miglustat (Q425911)

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chemical compound

N-butyl-1-deoxynojirimycin
NB-DNJ
Zavesca®
SC-48334
n-Butyl deoxynojirimycin
N-Butylmoranoline
N-(n-Butyl)deoxynojirimycin
Butyldeoxynojirimycin
BuDNJ
N-Butyl-1-deoxynojirimycin
N-Butyl deoxynojirimycin
Miglustat
N-(N-Butyl)deoxynojirimycin
NB-dnj
Miglustatum

Language	Label	Description	Also known as
English	miglustat	chemical compound	N-butyl-1-deoxynojirimycin NB-DNJ Zavesca® SC-48334 n-Butyl deoxynojirimycin N-Butylmoranoline N-(n-Butyl)deoxynojirimycin Butyldeoxynojirimycin BuDNJ N-Butyl-1-deoxynojirimycin N-Butyl deoxynojirimycin Miglustat N-(N-Butyl)deoxynojirimycin NB-dnj Miglustatum

Statements

type of chemical entity

0 references

chemical compound

0 references

0 references

chemical structure

Miglustat.png
869 × 1,207; 51 KB

0 references

219.147 dalton

1 reference

language of work or name

Miglustat (English)

19 October 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

chemical formula

C₁₀H₂₁NO₄

1 reference

language of work or name

Miglustat (English)

19 November 2016

canonical SMILES

CCCCN1CC(C(C(C1CO)O)O)O

1 reference

language of work or name

Miglustat (English)

19 November 2016

isomeric SMILES

CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O

1 reference

language of work or name

Miglustat (English)

19 November 2016

defined daily dose

0.3 gram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=A16AX06

active ingredient in

1 reference

14 February 2018

World Health Organisation international non-proprietary name

miglustat (English)

1 reference

language of work or name

miglustat (English)

19 October 2016

medical condition treated

Gaucher's disease

30 July 2003

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/ADN3S497AZ

http://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/21-348_Zavesca_Prntlbl.pdf

physically interacts with

UDP-glucose ceramide glucosyltransferase

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

pregnancy category

US pregnancy category X

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Miglustat

5 March 2018

subject has role

enzyme inhibitor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

anti-HIV agents

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

glycoside hydrolase inhibitors

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

Miglustat-enzyme complex.png
1,280 × 960; 194 KB

0 references

migLUstat

has characteristic

Tall Man lettering

Food and Drug Administration

subject named as

Miglustat

1 reference

https://www.fda.gov/drugs/medication-errors-related-cder-regulated-drug-products/fda-name-differentiation-project

2 September 2022

Commons category

Miglustat

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Identifiers

InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1

1 reference

language of work or name

Miglustat (English)

19 November 2016

UQRORFVVSGFNRO-UTINFBMNSA-N

2 references

language of work or name

Miglustat (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

miglustat (English)

19 November 2016

UQRORFVVSGFNRO-UTINFBMNSA-N

CAS Common Chemistry

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=72599-27-0

1 reference

language of work or name

miglustat (English)

19 November 2016

1 reference

language of work or name

Miglustat (English)

19 November 2016

Reaxys registry number

5862029

1 reference

language of work or name

miglustat (English)

19 October 2016

mapping relation type

1 reference

language of work or name

MIGLUSTAT (English)

19 November 2016

1 reference

language of work or name

MIGLUSTAT (English)

19 November 2016

UniChem compound ID

1 reference

DSSTox substance ID

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

689-232-7

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

(2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol (English)

CAS no.: 72599-27-0 (English)

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

(2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol (English)

CAS no.: 72599-27-0 (English)

1 reference

language of work or name

Miglustat (English)

publication date

17 November 2015

Guide to Pharmacology Ligand ID

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

miglustat (English)

19 November 2016

MeSH descriptor ID

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

Global Substance Registration System

language of work or name

miglustat (English)

19 November 2016

1 reference

language of work or name

Miglustat (English)

19 November 2016

Human Metabolome Database ID

1 reference

based on heuristic

inferred from InChIKey

1 reference

Global Substance Registration System

language of work or name

miglustat (English)

19 November 2016

MedlinePlus drug identifier

0 references

1 reference

Global Substance Registration System

language of work or name

miglustat (English)

19 November 2016

Probes And Drugs ID

0 references

1 reference

1 reference

language of work or name

miglustat (English)

19 October 2016

0 references

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Microsoft Academic ID

0 references

PDB structure ID

1 reference

Protein Data Bank

PDB structure ID

language of work or name

5IEF (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

2V3D (English)

19 October 2016

ScienceDirect topic ID

chemistry/miglustat

0 references

1 reference

Global Substance Registration System

language of work or name

miglustat (English)

19 November 2016

WikiProjectMed ID

0 references

Sitelinks

Wikipedia(8 entries)

dewiki Miglustat
enwiki Miglustat
eswiki Miglustat
fawiki میگلوستات
jawiki ミグルスタット
plwiki Miglustat
shwiki Miglustat
srwiki Miglustat

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Miglustat

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