pravastatin (Q1240093)

pravastatin (English)

(3R,5R)-7-[(1S,2S,6S,8S,8aS)-6-hydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid

4 October 2016

stereoisomer of

2 references

based on heuristic

inferred from InChIKey

1 reference

(3S,5S)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid

1 reference

based on heuristic

inferred from InChI

chemical formula

C₂₃H₃₆O₇

1 reference

pravastatin (English)

19 November 2016

canonical SMILES

CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O

1 reference

pravastatin (English)

19 November 2016

isomeric SMILES

CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O

1 reference

pravastatin (English)

https://www.whocc.no/atc_ddd_index/?code=C10AA03

19 November 2016

defined daily dose

30 milligram

route of administration

oral administration

1 reference

reference URL

1 reference

14 February 2018

World Health Organisation international non-proprietary name

pravastatin (English)

1 reference

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium

pravastatin (English)

4 October 2016

1 reference

Aspergillus sclerotiorum

1 reference

Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178.

medical condition treated

1 reference

13 December 2016

coronary artery disease

1 reference

13 December 2016

familial hyperlipidemia

1 reference

13 December 2016

1 reference

Drug Indications Extracted from FAERS

13 December 2016

1 reference

2 October 2018

acute myeloid leukemia

1 reference

Drug Indications Extracted from FAERS

2 October 2018

rare dyslipidemia

1 reference

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

established

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2R)-daptomycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(S)-(−)-colchicine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(S)-(−)-colchicine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2R)-daptomycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

clarithromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

established

A reference set of clinically relevant adverse drug-drug interactions

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

erythromycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category X

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Pravastatin

5 August 2017

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

D017035

15 March 2018

anticholesteremic agents

1 reference

InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1

Medical Subject Headings

15 March 2018

Pravastatin

0 references

Identifiers

InChI

1 reference

pravastatin (English)

TUZYXOIXSAXUGO-PZAWKZKUSA-N

19 November 2016

InChIKey

2 references

pravastatin (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

81093-37-0

2 references

Global Substance Registration System

UNII

KXO2KT9N0G

pravastatin (English)

TUZYXOIXSAXUGO-PZAWKZKUSA-N

19 November 2016

InChIKey

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=81093-37-0

1 reference

Pravastatin (English)

19 November 2016

1 reference

pravastatin (English)

19 November 2016

Reaxys registry number

4825538

1 reference

pravastatin (English)

4 October 2016

ChEBI ID

63618

mapping relation type

1 reference

PRAVASTATIN (English)

19 November 2016

1 reference

splash10-00di-0002900000-bd7fd66d793ae64426ff

PRAVASTATIN (English)

19 November 2016

1 reference

MassBank accession ID

0 references

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splash10-0udi-4809000000-0ed5a8797dfc49ecf5af

0 references

splash10-0udi-2900000000-91b125182ce5d90f16ab

0 references

splash10-0udi-1900000000-e8fc6384260de93c5aa8

0 references

splash10-0udi-1900000000-11e99968bc0ba393b6f9

0 references

splash10-0udi-4900000000-0e4265e6dc1468c1471d

0 references

splash10-00di-0002900000-8795ee00dded0ef8be48

0 references

splash10-0udi-3709000000-aa45be15af0471c0a46e

0 references

splash10-0udi-2900000000-5617409991f5c58e5130

0 references

splash10-0udi-2900000000-2bf5c13979a639625d1c

0 references

splash10-0udi-2900000000-9a233e521607e82ab7a0

0 references

splash10-0udi-0900000000-2083dfbb67bf2b03ccf9

0 references

splash10-0uk9-0009000000-4b2c09a295ba7f3ce41b

0 references

splash10-00di-0607900000-e57e263ad3f74bfda195

0 references

HSDB ID

8368

1 reference

Hazardous Substances Data Bank

28 October 2019

Pravastatin (English)

10 May 2021

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

689-360-3

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.216.225

27 December 2018

ECHA Substance Infocard ID

+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]-heptanoic acid (English)

quotation

CAS no.: 81093-37-0 (English)

100.216.225

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.216.225

27 December 2018

+)-(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1,2,6,7,8,8a-hexahydro-1-naphthyl]-heptanoic acid (English)

quotation

CAS no.: 81093-37-0 (English)

1 reference