streptomycin (Q192717)

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chemical compound
  • SM
  • STREPTOMYCIN
  • [2-Deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{n',n'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
  • Kantrex
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • streomycin
  • 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • Streptomycin
  • Estreptomicina
  • Streptomyzin
  • Streptomicina
edit
Language Label Description Also known as
English
streptomycin
chemical compound
  • SM
  • STREPTOMYCIN
  • [2-Deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{n',n'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
  • Kantrex
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • streomycin
  • 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • Streptomycin
  • Estreptomicina
  • Streptomyzin
  • Streptomicina

Statements

mass
581.266 dalton
1 reference
stated in
PubChem
PubChem CID
19649
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
chemical formula
C₂₁H₃₉N₇O₁₂
1 reference
stated in
PubChem
PubChem CID
19649
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
canonical SMILES
CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O
1 reference
stated in
PubChem
PubChem CID
19649
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
isomeric SMILES
CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]3NC(N)=N)O[C@@H](C)[C@]2(O)C=O
1 reference
stated in
Global Substance Registration System
UNII
Y45QSO73OB
retrieved
14 February 2018
found in taxon
Streptomyces griseus
47 references
stated in
Effect of sclerin on production of the aminoglycoside antibiotics accompanied by salvage function in Streptomyces.
stated in
BIOSYNTHESIS OF STREPTOMYCINS
stated in
Streptomycin biosynthesis inStreptomyces griseusII. Adjacent genomic location of biosynthetic genes and one of two streptomycin resistance genes
stated in
Streptomycin biosynthesis inStreptomyces griseusI. Characterization of streptomycin-idiotrophic mutants
stated in
Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus
stated in
Streptomyces antibiotics; structure of streptomycin
stated in
Strain- and species-specific distribution of the streptomycin gene cluster and kan-related sequences in Streptomyces griseus.
stated in
tmRNA of Streptomyces collinus and Streptomyces griseus during the growth and in the presence of antibiotics
stated in
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: nucleotide sequence of three genes and analysis of transcriptional activity
stated in
Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus.
stated in
Detection and properties of A-factor-binding protein from Streptomyces griseus
stated in
Identification and gene disruption of small noncoding RNAs in Streptomyces griseus.
stated in
The A-factor regulatory cascade and cAMP in the regulation of physiological and morphological development in Streptomyces griseus
stated in
A-factor as a microbial hormone that controls cellular differentiation and secondary metabolism in Streptomyces griseus
stated in
The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A-factor receptor.
stated in
Nucleotide sequence of the streptomycinphosphotransferase and amidinotransferase genes from Streptomyces griseus
stated in
Biosynthesis of streptomycin enzymic oxidation of dihydrostreptomycin (6-phosphate) to streptomycin (6-phosphate) with a particulate fraction of Streptomyces griseus
stated in
STREPTOMYCIN FORMATION BY INTACT MYCELIUM OF STREPTOMYCES GRISEUS
stated in
Activation of secondary metabolite-biosynthetic gene clusters by generating rsmG mutations in Streptomyces griseus
stated in
Cloning and characterization of a gene involved in aerial mycelium formation in Streptomyces griseus.
stated in
Identification of an A-factor-dependent promoter in the streptomycin biosynthetic gene cluster of Streptomyces griseus.
stated in
Possible involvement of cAMP in aerial mycelium formation and secondary metabolism in Streptomyces griseus.
stated in
Ribosomal ribonucleic acids from Streptomyces griseus.
stated in
Dependence on reporter gene of apparent activity in gene fusions of a Streptomyces griseus streptomycin biosynthesis promoter
stated in
Isolation and characterization of pock-forming plasmids for Streptomyces griseus from soil actinomycetes
stated in
Mutants blocked in streptomycin production in Streptomyces griseus - the role of A-factor
stated in
Gene cluster for streptomycin biosynthesis in Streptomyces griseus: analysis of a central region including the major resistance gene.
stated in
Genetics of streptomycin production in Streptomyces griseus: molecular structure and putative function of genes strELMB2N
stated in
Physiological factors affecting streptomycin production byStreptomyces griseusATCC 12475 in batch and continuous culture
stated in
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350
stated in
An A-factor-dependent extracytoplasmic function sigma factor (sigma(AdsA)) that is essential for morphological development in Streptomyces griseus
stated in
Sporulation of Streptomyces griseus in submerged culture.
stated in
Intracellular cyclic adenosine 3′,5′-monophosphate levels and streptomycin production in cultures of Streptomyces griseus
stated in
Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor
stated in
Genetic analysis of A-factor synthesis in Streptomyces coelicolor A3(2) and Streptomyces griseus
stated in
Properties of C-terminal truncated derivatives of the activator, StrR, of the streptomycin biosynthesis in Streptomyces griseus
stated in
An alternative sigma factor governs the principal sigma factor in Streptomyces griseus.
stated in
Strict regulation of morphological differentiation and secondary metabolism by a positive feedback loop between two global regulators AdpA and BldA in Streptomyces griseus
stated in
Crystal structure of L-arginine:inosamine-phosphate amidinotransferase StrB1 from Streptomyces griseus: an enzyme involved in streptomycin biosynthesis
stated in
Cloning and characterization of the A-factor receptor gene from Streptomyces griseus
stated in
Biosynthesis of streptomycin. Purification and properties of a dTDP-L-dihydrostreptose: streptidine-6-phosphate dihydrostreptosyltransferase from Streptomyces griseus
stated in
Myo-inositol-1-phosphate synthase from streptomyces griseus (Studies on the biosynthesis of cyclitols, XXXVIII1)
stated in
The A-factor-binding protein of Streptomyces griseus negatively controls streptomycin production and sporulation
stated in
Nucleotide sequence of a principal sigma factor gene (hrdB) of Streptomyces griseus
stated in
Intracellular levels of guanosine 5′-diphosphate 3′-diphosphate (ppGpp) and guanosine 5′-triphosphate 3′-diphosphate (pppGpp) in cultures of Streptomyces griseus producing streptomycin
stated in
Cross-interaction of anti-σH factor RshA with BldG, an anti-sigma factor antagonist in Streptomyces griseus.
stated in
Resistance to streptomycin in a producing strain of Streptomyces griseus
significant drug interaction
Commons category
Streptomycin
0 references

Identifiers

NDL Authority ID
00571777
0 references
PubChem CID
19649
1 reference
stated in
PubChem
PubChem CID
19649
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
Reaxys registry number
74498
1 reference
stated in
ChEBI
ChEBI ID
17076
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
HSDB ID
1768
1 reference
stated in
Hazardous Substances Data Bank
HSDB ID
1768
publication date
28 October 2019
title
Streptomycin (English)
retrieved
10 May 2021
ATC code
J01GA01
1 reference
stated in
DrugBank
DrugBank ID
01082
language of work or name
English
title
Streptomycin (English)
publication date
17 November 2015
A07AA04
1 reference
stated in
DrugBank
DrugBank ID
01082
language of work or name
English
title
Streptomycin (English)
publication date
17 November 2015
J01GA
0 references
UNII
Y45QSO73OB
0 references
KEGG ID
D08531
1 reference
stated in
ChEBI
ChEBI ID
17076
language of work or name
English
title
streptomycin (English)
retrieved
19 October 2016
C00413
0 references
PDB ligand ID
SRY
0 references
NALT ID
7873
0 references
PDB structure ID
WordNet 3.1 Synset ID
04343518-n
1 reference
stated in
GF WordNet
 
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