploads/IMAGE/image35.pdf
publisher
International Linear Algebra Society
publication date
December 2005
subject named as
Orly Alter
reference URL
https://www.eurekalert.org/news-releases/815594
publisher
American Academy of Arts and Sciences
publication date
October 2009
subject named as
Orly Alter
reference URL
https://alterlab.org/in_the_news/Dwivedi_IBS_Bulletin_2010_Feature.pdf
publisher
International Biometric Society
publication date
January 2010
subject named as
Rao with participants of the track on Biotechnology
reference URL
https://facultyopinions.com/article/1728974#tab=abstract
publisher
Faculty Opinions
publication date
February 2010
subject named as
Omberg et al.
reference URL
https://www.eurekalert.org/news-releases/866753
publisher
American Academy of Arts and Sciences
publication date
15 April 2015
subject named as
Orly Alter
reference URL
https://www.nae.edu/File.aspx?id=134900&File.mp3
publisher
National Academy of Engineering
publication date
19 April 2015
subject named as
Orly Alter
reference URL
https://thepathologist.com/inside-the-lab/big-data-hidden-knowledge
title
The Pathologist (English)
publication date
15 June 2015
subject named as
Orly Alter
reference URL
https://physics.cancer.gov/research-funding/utah#investigators
publisher
Physical Sciences in Oncology Network
part of
National Cancer Institute
publication date
September 2015
subject named as
Dr. Orly Alter
quotation
Dr. Orly Alter is a USTAR associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah. Inventor of the "eigengene," she pioneered the matrix and tensor modeling of large-scale molecular biological data, which, as she demonstrated, can be used to correctly predict previously unknown cellular mechanisms. (English)
stated in
APL Bioengineering
reference URL
https://aip-info.org/1XPS-5VDRA-50C9RKAB1F/cr.aspx
publication date
September 2018
subject named as
Orly Alter
stated in
APL Bioengineering
reference URL
https://aip-info.org/1XPS-6A0AU-C5ITTQWO7B/cr.aspx
publication date
2019
subject named as
Orly Alter
reference URL
https://www.eurekalert.org/news-releases/477030
publisher
American Academy of Arts and Sciences
publication date
15 May 2020
subject named as
the team leader Orly Alter, Ph.D., Utah Science, Technology, and Research (USTAR) associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah
stated in
APL Bioengineering
reference URL
https://aip-info.org/1XPS-7KD96-527719389D75CF2AOLGQ4XE7DE4193976FA499/cr.aspx
publication date
2021
subject named as
Orly Alter
image
Orly Alter EurekAlert! 2020.jpg
2,790 × 3,044; 3.29 MB
depicts
Orly Alter
media legend
In her Genomic Signal Processing Lab, Alter develops new mathematical methods that are uniquely suited for personalized medicine. (English)
2 references
imported from Wikimedia project
Wikimedia Commons
retrieved
15 July 2022
reference URL
https://eurekalert.org/news-releases/477030
publisher
American Academy of Arts and Sciences
publication date
2020
Orly Alter EurekAlert! 2015.jpg
4,931 × 3,287; 7.81 MB
depicts
Orly Alter
media legend
In her Genomic Signal Processing Lab, Alter develops new mathematical techniques, inspired by theoretical physics, for finding patterns in data. (English)
2 references
imported from Wikimedia project
Wikimedia Commons
retrieved
24 July 2022
reference URL
https://eurekalert.org/news-releases/866753
publisher
American Academy of Arts and Sciences
publication date
2015
name in native language
אורלי אלטר (Hebrew)
0 references
place of birth
Tel Aviv
0 references
native language
Hebrew
0 references
occupation
professor
title
Utah Science, Technology, and Research (USTAR) associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah (English)
1 reference
stated in
ORCID iD
ORCID iD
0000-0002-0418-1078
inventor
main subject
eigengene
multi-tensor decomposition
8 references
reference URL
https://physics.cancer.gov/research-funding/utah#investigators
publisher
Physical Sciences in Oncology Network
part of
National Cancer Institute
quotation
Dr. Orly Alter is a USTAR associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah. Inventor of the "eigengene"... (English)
Wikimedia import URL
https://en.wiktionary.org/wiki/Citations:eigengene
retrieved
22 July 2022
quotation
2020, O. Alter, ‘‘Discovering Genome-Scale Predictors of Survival and Response to Treatment with Multi-Tensor Decompositions’’ 2020 American Association for Cancer Research (AACR) Virtual Annual Meeting II (June 22–24, 2020); YouTube video: The SVD finds for us patterns that look like genes, which is the "eigengene" concept which we invented. (English)
reference URL
https://patents.google.com/patent/EP2754077A4
title
O. Alter, "Genomic Tensor Analysis for Medical Assessment and Prediction," European Nationalized Patent Cooperation Treaty (PCT) EP 2754077 A4 (Filed September 2012). (English)
reference URL
https://patents.google.com/patent/US20140249762A1
title
O. Alter, "Genomic Tensor Analysis for Medical Assessment and Prediction," United States Nationalized PCT US 20140249762 A1 (Filed March 2014). (English)
reference URL
https://patents.google.com/patent/US20180122507A1
title
O. Alter, "Genetic Alterations in Ovarian Cancer," United States Nationalized PCT US 20180122507 A1 (Filed April 2014). (English)
reference URL
https://patents.google.com/patent/US20180301223A1
title
O. Alter, "Advanced Tensor Decompositions for Computational Assessment and Prediction from Data," United States Nationalized PCT US 20180301223 A1 (Filed April 2014). (English)
reference URL
https://patents.google.com/patent/US10202643B2
title
O. Alter, "Genetic Alterations in Glioma," United States Patent US 10202643 B2 (Issued February 2019). (English)
reference URL
https://patents.google.com/patent/EP2773777A4
title
O. Alter, "Genetic Alterations in Glioblastoma," European Patent EP 2773777 A4 (Issued May 2020). (English)
geneticist
0 references
mathematician
0 references
physicist
0 references
notable work
Quantum Measurement of a Single System
publisher
Wiley
publication date
25 May 2001
together with
Yoshihisa Yamamoto
David B. Oberman
subject has role
corresponding author
nominated for
Outstanding Doctoral Thesis Research in Atomic, Molecular, or Optical Physics (DAMOP) Award
3 references
reference URL
https://alterlab.org/publications/Alter_Yamamoto_Wiley_2001.pdf
title
Alter Lab (English)
DOI
10.1002/9783527617128
publisher
Wiley
quotation
While they collaborated on the research presented in this book ... Alter was a doctoral student at the Department of Applied Physics at Stanford. She was selected as a finalist for the American Physical Society Award for Outstanding Doctoral Thesis Research in Atomic, Molecular or Optical Physics for 1998 for this work. (English)
reference URL
https://alterlab.org/presentations/Alter_Ph.D._Dissertation_1999_Slides.pdf
title
Alter Lab (English)
award received
nominated for
Outstanding Doctoral Thesis Research in Atomic, Molecular, or Optical Physics (DAMOP) Award
point in time
1998
for work
Quantum Measurement of a Single System
nominated by
American Physical Society
1 reference
reference URL
https://aps.org/publications/apsnews/199808/damop.cfm
publisher
American Physical Society
publication date
August 1998
quotation
The DAMOP Thesis Award recognizes doctoral thesis research of outstanding quality and achievement in atomic, molecular or optical physics, and encourages effective written and oral presentation of research results. The other four finalists, and their thesis topics, were Orly Alter (Stanford University), "Impossibility of Determining the Quantum Wavefunction of a Single System and Fundamental Limit to External Force Detection"... (English)
discoverer or inventor
eigengene
image
Eigengenes following Alter et al. PNAS 2000 and Alter and Golub PNAS 2006.png
7,642 × 6,061; 3.58 MB
media legend
Eigengenes computed by the SVD of a genes x samples matrix that tabulates, e.g., the mRNA expression of the genes across the samples. (English)
depicts
Singular value decomposition for genome-wide expression data processing and modeling
Singular Value Decomposition for Gene Expression Data Processing and Modeling
Singular value decomposition of genome-scale mRNA lengths distribution reveals asymmetry in RNA gel electrophoresis band broadening
SVD identifies transcript length distribution functions from DNA microarray data and reveals evolutionary forces globally affecting GBM metabolism
time of discovery or invention
1990s
2 references
Wikimedia import URL
https://en.wiktionary.org/wiki/Citations:eigengene
https://en.wiktionary.org/wiki/User_talk:Orly.alter
retrieved
29 July 2022
reference URL
https://physics.cancer.gov/research-funding/utah#investigators
publisher
Physical Sciences in Oncology Network
part of
National Cancer Institute
publication date
September 2015
subject named as
Dr. Orly Alter
quotation
Dr. Orly Alter is a USTAR associate professor of bioengineering and human genetics at the Scientific Computing and Imaging Institute and the Huntsman Cancer Institute at the University of Utah. Inventor of the "eigengene," she pioneered the matrix and tensor modeling of large-scale molecular biological data, which, as she demonstrated, can be used to correctly predict previously unknown cellular mechanisms. (English)
multi-tensor decomposition
image
Tensor Generalized Singular Value Decomposition following et int. Alter PLoS One 2015 and Alter NCI Physical Sciences in Oncology 2015.jpg
5,000 × 6,495; 3.05 MB
media legend
The tensor generalized singular value decomposition is one of the multi-tensor decompositions, invented to simultaneously identify the similar and dissimilar among, and create a single coherent model from any data types, of any number and dimensions. (English)
time of discovery or invention
2000s
1 reference
reference URL
https://physics.cancer.gov/research-funding/utah
publisher
Physical Sciences in Oncology Network
part of
National Cancer Institute
funder
United States Department of Energy
together with
Alfred P. Sloan Foundation
start time
1999
end time
2003
title
DOE/Sloan Foundation Postdoctoral Fellowship in Computational Molecular Biology: Analytical and Computational Tools for Genome-Wide Gene Expression Data Analysis (English)
subject has role
principal investigator
1 reference
stated in
Dimensions
reference URL
https://app.dimensions.ai/details/grant/grant.8700796
National Human Genome Research Institute
part of
National Institutes of Health
title
NIH/National Human Genome Research Institute (NHGRI) K01 Individual Mentored Research Scientist Development Award in Genomic Research and Analysis: Mathematical Tools for Genome-Wide Gene Expression Data Analysis (English)
start time
2000
end time
2005
subject has role
principal investigator
1 reference
stated in
Dimensions
reference URL
https://app.dimensions.ai/details/grant/grant.2404577
National Human Genome Research Institute
part of
National Institutes of Health
title
NIH/National Human Genome Research Institute (NHGRI) R01 Project: Tensor Computations for Modeling Large-Scale Molecular Biological Data – from Discovery of Patterns to Discovery of Principles of Nature (English)
start time
2007
end time
2015
subject has role
principal investigator
1 reference
stated in
Dimensions
reference URL
https://app.dimensions.ai/details/grant/grant.2529292
National Science Foundation Division of Mathematical Sciences
part of
National Science Foundation
title
NSF/Division of Mathematical Sciences (DMS) Faculty Early Career Development (CAREER) Award: Integrative and Comparative Tensor Algebra Models of DNA Microarray Data from Different Studies of the Cell Cycle (English)
start time
2009
end time
2015
subject has role
principal investigator
1 reference
stated in
Dimensions
reference URL
https://app.dimensions.ai/details/grant/grant.3096148
Commons gallery
Orly Alter
0 references
Commons category
Orly Alter
0 references

Identifiers

VIAF ID
2696129
0 references
Academic Tree ID
349239
0 references
Freebase ID
/m/0bqvfll
0 references
MR Author ID
657888
0 references
Prabook ID
444090
0 references
YouTube video ID
opiYfUKDJ2U
subject named as
Multi-Tensor Decompositions for Personalized Cancer Diagnostics, Prognostics, and Therapeutics
number of viewers/listeners
2,223
publication date
1 February 2020
duration
3,625.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
20 July 2022
1 reference
stated in
YouTube
s4ezu0OHKAs
subject named as
Multi-Tensor Decompositions for Personalized Cancer Diagnostics, Prognostics, and Therapeutics
number of viewers/listeners
2,058
publication date
31 January 2020
language of work or name
English
duration
3,665.0 second
YouTube channel ID
UCd6MoB9NC6uYN2grvUNT-Zg
point in time
20 July 2022
1 reference
stated in
YouTube
rXEbMnL8iGc
subject named as
Discovering Genome-Scale Predictors of Survival and Response to Treatment with Multi-Tensor Decompositions
number of viewers/listeners
1,213
publication date
25 October 2020
duration
1,250.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
20 July 2022
1 reference
stated in
YouTube
5LKYwVby9Rc
subject named as
Retrospective Clinical Trial Experimentally Validates Glioblastoma Genome-Wide Pattern of DNA Copy-Number Alterations Predictor of Survival
number of viewers/listeners
929
publication date
9 February 2021
duration
1,223.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
20 July 2022
1 reference
stated in
YouTube
oMfYXLZfrmo
subject named as
How High-Dimensional Multi-Tensor Machine Learning Is Being Used to Improve the Prognosis, Diagnosis, and Treatment of Gliomas
number of viewers/listeners
367
publication date
14 December 2021
duration
1,262.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
20 July 2022
1 reference
stated in
YouTube
oENp857ATYo
subject named as
Using Machine Learning to Study How Brains Represent Language Meaning: Tom M. Mitchell
number of viewers/listeners
792
publication date
17 February 2018
duration
3,571.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
31 August 2022
together with
Tom M. Mitchell
0 references
6QZDLUwBXro
subject named as
Evolution of MATLAB: Cleve B. Moler
number of viewers/listeners
542
publication date
29 September 2017
duration
3,773.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
31 August 2022
together with
Cleve Moler
0 references
5JI6dD-5GkI
subject named as
The ENCODE Project and Us: Peter J. Bickel
number of viewers/listeners
459
publication date
7 April 2015
duration
3,359.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
31 August 2022
together with
Peter J. Bickel
0 references
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subject named as
Why Computer Scientists Need to Understand Consumer Behavior: Prabhakar Raghavan
number of viewers/listeners
450
publication date
30 April 2014
duration
3,727.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
31 August 2022
together with
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0 references
Z36AwoLh_ic
subject named as
Bistability and Trigger Waves in Mitosis: James E. Ferrell, Jr.
number of viewers/listeners
925
publication date
19 April 2013
duration
4,160.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
31 August 2022
together with
James Ferrell
0 references
GU7m4oNalsM
subject named as
COMBREX – Genomes, Computers and Experimentation in Biology: Sir Richard J. Roberts
number of viewers/listeners
287
publication date
16 April 2013
duration
3,411.0 second
YouTube channel ID
UC3pGZnzlrGPCYFedjig-fQw
point in time
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together with
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0 references
 
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