fluvastatin (Q417942)

fluvastatin (English)

19 October 2016

2 references

inferred from InChIKey

(3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-yl-2-indolyl]-3,5-dihydroxy-6-heptenoic acid

1 reference

fluvastatin sodium anti-isomer free acid

1 reference

(3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

1 reference

(3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-yl-2-indolyl]-3,5-dihydroxy-6-heptenoic acid

1 reference

chemical formula

C₂₄H₂₆FNO₄

1 reference

fluvastatin (English)

19 October 2016

canonical SMILES

CC(C)N1C2=CC=CC=C2C(=C1C=CC(CC(CC(=O)O)O)O)C3=CC=C(C=C3)F

1 reference

fluvastatin (English)

19 October 2016

isomeric SMILES

CC(C)N1C2=CC=CC=C2C(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C3=CC=C(C=C3)F

1 reference

fluvastatin (English)

19 October 2016

defined daily dose

60 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=C10AA04

World Health Organisation international non-proprietary name

fluvastatin (English)

1 reference

published in

Recommended INN: List 30

publication date

1990

medical condition treated

1 reference

13 December 2016

coronary artery disease

1 reference

13 December 2016

familial hyperlipidemia

1 reference

13 December 2016

1 reference

Drug Indications Extracted from FAERS

13 December 2016

1 reference

lipid metabolism disorder

2 October 2018

start time

31 December 1993

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/4L066368AS

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021192s019lbl.pdf

atherosclerosis

start time

31 December 1993

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/4L066368AS

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021192s019lbl.pdf

hypercholesterolemia

start time

31 December 1993

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/4L066368AS

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021192s019lbl.pdf

significant drug interaction

(S)-(−)-colchicine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2R)-daptomycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(S)-(−)-colchicine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rac-warfarin

Retroperitoneal hemorrhage

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2R)-daptomycin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

3-hydroxy-3-methylglutaryl-CoA reductase

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2951

Australian pregnancy category D

17 August 2016

pregnancy category

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category X

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category B

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Fluvastatin

5 August 2017

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

C065180

15 March 2018

anticholesteremic agents

1 reference

InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19-/m1/s1

Medical Subject Headings

15 March 2018

Fluvastatin

0 references

Identifiers

InChI

1 reference

fluvastatin (English)

FJLGEFLZQAZZCD-MCBHFWOFSA-N

19 October 2016

InChIKey

2 references

fluvastatin (English)

19 October 2016

ChEBI release 2020-09-01

1 reference

Fluvastatin (English)

4 October 2016

1 reference

fluvastatin (English)

19 October 2016

1 reference

fluvastatin (English)

19 October 2016

Reaxys registry number

8169392

1 reference

(3R,5S)-fluvastatin (English)

19 October 2016

ChEBI ID

38565

mapping relation type

1 reference

(3R,5S)-fluvastatin (English)

19 October 2016

1 reference

MSBNK-Athens_Univ-AU210201

FLUVASTATIN (English)

19 October 2016

1 reference

MassBank accession ID

0 references

MSBNK-Athens_Univ-AU210202

0 references

MSBNK-Athens_Univ-AU210203

0 references

MSBNK-Athens_Univ-AU210204

0 references

MSBNK-Athens_Univ-AU210205

0 references

MSBNK-Athens_Univ-AU210230

0 references

MSBNK-Athens_Univ-AU210231

0 references

MSBNK-Athens_Univ-AU210232

0 references

MSBNK-Athens_Univ-AU210233

0 references

MSBNK-Athens_Univ-AU210251

0 references

MSBNK-Athens_Univ-AU210252

0 references

MSBNK-Athens_Univ-AU210253

0 references

MSBNK-Athens_Univ-AU210254

0 references

MSBNK-Athens_Univ-AU210255

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

0 references

splash10-014i-0091100000-b297dbdceaffa1f61c77

0 references

splash10-00xr-0090000000-f20feb21d04e040bb861

0 references

splash10-00di-0190000000-df9cd2cb219538446a3b

0 references

splash10-00di-0290000000-970d56178cbe49f0fdbe

0 references

splash10-03di-0000900000-1af9c84775c9a0cb149f

0 references

splash10-0002-0009000000-dd585ab6762577836a15

0 references

splash10-03di-0090000000-32fd2a1b25fb2750464e

0 references

splash10-03di-0090000000-4d9916a593869421b7bd

0 references

splash10-03di-0090000000-70757114c6ca0a98b75c

0 references

splash10-03xr-0083900000-c230660de97e8e9ccb73

0 references

splash10-01b9-0090000000-77adc0d8b0debeaa5148

0 references

splash10-00di-0090000000-f62da51bea650786c812

0 references

splash10-00di-0290000000-4a295990449f9a691802

0 references

splash10-00dj-0790000000-ad285c5cd582ee470e8d

0 references

splash10-006t-0970000000-f02d71d5480e038081e5

0 references

splash10-01ot-3009500000-cb8f5859aed5388d9259

0 references

splash10-08g1-6098000000-195d467906fa321c9229

0 references

splash10-03di-3090000000-489ae42f8444b78b1ab2

0 references

splash10-03di-2090000000-f84093216da61f0914d1

0 references

splash10-03di-2090000000-3172307721e6a210a549

0 references

splash10-03di-1090000000-c06231303a3db5397f9b

0 references

HSDB ID

8366

1 reference

Hazardous Substances Data Bank

28 October 2019

Fluvastatin (English)

10 May 2021

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

695-664-7

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.224.327

27 December 2018

ECHA Substance Infocard ID

(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid (English)

quotation

CAS no.: 93957-54-1 (English)

100.224.327

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.224.327

27 December 2018

(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid (English)

quotation

CAS no.: 93957-54-1 (English)

1 reference

World Health Organisation international non-proprietary name numeric ID

Fluvastatin (English)

publication date

17 November 2015

6547

1 reference

https://mednet-communities.net/inn/db/ViewINN.aspx?i=6547

Guide to Pharmacology Ligand ID

2951

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2951

fluvastatin (English)

19 October 2016

Fluvastatin

0 references

0 references

0 references

1 reference

26 February 2018

1 reference

Fluvastatin (English)

4 October 2016

1 reference

Fluvastatin (English)

MedlinePlus drug identifier

4 October 2016

0 references

1 reference

FLUVASTATIN (English)

19 January 2016

0 references

1 reference

electronic Essential Medicines List medicine ID

Fluvastatin (English)

19 January 2016

0 references

1 reference

6 April 2020

0 references

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

1HWI (English)

19 October 2016

0 references

WordNet 3.1 Synset ID

03377502-n

1 reference