Malaria Vaccines: Recent Advances and New Horizons (Q56362064)

6

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Simon J. Draper

object named as

Simon J Draper

1

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Carole A Long

7

object named as

Carole A Long

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author name string

Brandon K Sack

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C Richter King

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Carolyn M Nielsen

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Robert A Seder

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

11 July 2018

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23 March 2019

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30 June 2019

22 October 2019

28 May 2020

3 September 2020

18 July 2021

3 October 2022

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23 March 2019

20 June 2019

30 June 2019

22 October 2019

28 May 2020

3 September 2020

18 July 2021

3 October 2022

24

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page(s)

43-56

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issue

1

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copyright license

8 references

23 March 2019

20 June 2019

30 June 2019

22 October 2019

28 May 2020

3 September 2020

18 July 2021

on focus list of Wikimedia project

3 October 2022

ScienceSource

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cites work

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A Plasmodium parasite with complete late liver stage arrest protects against pre-erythrocytic and erythrocytic stage infection in mice.

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Immunization of malaria pre-exposed volunteers with PfSPZ Vaccine elicits long-lived IgM invasion-inhibitory and complement-fixing antibodies.

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29 September 2018

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Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.

29 September 2018

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Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions.

29 September 2018

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γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations.

29 September 2018

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Synergistic malaria vaccine combinations identified by systematic antigen screening

29 September 2018

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Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

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29 September 2018

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Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

29 September 2018

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A malaria vaccine protects Aotus monkeys against virulent Plasmodium falciparum infection

29 September 2018

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Evaluation of two lead malaria transmission blocking vaccine candidate antibodies in natural parasite-vector combinations.

29 September 2018

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Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

29 September 2018

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Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.

29 September 2018

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Liposomes containing monophosphoryl lipid A and QS-21 serve as an effective adjuvant for soluble circumsporozoite protein malaria vaccine FMP013.

29 September 2018

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Chemical Attenuation in the Development of a Whole-Organism Malaria Vaccine

29 September 2018

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Dual Plug-and-Display Synthetic Assembly Using Orthogonal Reactive Proteins for Twin Antigen Immunization

29 September 2018

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29 September 2018

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29 September 2018

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Rational development of a protective P. vivax vaccine evaluated with transgenic rodent parasite challenge models

29 September 2018

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Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate

29 September 2018

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Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

29 September 2018

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Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial.

29 September 2018

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Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

29 September 2018

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Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

29 September 2018

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P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

29 September 2018

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What Are the Most Powerful Immunogen Design Vaccine Strategies?

29 September 2018

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Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

29 September 2018

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Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.

29 September 2018

1 reference

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Theoretical Implications of a Pre-Erythrocytic Plasmodium vivax Vaccine for Preventing Relapses

29 September 2018

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Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects

29 September 2018

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Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine

29 September 2018

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Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal.

29 September 2018

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Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential.

29 September 2018

1 reference

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Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications

29 September 2018

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Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study

29 September 2018

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Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial

29 September 2018

1 reference

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Safety and Immunogenicity of Pfs25-EPA/Alhydrogel®, a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naïve Adults

29 September 2018

1 reference

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Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

29 September 2018

1 reference

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Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.

29 September 2018

1 reference

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Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes

29 September 2018

1 reference

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Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

29 September 2018

1 reference

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Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP.

29 September 2018

1 reference

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Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study

29 September 2018

1 reference

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Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

29 September 2018

1 reference

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Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

RTS,S Malaria Vaccine and Increased Mortality in Girls

29 September 2018

1 reference

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Discriminating Protective from Nonprotective Plasmodium-Specific CD8+ T Cell Responses

29 September 2018

1 reference

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Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy

29 September 2018

1 reference

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Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01

29 September 2018

1 reference

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Malaria vaccine: WHO position paper-January 2016

29 September 2018

1 reference

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Overlaying Molecular and Temporal Aspects of Malaria Parasite Invasion

29 September 2018

1 reference

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Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

29 September 2018

1 reference

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Progress with viral vectored malaria vaccines: A multi-stage approach involving "unnatural immunity".

29 September 2018

1 reference

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Recent advances in recombinant protein-based malaria vaccines

29 September 2018

1 reference

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Malaria vaccines: identifying Plasmodium falciparum liver-stage targets

29 September 2018

1 reference

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Large screen approaches to identify novel malaria vaccine candidates

29 September 2018

1 reference

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Development of vaccines for Plasmodium vivax malaria

29 September 2018

1 reference

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Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

29 September 2018

1 reference

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Basigin is a druggable target for host-oriented antimalarial interventions

29 September 2018

1 reference

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Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Targeting Human Transmission Biology for Malaria Elimination

29 September 2018

1 reference

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Comparative assessment of transmission-blocking vaccine candidates against Plasmodium falciparum

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design

29 September 2018

1 reference

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Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies

29 September 2018

1 reference

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A sufficient role of MHC class I molecules on hepatocytes in anti-plasmodial activity of CD8 (+) T cells in vivo

29 September 2018

1 reference

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A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys

29 September 2018

1 reference

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Multiprotein complex between the GPI-anchored CyRPA with PfRH5 and PfRipr is crucial for Plasmodium falciparum erythrocyte invasion

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Antigen export during liver infection of the malaria parasite augments protective immunity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Correlates of protective immunity following whole sporozoite vaccination against malaria

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

De novo assembly of a field isolate genome reveals novel Plasmodium vivax erythrocyte invasion genes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Malaria vaccine technology roadmap

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Comparison of the immune responses induced by soluble and particulate Plasmodium vivax circumsporozoite vaccine candidates formulated in AS01 in rhesus macaques

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

The human malaria parasite Pfs47 gene mediates evasion of the mosquito immune system

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticle

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Red blood cell polymorphism and susceptibility to Plasmodium vivax

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Vaccination with Plasmodium knowlesi AMA1 formulated in the novel adjuvant co-vaccine HT™ protects against blood-stage challenge in rhesus macaques

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

The IC(50) of anti-Pfs25 antibody in membrane-feeding assay varies among species

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Immunity to recombinant plasmodium falciparum merozoite surface protein 1 (MSP1): protection in Aotus nancymai monkeys strongly correlates with anti-MSP1 antibody titer and in vitro parasite-inhibitory activity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6054918

Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

29 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30001524

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30001524

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30001524