Cellular senescence in osteoarthritis pathology. (Q37678205)

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10 July 2020

Cellular senescence in osteoarthritis pathology (English)

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3

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author name string

Kendal McCulloch

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1

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Gary J Litherland

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2

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publication date

26 January 2017

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4 references

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17 June 2019

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16

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page(s)

210-218

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issue

2

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Creative Commons Attribution

9 April 2020

copyright license

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on focus list of Wikimedia project

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

23 August 2017

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23 August 2017

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23 August 2017

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SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

23 August 2017

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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

23 August 2017

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

23 August 2017

1 reference

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Replicative senescence, aging and growth-regulatory transcription factors

23 August 2017

1 reference

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Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

23 August 2017

1 reference

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

23 August 2017

1 reference

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Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

23 August 2017

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

23 August 2017

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23 August 2017

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Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts

23 August 2017

1 reference

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Senescent cells harbour features of the cancer epigenome.

23 August 2017

1 reference

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Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation.

6 September 2017

1 reference

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cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.

6 September 2017

1 reference

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Cbfa1 is a positive regulatory factor in chondrocyte maturation

6 September 2017

1 reference

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Spatial coupling of mTOR and autophagy augments secretory phenotypes.

6 September 2017

1 reference

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Synovial tissue hypoxia and inflammation in vivo

14 September 2017

1 reference

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Growth stimulation leads to cellular senescence when the cell cycle is blocked

14 September 2017

1 reference

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Recovery of function in osteoarthritic chondrocytes induced by p16INK4a-specific siRNA in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Correlation between senescence-associated beta-galactosidase expression in articular cartilage and disease severity of patients with knee osteoarthritis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Targeting bromodomain-containing protein 4 (BRD4) benefits rheumatoid arthritis

28 September 2017

1 reference

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DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Autophagy maintains stemness by preventing senescence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice

25 June 2018

1 reference

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Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Vascular endothelial growth factor in articular cartilage of healthy and osteoarthritic human knee joints.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Regulation of two E2F-related genes in presenescent and senescent human fibroblasts

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Aberrant deoxyribonucleic acid methylation in human thyroid tumors

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration.

1 September 2018

1 reference

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Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes

1 September 2018

1 reference

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Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Cyclin D1 overexpression permits the reproducible detection of senescent human vascular smooth muscle cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Synovial tissue inflammation in early and late osteoarthritis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Apoptosis of terminal hypertrophic chondrocytes in an in vitro model of endochondral ossification

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Development and regulation of osteophyte formation during experimental osteoarthritis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

Telomere erosion and senescence in human articular cartilage chondrocytes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334539

1 September 2018

Senescence comes of age

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FACEL.12562

A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FACEL.12562

Osteoarthritic lesions: involvement of three different collagenases

21 January 2018

1 reference

12 December 2020

MMP-13 is induced during chondrocyte hypertrophy

1 reference

12 December 2020

Joint injury in young adults and risk for subsequent knee and hip osteoarthritis

1 reference

12 December 2020

Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis

1 reference

12 December 2020

Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy

1 reference

12 December 2020

The relationship between ultra-short telomeres, aging of articular cartilage and the development of human hip osteoarthritis

1 reference

12 December 2020

The role of chondrocyte senescence in osteoarthritis

1 reference

12 December 2020

Identifiers

DOI

10.1111/ACEL.12562

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28124466%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28124466%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference