Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria (Q58566399)

8

object named as

Rob Hooft van Huijsduijnen

0 references

Jeremy Burrows

3

object named as

Jeremy N Burrows

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author name string

Fiona Macintyre

1

0 references

Hanu Ramachandruni

2

0 references

René Holm

4

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Anna Thomas

5

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Jörg J Möhrle

6

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Stephan Duparc

7

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Winston E Gutteridge

10

0 references

Timothy N C Wells

11

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Wiweka Kaszubska

Creative Commons Attribution 4.0 International

12

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language of work or name

English

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publication date

1 November 2018

8 references

23 March 2019

20 June 2019

22 June 2019

25 June 2019

19 September 2019

18 July 2021

22 August 2022

3 October 2022

8 references

23 March 2019

20 June 2019

22 June 2019

25 June 2019

19 September 2019

18 July 2021

22 August 2022

3 October 2022

17

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page(s)

402

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issue

1

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copyright license

8 references

23 March 2019

20 June 2019

22 June 2019

25 June 2019

19 September 2019

18 July 2021

22 August 2022

on focus list of Wikimedia project

3 October 2022

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/s12936-018-2549-1

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30 November 2018

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Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers

30 November 2018

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Progress with the PfSPZ Vaccine for malaria

30 November 2018

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New developments in anti-malarial target candidate and product profiles

30 November 2018

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Does antimalarial mass drug administration increase or decrease the risk of resistance?

30 November 2018

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Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria

30 November 2018

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Effectiveness of twice a week prophylaxis with atovaquone-proguanil (Malarone®) in long-term travellers to West Africa

30 November 2018

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Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes

30 November 2018

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Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa

30 November 2018

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Monoclonal antibody therapies for the treatment of relapsing-remitting multiple sclerosis: differentiating mechanisms and clinical outcomes

30 November 2018

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Pharmacokinetics of monoclonal antibodies used for inflammatory bowel diseases in pregnant women.

30 November 2018

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HIV pre-exposure prophylaxis (PrEP): a review of current knowledge of oral systemic HIV PrEP in humans

30 November 2018

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Hit and lead criteria in drug discovery for infectious diseases of the developing world

30 November 2018

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Malaria kills more than Ebola virus disease

30 November 2018

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30 November 2018

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A novel multiple-stage antimalarial agent that inhibits protein synthesis

30 November 2018

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Long-acting antiviral agents for HIV treatment

30 November 2018

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Malaria medicines: a glass half full?

30 November 2018

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Across-Species Scaling of Monoclonal Antibody Pharmacokinetics Using a Minimal PBPK Model

30 November 2018

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Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: a modelling analysis.

30 November 2018

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Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies

30 November 2018

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The history of monoclonal antibody development - Progress, remaining challenges and future innovations

30 November 2018

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Antibody and B cell responses to Plasmodium sporozoites

30 November 2018

1 reference

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Asymptomatic malaria infections: detectability, transmissibility and public health relevance

30 November 2018

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Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites

30 November 2018

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KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

30 November 2018

1 reference

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Mechanistic considerations for the use of monoclonal antibodies for cancer therapy.

30 November 2018

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Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections

30 November 2018

1 reference

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Clinical development success rates for investigational drugs

30 November 2018

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Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

30 November 2018

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Long-acting injectable antiretrovirals for HIV treatment and prevention

30 November 2018

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Are monoclonal antibodies a safe treatment for cancer during pregnancy?

30 November 2018

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The open access malaria box: a drug discovery catalyst for neglected diseases

30 November 2018

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Factors influencing magnitude and duration of target inhibition following antibody therapy: implications in drug discovery and development

30 November 2018

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30 November 2018

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Effectiveness of Long-Acting Reversible Contraception

30 November 2018

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Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug

30 November 2018

1 reference

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Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

30 November 2018

1 reference

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Strategies for extended serum half-life of protein therapeutics

30 November 2018

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Doxycycline for malaria chemoprophylaxis and treatment: report from the CDC expert meeting on malaria chemoprophylaxis

30 November 2018

1 reference

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Properties of a general PK/PD model of antibody-ligand interactions for therapeutic antibodies that bind to soluble endogenous targets

30 November 2018

1 reference

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Chemical genetics of Plasmodium falciparum

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Thousands of chemical starting points for antimalarial lead identification

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Industrialization of mAb production technology: the bioprocessing industry at a crossroads

30 November 2018

1 reference

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An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies

30 November 2018

1 reference

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Strategies to extend plasma half-lives of recombinant antibodies

30 November 2018

1 reference

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Acquired immunity to malaria

30 November 2018

1 reference

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

A systematic review and meta-analysis of the effectiveness and safety of atovaquone proguanil (Malarone) for chemoprophylaxis against malaria

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone-proguanil (malarone): an effective treatment for uncomplicated Plasmodium falciparum malaria in travelers from Denmark.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in nonimmune pediatric travelers: results of an international, randomized, open-label study

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Solubilizing excipients in oral and injectable formulations

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

LABORATORY STUDIES ON THE REPOSITORY ANTIMALARIAL ACTIVITY OF 4,4'-DIACETYLAMINODIPHENYLSULFONE, ALONE AND MIXED WITH CYCLOGUANIL PAMOATE (CI-501).

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Gamma-globulin and acquired immunity to human malaria.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone-proguanil for prophylaxis and treatment of malaria.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone/proguanil: a review of its use for the prophylaxis of Plasmodium falciparum malaria

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in non-immune travellers: a randomised, double-blind study. Malarone International Study Team

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Activities of respository preparations of cycloguanil pamoate and 4,4'-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Antimalarial activity of mefloquine and qinghaosu

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Field trials of repository antimalarial compounds

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Enhancement or inhibition of Plasmodium falciparum erythrocyte reinvasion in vitro by antibodies to an asparagine rich protein

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Studies on a new antimalarial compound: pyronaridine

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

A protective monoclonal antibody with dual specificity for Plasmodium falciparum and Plasmodium berghei circumsporozoite proteins.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6211409

Treatment of cancer during pregnancy with monoclonal antibodies: a real challenge

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30384848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches - a PEARRL review

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30384848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasmodium falciparum In Vitro Culture - The Highs and Lows

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30384848