Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy. (Q48142406)

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English	Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy.	scientific article

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13 March 2020

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Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy (English)

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13 March 2020

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24 March 2019

22 April 2019

17 November 2019

19 November 2019

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17 November 2019

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19 November 2019

James V Hennessey

1

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13 March 2020

author name string

Ramon Espaillat

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30 January 2018

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13 March 2020

International Journal of Clinical Practice

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24 March 2019

22 April 2019

17 November 2019

19 November 2019

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13 March 2020

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13 March 2020

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13 March 2020

copyright license

Creative Commons Attribution-NonCommercial

4 references

24 March 2019

22 April 2019

17 November 2019

19 November 2019

on focus list of Wikimedia project

0 references

Treatment of hypothyroidism with levothyroxine plus liothyronine: a randomized, double-blind, crossover study.

1 reference

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3 July 2018

No Effect of the Thr92Ala Polymorphism of Deiodinase-2 on Thyroid Hormone Parameters, Health-Related Quality of Life, and Cognitive Functioning in a Large Population-Based Cohort Study

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3 July 2018

Is a Normal TSH Synonymous With "Euthyroidism" in Levothyroxine Monotherapy?

1 reference

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3 July 2018

ITALIAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS STATEMENT-REPLACEMENT THERAPY FOR PRIMARY HYPOTHYROIDISM: A BRIEF GUIDE FOR CLINICAL PRACTICE.

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3 July 2018

Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: a 2016 position statement of the Italian Society of Endocrinology and the Italian Thyroid Association

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3 July 2018

Thyroid hormone and its metabolites in relation to quality of life in patients treated for differentiated thyroid cancer.

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3 July 2018

Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters

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3 July 2018

Liothyronine use in a 17 year observational population-based study - the tears study.

1 reference

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3 July 2018

The History and Future of Treatment of Hypothyroidism

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3 July 2018

Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee.

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3 July 2018

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

1 reference

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3 July 2018

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

1 reference

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3 July 2018

Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement

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3 July 2018

Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment

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3 July 2018

2012 ETA Guidelines: The Use of L-T4 + L-T3 in the Treatment of Hypothyroidism

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Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.

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3 July 2018

Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study

1 reference

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3 July 2018

Metabolic effects of liothyronine therapy in hypothyroidism: a randomized, double-blind, crossover trial of liothyronine versus levothyroxine

1 reference

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3 July 2018

Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients

1 reference

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3 July 2018

Do we need still more trials on T4 and T3 combination therapy in hypothyroidism?

1 reference

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3 July 2018

Thyroxine alone or thyroxine plus triiodothyronine replacement therapy for hypothyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination thyroxine plus triiodothyronine therapy in hypothyroid patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Triiodothyronine levels in athyreotic individuals during levothyroxine therapy

1 reference

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3 July 2018

Treatment of clinical hypothyroidism with thyroxine and triiodothyronine: a literature review and metaanalysis.

1 reference

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3 July 2018

Twenty-four hour hormone profiles of TSH, Free T3 and free T4 in hypothyroid patients on combined T3/T4 therapy.

1 reference

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3 July 2018

Thyroxine-triiodothyronine combination therapy versus thyroxine monotherapy for clinical hypothyroidism: meta-analysis of randomized controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3'-triiodothyronine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Substitution of liothyronine at a 1:5 ratio for a portion of levothyroxine: effect on fatigue, symptoms of depression, and working memory versus treatment with levothyroxine alone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Treatment of Hypothyroidism with Combinations of Levothyroxine plus Liothyronine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Thyroid hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone.

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3 July 2018

Partial substitution of thyroxine (T4) with tri-iodothyronine in patients on T4 replacement therapy: results of a large community-based randomized controlled trial.

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3 July 2018

Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14 : 1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism

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3 July 2018

Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Does a combination regimen of thyroxine (T4) and 3,5,3'-triiodothyronine improve depressive symptoms better than T4 alone in patients with hypothyroidism? Results of a double-blind, randomized, controlled trial

1 reference

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3 July 2018

Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: a randomized controlled trial in patients with primary hypothyroidism

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3 July 2018

Thyroxine vs thyroxine plus triiodothyronine in treatment of hypothyroidism after thyroidectomy for Graves' disease

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3 July 2018

Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III).

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1 December 2018

The Colorado thyroid disease prevalence study

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3 July 2018

Effects of thyroxine as compared with thyroxine plus triiodothyronine in patients with hypothyroidism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Do traditional symptoms of hypothyroidism correlate with biochemical disease?

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3 July 2018

Total and free thyroid hormone concentrations in patients receiving maintenance replacement treatment with thyroxine.

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3 July 2018

Conversion of Thyroxine (T4) to triiodothyronine (T3) in athyreotic human subjects

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

3 July 2018

Determination of Iodothyronine Absorption and Conversion of L-Thyroxine (T4) to L-Triiodothyronine (T3) using Turnover Rate Techniques

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3 July 2018

Simultaneous measurement of thyroxine and triiodothyronine peripheral turnover kinetics in man.

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3 July 2018

L-thyroxine dosage: a reevaluation of therapy with contemporary preparations

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3 July 2018

A 2013 survey of clinical practice patterns in the management of primary hypothyroidism

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14 August 2018

Thyroxine and triiodothyronine content in commercially available thyroid health supplements

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14 August 2018

Combined therapy with L-thyroxine and L-triiodothyronine compared to L-thyroxine alone in the treatment of primary hypothyroidism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Efficacy of combined levothyroxine and liothyronine as compared with levothyroxine monotherapy in primary hypothyroidism: a randomized controlled trial.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Effect of combination therapy with thyroxine (T4) and 3,5,3'-triiodothyronine versus T4 monotherapy in patients with hypothyroidism, a double-blind, randomised cross-over study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Health status, psychological symptoms, mood, and cognition in L-thyroxine-treated hypothyroid subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Psychological well-being correlates with free thyroxine but not free 3,5,3'-triiodothyronine levels in patients on thyroid hormone replacement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Cognitive functioning and well-being in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Thyrotoxicosis caused by weight-reducing herbal medicines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Combined therapy with levothyroxine and liothyronine in two ratios, compared with levothyroxine monotherapy in primary hypothyroidism: a double-blind, randomized, controlled clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Psychological well-being of patients on L-thyroxine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Psychological well-being in patients on 'adequate' doses of l-thyroxine: results of a large, controlled community-based questionnaire study.

1 reference

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14 August 2018

Mental improvement after replacement therapy with thyroxine plus triiodothyronine: relationship to cause of hypothyroidism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5873391

14 August 2018

Free thyroxine, free triiodothyronine, and thyrotropin concentrations in hypothyroid and thyroid carcinoma patients receiving thyroxine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled clinical trial of combined triiodothyronine and thyroxine in the treatment of hypothyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid and clinical response to a new thyroid hormone combination

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined Thyroxine and Triiodothyronine for Thyroid Replacement Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of Thyroxine and Triiodothyronine in Commercial Preparations of Desiccated Thyroid and Thyroid Extract

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The incidence and prevalence of thyroid dysfunction in Europe: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-State Serum T3 Concentrations for 48 Hours Following the Oral Administration of a Single Dose of 3,5,3'-Triiodothyronine Sulfate (T3S)

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON THYROID DYSFUNCTION CASE FINDING

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

There is no 'universal fit': Reflections on the use of l-triiodothyronine in the treatment of hypothyroidism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29381251

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/IJCP.13062

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29381251%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29381251%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

Europe PubMed Central

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13 March 2020

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