US28: HCMV's Swiss Army Knife (Q58734495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

2 references

14 July 2021

22 August 2022

US28: HCMV's Swiss Army Knife (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

main subject

cardiovascular disease

1 reference

host-pathogen interaction

24 August 2020

cytomegaloviral disease

2 references

14 July 2021

22 August 2022

1 reference

3 November 2019

1 reference

23 December 2019

1 reference

viral gene expression regulation

27 July 2020

1 reference

24 August 2020

1 reference

8 February 2021

chemokine receptor family

1 reference

14 July 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

William E Miller

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Christine M O'Connor

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

author name string

Benjamin A Krishna

1

0 references

William E Miller

2

0 references

Christine M O'Connor

3

0 references

language of work or name

English

0 references

publication date

20 August 2018

16 references

23 March 2019

3 April 2019

20 June 2019

17 June 2019

31 July 2019

8 September 2019

21 October 2019

3 November 2019

15 December 2019

23 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

27 July 2020

24 August 2020

8 February 2021

14 July 2021

22 August 2022

16 references

23 March 2019

3 April 2019

20 June 2019

17 June 2019

31 July 2019

8 September 2019

21 October 2019

3 November 2019

15 December 2019

23 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

27 July 2020

24 August 2020

8 February 2021

14 July 2021

22 August 2022

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

page(s)

445

0 references

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

19 April 2020

copyright license

15 references

23 March 2019

3 April 2019

20 June 2019

17 June 2019

31 July 2019

8 September 2019

21 October 2019

3 November 2019

15 December 2019

23 December 2019

27 July 2020

24 August 2020

8 February 2021

14 July 2021

22 August 2022

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

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The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth.

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Human Cytomegalovirus UL111A and US27 gene products enhance the CXCL12/CXCR4 signaling axis via distinct mechanisms.

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Oncogenic role of cytomegalovirus in medulloblastoma?

30 November 2018

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Cytomegalovirus Infection and Relative Risk of Cardiovascular Disease (Ischemic Heart Disease, Stroke, and Cardiovascular Death): A Meta-Analysis of Prospective Studies Up to 2016.

30 November 2018

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Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein.

30 November 2018

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Human Cytomegalovirus (HCMV)-Specific CD4+ T Cells Are Polyfunctional and Can Respond to HCMV-Infected Dendritic Cells In Vitro

30 November 2018

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US28, a Virally-Encoded GPCR as an Antiviral Target for Human Cytomegalovirus Infection

30 November 2018

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Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28.

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Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells.

30 November 2018

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The HCMV US28 vGPCR induces potent Gαq/PLC-β signaling in monocytes leading to increased adhesion to endothelial cells.

30 November 2018

1 reference

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Cytomegalovirus Restructures Lipid Rafts via a US28/CDC42-Mediated Pathway, Enhancing Cholesterol Efflux from Host Cells

30 November 2018

1 reference

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Human Cytomegalovirus is Present in Alveolar Soft Part Sarcoma.

30 November 2018

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Human cytomegalovirus-encoded US28 may act as a tumor promoter in colorectal cancer

30 November 2018

1 reference

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Valganciclovir and bevacizumab for recurrent glioblastoma: A single-institution experience

30 November 2018

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Congenital Cytomegalovirus

30 November 2018

1 reference

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Expression of cytomegalovirus in glioblastoma multiforme: Myth or reality?

30 November 2018

1 reference

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Human Cytomegalovirus US28 Is Important for Latent Infection of Hematopoietic Progenitor Cells

30 November 2018

1 reference

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Cytomegalovirus latency and reactivation: recent insights into an age old problem

30 November 2018

1 reference

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Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo

30 November 2018

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30 November 2018

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Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)-Seropositive Individuals Are Sites of HCMV Reactivation In Vivo

30 November 2018

1 reference

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The oncogenic potential of human cytomegalovirus and breast cancer

30 November 2018

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Human cytomegalovirus infection in tumor cells of the nervous system is not detectable with standardized pathologico-virological diagnostics.

30 November 2018

1 reference

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The M33 G protein-coupled receptor encoded by murine cytomegalovirus is dispensable for hematogenous dissemination but is required for growth within the salivary gland

30 November 2018

1 reference

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GPCR structures in drug design, emerging opportunities with new structures

30 November 2018

1 reference

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Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists?

30 November 2018

1 reference

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Absence of cytomegalovirus in high-coverage DNA sequencing of human glioblastoma multiforme.

30 November 2018

1 reference

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Cytomegalovirus and glioma: putting the cart before the horse

30 November 2018

1 reference

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Human cytomegalovirus US28 facilitates cell-to-cell viral dissemination

30 November 2018

1 reference

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Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?

30 November 2018

1 reference

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Synthesis and biological evaluation of biphenyl amides that modulate the US28 receptor

30 November 2018

1 reference

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Valganciclovir in patients with glioblastoma

30 November 2018

1 reference

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High prevalence of HCMV and viral load in tumor tissues and peripheral blood of glioblastoma multiforme patients

30 November 2018

1 reference

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Gammaherpesviruses and lymphoproliferative disorders

30 November 2018

1 reference

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The landscape of viral expression and host gene fusion and adaptation in human cancer

30 November 2018

1 reference

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Survival in patients with glioblastoma receiving valganciclovir

30 November 2018

1 reference

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Development of flavonoid-based inverse agonists of the key signaling receptor US28 of human cytomegalovirus

30 November 2018

1 reference

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Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations.

30 November 2018

1 reference

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Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells

30 November 2018

1 reference

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The US27 gene product of human cytomegalovirus enhances signaling of host chemokine receptor CXCR4.

30 November 2018

1 reference

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Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: a randomized, double-blind, hypothesis-generating study

30 November 2018

1 reference

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The myeloid transcription factor GATA-2 regulates the viral UL144 gene during human cytomegalovirus latency in an isolate-specific manner

30 November 2018

1 reference

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Non-traditional roles of G protein-coupled receptors in basic cell biology

30 November 2018

1 reference

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US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells

30 November 2018

1 reference

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Constitutive β-catenin signaling by the viral chemokine receptor US28

30 November 2018

1 reference

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Human cytomegalovirus pUL78 G protein-coupled receptor homologue is required for timely cell entry in epithelial cells but not fibroblasts

30 November 2018

1 reference

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Genetic analysis of cytomegalovirus in malignant gliomas

30 November 2018

1 reference

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Low levels of Human Cytomegalovirus Infection in Glioblastoma multiforme associates with patient survival; -a case-control study

30 November 2018

1 reference

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Consensus on the role of human cytomegalovirus in glioblastoma

30 November 2018

1 reference

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Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target

30 November 2018

1 reference

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Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype

30 November 2018

1 reference

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OPM database and PPM web server: resources for positioning of proteins in membranes

30 November 2018

1 reference

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Heteromerization of human cytomegalovirus encoded chemokine receptors

30 November 2018

1 reference

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Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype

30 November 2018

1 reference

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Human cytomegalovirus pUS27 G protein-coupled receptor homologue is required for efficient spread by the extracellular route but not for direct cell-to-cell spread

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Oncomodulation by human cytomegalovirus: novel clinical findings open new roads

30 November 2018

1 reference

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HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients

30 November 2018

1 reference

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Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28.

30 November 2018

1 reference

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Human cytomegalovirus-encoded chemokine receptor homolog US28 stimulates the major immediate early gene promoter/enhancer via the induction of CREB.

30 November 2018

1 reference

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Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

30 November 2018

1 reference

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The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human Cytomegalovirus US28: a functionally selective chemokine binding receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The M33 chemokine receptor homolog of murine cytomegalovirus exhibits a differential tissue-specific role during in vivo replication and latency.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Differential ligand binding to a human cytomegalovirus chemokine receptor determines cell type-specific motility

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Oncomodulation by human cytomegalovirus: evidence becomes stronger.

30 November 2018

1 reference

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Atherosclerotic plaque development and instability: a dual role for VEGF.

30 November 2018

1 reference

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The Gq and G12 families of heterotrimeric G proteins report functional selectivity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Inflammation at the molecular interface of atherogenesis: an anthropological journey

30 November 2018

1 reference

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Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Antiviral strategies to combat cytomegalovirus infections in transplant recipients

30 November 2018

1 reference

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Mechanisms of cytomegalovirus-accelerated vascular disease: induction of paracrine factors that promote angiogenesis and wound healing

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Constitutive serum response factor activation by the viral chemokine receptor homologue pUS28 is differentially regulated by Galpha(q/11) and Galpha(16).

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Haplotype-specific expression of the human PDGFRA gene correlates with the risk of glioblastomas.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus secretome contains factors that induce angiogenesis and wound healing

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Detection of human cytomegalovirus in different histological types of gliomas

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Agonist-selective mechanisms of GPCR desensitization

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The 2007 WHO classification of tumours of the central nervous system

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The chemokine network. I. How the genomic organization of chemokines contains clues for deciphering their functional complexity.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

G protein-coupled receptor (GPCR) kinase 2 regulates agonist-independent Gq/11 signaling from the mouse cytomegalovirus GPCR M33.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Viral gene expression during the establishment of human cytomegalovirus latent infection in myeloid progenitor cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Synthesis and pharmacological characterization of novel inverse agonists acting on the viral-encoded chemokine receptor US28.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer?

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The human cytomegalovirus-encoded receptor US28 increases the activity of the major immediate-early promoter/enhancer

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Differential activation of G-proteins by mu-opioid receptor agonists

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Molecular mechanism of 7TM receptor activation--a global toggle switch model

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Chemokine scavenging by the human cytomegalovirus chemokine decoy receptor US28 does not inhibit monocyte adherence to activated endothelium

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

HCMV-encoded G-protein-coupled receptors as constitutively active modulators of cellular signaling networks

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Synthesis and structure-activity relationship of the first nonpeptidergic inverse agonists for the human cytomegalovirus encoded chemokine receptor US28.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Heterodimerization of g protein-coupled receptors: specificity and functional significance.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The human cytomegalovirus UL78 gene is highly conserved among clinical isolates, but is dispensable for replication in fibroblasts and a renal artery organ-culture system

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Chemokine-receptor interactions: GPCRs, glycosaminoglycans and viral chemokine binding proteins

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

UCSF Chimera--a visualization system for exploratory research and analysis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

G protein-coupled receptor dimerization: function and ligand pharmacology

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Differential outcomes of human cytomegalovirus infection in primitive hematopoietic cell subpopulations

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

G protein signaling: insights from new structures.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Functional profiling of a human cytomegalovirus genome

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Constitutively active Gq/11-coupled Receptors Enable Signaling by Co-expressed Gi/o-coupled Receptors

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human Cytomegalovirus Chemokine Receptor US28-induced Smooth Muscle Cell Migration Is Mediated by Focal Adhesion Kinase and Src

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Constitutive inositol phosphate formation in cytomegalovirus-infected human fibroblasts is due to expression of the chemokine receptor homologue pUS28.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Viral mimicry of cytokines, chemokines and their receptors

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Surface expression and endocytosis of the human cytomegalovirus-encoded chemokine receptor US28 is regulated by agonist-independent phosphorylation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Murine cytomegalovirus (CMV) M33 and human CMV US28 receptors exhibit similar constitutive signaling activities

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus infection and expression in human malignant glioma.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus in neoplastic cells of Epstein-Barr virus negative Hodgkin's disease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

International Union of Pharmacology. XXX. Update on chemokine receptor nomenclature

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Alanine scanning mutagenesis of CCR3 reveals that the three intracellular loops are essential for functional receptor expression

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus chemokine receptor gene US28 is transcribed in latently infected THP-1 monocytes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Cytomegalovirus seropositivity and C-reactive protein have independent and combined predictive value for mortality in patients with angiographically demonstrated coronary artery disease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Drug discovery: a historical perspective

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

International union of pharmacology. XXII. Nomenclature for chemokine receptors

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Deletion of the R78 G protein-coupled receptor gene from rat cytomegalovirus results in an attenuated, syncytium-inducing mutant strain.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Kinetics of transcription of human cytomegalovirus chemokine receptor US28 in different cell types

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Functional analysis of the human cytomegalovirus US28 gene by insertion mutagenesis with the green fluorescent protein gene.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infection

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Chemokines and leukocyte traffic

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Identification of the human cytomegalovirus G protein-coupled receptor homologue encoded by UL33 in infected cells and enveloped virus particles.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Human cytomegalovirus open reading frame US28 encodes a functional beta chemokine receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

The cytomegalovirus US28 protein binds multiple CC chemokines with high affinity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Cytomegalovirus antigen within human arterial smooth muscle cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Cytomegalovirus homologs of cellular G protein-coupled receptor genes are transcribed

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6116241

Cytomegalovirus and atherosclerosis

30 November 2018

1 reference

12 December 2020

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

12 December 2020

G protein-coupled receptor kinases

1 reference

12 December 2020

Selective recognition of the membrane-bound CX3C chemokine, fractalkine, by the human cytomegalovirus-encoded broad-spectrum receptor US28

1 reference

12 December 2020

Cytomegalovirus genome and the immediate-early antigen in cells of different layers of human aorta

1 reference

12 December 2020

The expression of the cytomegalovirus chemokine receptor homolog US28 sequesters biologically active CC chemokines and alters IL-8 production

1 reference

12 December 2020

Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer

1 reference

12 December 2020

Reactivation of human cytomegalovirus in dendritic cells

1 reference

12 December 2020

Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus

1 reference

12 December 2020

Human cytomegalovirus-encoded UL33 and UL78 heteromerize with host CCR5 and CXCR4 impairing their HIV coreceptor activity

1 reference

12 December 2020

Identifiers

DOI

10.3390/V10080445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127279%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference