New insights into ANGPLT3 in controlling lipoprotein metabolism and risk of cardiovascular diseases. (Q50044216)

24 February 2018

1 reference

4 August 2022

New insights into ANGPLT3 in controlling lipoprotein metabolism and risk of cardiovascular diseases. (English)

1 reference

24 February 2018

angiopoietin-like proteins

main subject

cardiovascular disease

1 reference

6 November 2020

1 reference

8 August 2019

1 reference

13 November 2019

1 reference

19 November 2019

1 reference

6 November 2020

ANGPTL3

1 reference

Xin Su

1

1 reference

24 February 2018

Dao-Quan Peng

series ordinal

2

1 reference

24 February 2018

language of work or name

1 reference

15 January 2018

9 references

24 February 2018

Lipids in Health and Disease

24 March 2019

17 June 2019

8 August 2019

13 November 2019

19 November 2019

20 November 2019

6 November 2020

4 August 2022

9 references

24 February 2018

24 March 2019

17 June 2019

8 August 2019

13 November 2019

19 November 2019

20 November 2019

6 November 2020

4 August 2022

17

1 reference

24 February 2018

page(s)

12

1 reference

24 February 2018

issue

1

1 reference

24 February 2018

Creative Commons Attribution 4.0 International

copyright license

8 references

24 March 2019

17 June 2019

8 August 2019

13 November 2019

19 November 2019

20 November 2019

6 November 2020

on focus list of Wikimedia project

4 August 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12944-018-0659-y

0 references

cites work

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

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ANGPLT3: A novel modulator of lipid metabolism

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Apoc-III antisense oligonucleotides: a new option for the treatment of hypertriglyceridemia

22 May 2018

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ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance

22 May 2018

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ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

22 May 2018

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Medical and psychosocial factors and unfavourable low-density lipoprotein cholesterol control in coronary patients

22 May 2018

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Dietary Strategies Implicated in the Prevention and Treatment of Metabolic Syndrome

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Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey

22 May 2018

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ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.

22 May 2018

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Low-Density Lipoprotein Receptor Signaling Mediates the Triglyceride-Lowering Action of Akkermansia muciniphila in Genetic-Induced Hyperlipidemia.

22 May 2018

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Discontinuation of Statins: What Are the Risks?

22 May 2018

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The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking

22 May 2018

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Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism

22 May 2018

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Regulation of lipid metabolism by angiopoietin-like proteins

22 May 2018

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The role of ANGPTL3 in controlling lipoprotein metabolism

22 May 2018

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Update on the molecular biology of dyslipidemias

22 May 2018

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Hepatic ANGPTL3 regulates adipose tissue energy homeostasis

22 May 2018

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Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis

22 May 2018

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Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin

22 May 2018

1 reference

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Liver X receptors at the intersection of lipid metabolism and atherogenesis

22 May 2018

1 reference

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Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion

22 May 2018

1 reference

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Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation

22 May 2018

1 reference

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Lipoprotein lipase: from gene to atherosclerosis

22 May 2018

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CETP inhibitors downregulate hepatic LDL receptor and PCSK9 expression in vitro and in vivo through a SREBP2 dependent mechanism.

22 May 2018

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Triglyceride-raising APOA5 genetic variants are associated with obesity and non-HDL-C in Chinese children and adolescents

22 May 2018

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Statin and the risk of renal-related serious adverse events: Analysis from the IDEAL, TNT, CARDS, ASPEN, SPARCL, and other placebo-controlled trials

22 May 2018

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Hypobetalipoproteinemia and abetalipoproteinemia

22 May 2018

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Adipocyte triglyceride turnover and lipolysis in lean and overweight subjects.

22 May 2018

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Dietary alleviation of maternal obesity and diabetes: increased resistance to diet-induced obesity transcriptional and epigenetic signatures

22 May 2018

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Emerging roles of Lipasin as a critical lipid regulator

22 May 2018

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Liver X Receptors and female reproduction: when cholesterol meets fertility!

22 May 2018

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Atypical angiopoietin-like protein that regulates ANGPTL3

22 May 2018

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JUPITER and satellites: Clinical implications of the JUPITER study and its secondary analyses

22 May 2018

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Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia

22 May 2018

1 reference

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Biological, clinical and population relevance of 95 loci for blood lipids

22 May 2018

1 reference

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Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases

22 May 2018

1 reference

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GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

A highly conserved motif within the NH2-terminal coiled-coil domain of angiopoietin-like protein 4 confers its inhibitory effects on lipoprotein lipase by disrupting the enzyme dimerization.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase

22 May 2018

1 reference

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Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells.

22 May 2018

1 reference

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Differential regulation and properties of angiopoietin-like proteins 3 and 4

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Type 2 diabetes, cardiovascular risk, and the link to insulin resistance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angptl3 regulates lipid metabolism in mice

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Identification of a mammalian angiopoietin-related protein expressed specifically in liver

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angiopoietin-like 3 in lipoprotein metabolism.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Cardiovascular safety and efficacy of the PCSK9 inhibitor evolocumab in patients with and without diabetes and the effect of evolocumab on glycaemia and risk of new-onset diabetes: a prespecified analysis of the FOURIER randomised controlled trial.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Evaluating the Effectiveness of New York City Health Policy Initiatives in Reducing Cardiovascular Disease Mortality, 1990-2011.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Use of next-generation sequencing to detect LDLR gene copy number variation in familial hypercholesterolemia

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angiopoietin-like protein 3 and 4 expression 4 and their serum levels in hepatocellular carcinoma

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Homozygous familial hypercholesterolemia: Summarized case reports.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

The majority of lipoprotein lipase in plasma is bound to remnant lipoproteins: A new definition of remnant lipoproteins

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Atheroma progression in hyporesponders to statin therapy.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

A novel role of angiopoietin-like-3 associated with podocyte injury.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Functional variants of lipid level modifier MLXIPL, GCKR, GALNT2, CILP2, ANGPTL3 and TRIB1 genes in healthy Roma and Hungarian populations.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Short- and long-term effects of xuezhikang, an extract of cholestin, on serum proprotein convertase subtilisin/kexin type 9 levels

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Short-term impact of low-dose atorvastatin on serum proprotein convertase subtilisin/kexin type 9.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Angptl3 deficiency is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Induction of ABCA1 and ABCG1 expression by the liver X receptor modulator cineole in macrophages.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Rationale and design of China intensive lipid lowering with statins in acute coronary syndrome: the CHILLAS study

14 August 2018

1 reference

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Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5769531

Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study

14 August 2018

1 reference

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Comparative integromics on Angiopoietin family members.

14 August 2018

1 reference

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Characterization of the lipolytic activity of endothelial lipase

14 August 2018

1 reference

12 December 2020

Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity

1 reference

12 December 2020

Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance

1 reference

12 December 2020

Effects of high-dose statin on the human hepatic expression of genes involved in carbohydrate and triglyceride metabolism

1 reference

12 December 2020

Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4

1 reference

12 December 2020

The effect of moderate-dose versus double-dose statins on patients with acute coronary syndrome in China: Results of the CHILLAS trial

1 reference

12 December 2020

10.1186/S12944-018-0659-Y

Identifiers

DOI

1 reference

24 February 2018

Dimensions Publication ID

0 references

1 reference

24 February 2018

PubMed ID

29334984

1 reference

24 February 2018