The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology (Q35401594)

8 August 2017

6 references

13 March 2019

12 September 2019

2 October 2019

6 October 2019

11 October 2019

12 October 2019

The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology (English)

1 reference

human musculoskeletal system

8 August 2017

6 references

13 March 2019

12 September 2019

2 October 2019

6 October 2019

11 October 2019

12 October 2019

1 reference

12 September 2019

1 reference

2 October 2019

1 reference

6 October 2019

1 reference

11 October 2019

1 reference

12 October 2019

1 reference

0 references

Susanne G Grässel

1

1 reference

PubMed ID

25789373

8 August 2017

language of work or name

1 reference

1 January 2014

1 reference

Arthritis Research and Therapy

8 August 2017

7 references

8 August 2017

13 March 2019

12 September 2019

2 October 2019

6 October 2019

11 October 2019

12 October 2019

16

1 reference

8 August 2017

485

1 reference

8 August 2017

6

1 reference

Creative Commons Attribution

8 August 2017

6 references

13 March 2019

12 September 2019

2 October 2019

6 October 2019

11 October 2019

12 October 2019

0 references

on focus list of Wikimedia project

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s13075-014-0485-1

0 references

cites work

Effects of neuropeptides and mechanical loading on bone cell resorption in vitro

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Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis

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Role of peripheral nerve fibres in acute and chronic inflammation in arthritis

27 July 2018

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Mechanisms of chronic pain in osteoarthritis

27 July 2018

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The neuropeptide VIP regulates the expression of osteoclastogenic factors in osteoblasts

27 July 2018

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β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B.

27 July 2018

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27 July 2018

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Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc.

27 July 2018

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Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members.

27 July 2018

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Role of neurotrophin signalling in the differentiation of neurons from dorsal root ganglia and sympathetic ganglia

27 July 2018

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Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro

27 July 2018

1 reference

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Osteotropic effects by the neuropeptides calcitonin gene-related peptide, substance P and vasoactive intestinal peptide.

27 July 2018

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27 July 2018

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Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes

27 July 2018

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27 July 2018

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Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis

27 July 2018

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Deletions of genes encoding calcitonin/alpha-CGRP, amylin and calcitonin receptor have given new and unexpected insights into the function of calcitonin receptors and calcitonin receptor-like receptors in bone

27 July 2018

1 reference

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Expression of Semaphorin-3A and its receptors in endochondral ossification: potential role in skeletal development and innervation.

27 July 2018

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Neuronal signaling and the regulation of bone remodeling

27 July 2018

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The neuropeptide VIP potentiates IL-6 production induced by proinflammatory osteotropic cytokines in calvarial osteoblasts and the osteoblastic cell line MC3T3-E1.

27 July 2018

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Neuropeptidergic regulation of bone resorption and bone formation

27 July 2018

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

27 July 2018

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Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide

27 July 2018

1 reference

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Bone and brain: a review of neural, hormonal, and musculoskeletal connections.

27 July 2018

1 reference

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UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte.

27 July 2018

1 reference

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Cyclic adenosine monophosphate/protein kinase A mediates parathyroid hormone/parathyroid hormone-related protein receptor regulation of osteoclastogenesis and expression of RANKL and osteoprotegerin mRNAs by marrow stromal cells

27 July 2018

1 reference

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Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur

27 July 2018

1 reference

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Neuropeptides in experimental and degenerative arthritis.

27 July 2018

1 reference

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Distribution of beta-endorphin and substance P in the shoulder joint of the dog before and after a low impact exercise programme

27 July 2018

1 reference

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International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors

27 July 2018

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Falls, fractures, and osteoporosis after stroke: time to think about protection?

27 July 2018

1 reference

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Composition and structure of articular cartilage: a template for tissue repair

27 July 2018

1 reference

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Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development

27 July 2018

1 reference

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Neurohormones and catecholamines as functional components of the bone marrow microenvironment.

27 July 2018

1 reference

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Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis

27 July 2018

1 reference

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The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages.

27 July 2018

1 reference

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Is bone a target-tissue for the nervous system? New advances on the understanding of their interactions

27 July 2018

1 reference

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Supralesional and sublesional bone mineral density in spinal cord-injured patients

27 July 2018

1 reference

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Fracture healing and callus innervation after peripheral nerve resection in rats.

27 July 2018

1 reference

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Mechanisms of oxyradical production in substance P stimulated rheumatoid synovial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Immunohistochemical and ultrastructural localization of CGRP-positive nerve fibers at the epiphyseal trabecules facing the growth plate of rat femurs.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

The mammalian tachykinin receptors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

??- and ??-Adrenergic Receptor Subtypes Properties, Distribution and Regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Distribution of nerve endings and sensory neuropeptides in rat synovium, meniscus and bone.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Calcitonin gene-related peptide, substance P and GAP-43/B-50 immunoreactivity in the normal and arthrotic knee joint of the mouse

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Substance P activates the Wnt signal transduction pathway and enhances the differentiation of mouse preosteoblastic MC3T3-E1 cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

The innervation of synovium of human osteoarthritic joints in comparison with normal rat and sheep synovium.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Neuropeptide SP activates the WNT signal transduction pathway and enhances the proliferation of bone marrow stromal stem cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Substance P and norepinephrine modulate murine chondrocyte proliferation and apoptosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Semaphorin 3A is expressed in human osteoarthritic cartilage and antagonizes vascular endothelial growth factor 165-promoted chondrocyte migration: an implication for chondrocyte cloning.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Vasoactive intestinal peptide induces vascular endothelial growth factor production in human HaCaT keratinocytes via MAPK pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Calcitonin gene-related peptide (CGRP) inhibits apoptosis in human osteoblasts by β-catenin stabilization.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Beta-adrenergic signals regulate adipogenesis of mouse mesenchymal stem cells via cAMP/PKA pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Beta2-adrenoreceptor ligands regulate osteoclast differentiation in vitro by direct and indirect mechanisms

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Lower density of synovial nerve fibres positive for calcitonin gene-related peptide relative to substance P in rheumatoid arthritis but not in osteoarthritis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Beta2-adrenergic receptors expressed on murine chondrocytes stimulate cellular growth and inhibit the expression of Indian hedgehog and collagen type X.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Preponderance of sensory versus sympathetic nerve fibers and increased cellularity in the infrapatellar fat pad in anterior knee pain patients after primary arthroplasty.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

A substance P receptor (NK1) antagonist enhances the widespread osteoporotic effects of sciatic nerve section.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Neuropeptide effects on rat chondrocytes and perichondrial cells in vitro

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Development of the innervation of long bones: expression of the growth-associated protein 43.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Retrograde tracing and neuropeptide immunohistochemistry of sensory neurones projecting to the cartilaginous distal femoral epiphysis of young rats.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Developmental changes in the transmitter properties of sympathetic neurons that innervate the periosteum.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Effects of cyclic adenosine 3',5'-monophosphate on chondrocyte terminal differentiation and cartilage-matrix calcification

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Substance P immunohistochemical study of the sensory innervation of normal subchondral bone in the equine metacarpophalangeal joint.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

A mechanism for sympathectomy-induced bone resorption in the middle ear.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Activation of macrophages by substance P: induction of oxidative burst and thromboxane release.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Mechanotransduction via integrins and interleukinâ 4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13075-014-0485-1

Norepinephrine Inhibition of Mesenchymal Stem Cell and Chondrogenic Progenitor Cell Chondrogenesis and Acceleration of Chondrogenic Hypertrophy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13075-014-0485-1

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4395972

Effect of nerve injury on fracture healing: Callus formation studied in the rat

15 November 2018

1 reference

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https://api.crossref.org/works/10.1186%2FS13075-014-0485-1

Tachykinin expression in cartilage and function in human articular chondrocyte mechanotransduction

21 January 2018

1 reference

12 December 2020

The inhibitory effects of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide on osteoclast formation are associated with upregulation of osteoprotegerin and downregulation of RANKL and RANK

1 reference

12 December 2020

Substance P- and CGRP-immunoreactive nerves in bone

1 reference

12 December 2020

The neuronal regulation of fracture healing. Effects of sciatic nerve resection in rat tibia

1 reference

12 December 2020

Mechanical stimulation induces preprotachykinin gene expression in osteoarthritic chondrocytes which is correlated with modulation of the transcription factor neuron restrictive silence factor

1 reference

12 December 2020

Peptide containing nerves in human synovium: immunohistochemical evidence for decreased innervation in rheumatoid arthritis

1 reference

12 December 2020

The effect of combined regulation of the expression of peroxisome proliferator-activated receptor-γ and calcitonin gene-related peptide on alcohol-induced adipogenic differentiation of bone marrow mesenchymal stem cells

1 reference

12 December 2020

Callus formation and the rate of healing of femoral fractures in patients with head injuries

1 reference

12 December 2020

Innervation of the human knee joint by substance-P fibers

1 reference

12 December 2020

Site-specific CGRP innervation coincides with bone formation during fracture healing and modeling: A study in rat angulated tibia

1 reference

12 December 2020

Immunohistochemical localization of calcitonin gene-related peptide and substance P in the rat knee cartilage at birth

1 reference

12 December 2020

Production of neuropeptide substance P by synovial fibroblasts from patients with rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Calcitonin gene-related peptide, substance P, and tyrosine hydroxylase-immunoreactive innervation of rat bone marrows: an immunohistochemical and ultrastructural investigation on possible efferent and afferent mechanisms

1 reference

12 December 2020

Expression of synovial fluid and articular cartilage VIP in human osteoarthritic knee: a new indicator of disease severity?

1 reference

12 December 2020

Changes of substance P during fracture healing in ovariectomized mice

1 reference

12 December 2020

Innervation pattern of different cartilaginous tissues in the rat

1 reference

12 December 2020

1 reference

12 December 2020

Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease

1 reference

12 December 2020

Effect of neuropeptides on production of inflammatory cytokines by human monocytes

1 reference

12 December 2020

Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis

1 reference

12 December 2020

Evidence for a neuropathic contribution to the development of spontaneous knee osteoarthrosis in a mouse model

1 reference

12 December 2020

Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling

1 reference

12 December 2020

Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations

1 reference

12 December 2020

Detection of pain-related molecules in the subchondral bone of osteoarthritic knees

1 reference

12 December 2020

Effect of the neuropeptide substance P on the rat bone marrow-derived osteogenic cells in vitro

1 reference

12 December 2020

10.1186/S13075-014-0485-1

Identifiers

DOI

1 reference

PubMed ID

25789373

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference

PubMed ID

25789373