Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/ RNS generation. (Q41714460)

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Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/ RNS generation (English)

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reactive nitrogen species

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Journal of Biomedical Science

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

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The missing link: a single unifying mechanism for diabetic complications.

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

6 June 2018

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Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo

6 June 2018

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6 June 2018

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

6 June 2018

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Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s

6 June 2018

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High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

6 June 2018

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6 June 2018

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Evidence of neuronal oxidative damage in Alzheimer's disease.

6 June 2018

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Associations between criteria air pollutants and asthma

6 June 2018

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Hyperglycemic pseudohypoxia and diabetic complications.

6 June 2018

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Free radicals in disease processes: a compilation of cause and consequence

6 June 2018

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Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Review of the genotoxicity of nitrogen oxides

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

The association of clinical and neurological findings and its bearing on the classification and aetiology of Alzheimer's disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Three models of free radical-induced cell injury

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Role of free radicals and catalytic metal ions in human disease: an overview

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

The role of alterations in membrane lipid composition in enabling physiological adaptation of organisms to their physical environment

6 June 2018

1 reference

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Role of oxidative stress in development of complications in diabetes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Biologically relevant metal ion-dependent hydroxyl radical generation. An update

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Metformin Attenuates Aβ Pathology Mediated Through Levamisole Sensitive Nicotinic Acetylcholine Receptors in a C. elegans Model of Alzheimer's Disease.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Targeting mitochondria as therapeutic strategy for metabolic disorders.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Matrix metalloproteinases: all the RAGE in the acute respiratory distress syndrome

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

The voltage-dependent anion channel-1 modulates apoptotic cell death.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Vascular dysfunction of venous bypass conduits is mediated by reactive oxygen species in diabetes: role of endothelin-1.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Radiation-induced peroxidation and fragmentation of lipids in a model membrane

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Protein oxidation in the brain in Alzheimer's disease

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Skin low molecular weight antioxidants and their role in aging and in oxidative stress.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Lipid peroxidation in rat lung induced by neuroleptanalgesia and its components.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Regional membrane phospholipid alterations in Alzheimer's disease.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Natural history of colonization with vancomycin-resistant Enterococcus faecium

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Cerebral function in diabetes mellitus.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5606025

Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved

18 August 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12929-017-0379-Z

Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12929-017-0379-Z

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12929-017-0379-Z

Free Radicals in Biological Materials

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12929-017-0379-Z

Hydrogen peroxide production during experimental protein glycation

21 January 2018

1 reference

12 December 2020

Reactive oxygen species: the unavoidable environmental insult?

1 reference

12 December 2020

Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors

1 reference

12 December 2020

High glucose inhibits glucose-6-phosphate dehydrogenase via cAMP in aortic endothelial cells

1 reference

12 December 2020

Reduced plasma peroxyl radical trapping capacity and increased susceptibility of LDL to oxidation in poorly controlled IDDM

1 reference

12 December 2020

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

12 December 2020

Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis

1 reference

12 December 2020

Free radical-mediated lung response to the monofunctional sulfur mustard butyl 2-chloroethyl sulfide after subcutaneous injection

1 reference

12 December 2020

Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

1 reference

12 December 2020

10.1186/S12929-017-0379-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28927401%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28927401%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference