Alternative mRNA Splicing in the Pathogenesis of Obesity. (Q54971907)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

review article

0 references

title

Alternative mRNA Splicing in the Pathogenesis of Obesity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

3 references

19 March 2019

24 March 2019

8 September 2019

regulation of gene expression

1 reference

8 September 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

author name string

Lu Xu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Mabel Yin-Chun Yau

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

language of work or name

English

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publication date

23 February 2018

4 references

19 March 2019

24 March 2019

8 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Molecular Sciences

18 March 2020

published in

4 references

19 March 2019

24 March 2019

8 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

19

1 reference

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18 March 2020

issue

2

1 reference

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Creative Commons Attribution

18 March 2020

copyright license

3 references

19 March 2019

24 March 2019

8 September 2019

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on focus list of Wikimedia project

ScienceSource

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Regulation of SMN protein stability

14 June 2018

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SRp20 and CUG-BP1 modulate insulin receptor exon 11 alternative splicing

14 June 2018

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Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology

14 June 2018

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Alternative splicing and disease

14 June 2018

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Alternative splicing of mRNA as a mode of endocrine regulation

14 June 2018

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Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance

14 June 2018

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The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C

14 June 2018

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Lipin, a lipodystrophy and obesity gene

14 June 2018

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Natural history of denervation in SMA: relation to age, SMN2 copy number, and function

14 June 2018

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Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin

14 June 2018

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How do mutations in lamins A and C cause disease?

14 June 2018

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Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors

14 June 2018

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The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Abnormal fatty acid metabolism in childhood spinal muscular atrophy

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Chronic primary hyperinsulinaemia is associated with altered insulin receptor mRNA splicing in muscle of patients with insulinoma

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Abnormal splicing of the leptin receptor in diabetic mice

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Fatty acid oxidation abnormalities in childhood-onset spinal muscular atrophy: primary or secondary defect(s)?

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Altered expression of insulin receptor types A and B in the skeletal muscle of non-insulin-dependent diabetes mellitus patients

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

The mechanisms of action of metformin

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Pharmacology of Modulators of Alternative Splicing

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

RBFOX2 protein domains and cellular activities.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Fox-1 family of RNA-binding proteins

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Environmental perturbations lead to extensive directional shifts in RNA processing.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Insulin Receptor Isoforms in Physiology and Disease: An Updated View.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Nusinersen: antisense oligonucleotide to increase SMN protein production in spinal muscular atrophy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Nusinersen: The First Option Beyond Supportive Care for Spinal Muscular Atrophy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Htr2c Splice Variants and 5HT2CR-Mediated Appetite.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

SIRT1 and SIRT7 expression in adipose tissues of obese and normal-weight individuals is regulated by microRNAs but not by methylation status.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 study

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

RNA splicing and editing modulation of 5-HT(2C) receptor function: relevance to anxiety and aggression in VGV mice.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Leptin and soluble leptin receptor levels in obese and weight-losing individuals.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Altered insulin receptor messenger ribonucleic acid splicing in liver is associated with deterioration of glucose tolerance in the spontaneously obese and diabetic rhesus monkey: analysis of controversy between monkey and human studies.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Insulin-inducible changes in insulin receptor mRNA splice variants.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5855854

Description of a new model of genetic obesity: the dbPas mouse

13 August 2018

1 reference

12 December 2020

A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron

1 reference

12 December 2020

Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation

1 reference

12 December 2020

LMNA mRNA expression is altered in human obesity and type 2 diabetes

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS19020632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29473878%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference