The Role of Autoimmune Regulator (AIRE) in Peripheral Tolerance (Q58764531)

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24 April 2020

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22 December 2020

The Role of Autoimmune Regulator (AIRE) in Peripheral Tolerance (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30255105%20AND%20SRC:MED&resulttype=core&format=json

autoimmune polyendocrine syndrome

24 April 2020

main subject

immunology

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hemic and immune systems

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18 October 2019

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22 December 2020

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24 April 2020

Lu Chang

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Haiying Fu

3

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24 April 2020

Guangyu Sun

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24 April 2020

Wei Yang

5

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author name string

Lu Chang

2

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Haiying Fu

3

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Guangyu Sun

4

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language of work or name

English

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publication date

4 September 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30255105%20AND%20SRC:MED&resulttype=core&format=json

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22 December 2020

Journal of Immunology Research

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2018

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page(s)

3930750

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Creative Commons Attribution 4.0 International

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copyright license

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on focus list of Wikimedia project

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ScienceSource

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cites work

Twenty Years of AIRE.

1 reference

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Deficiency of autoimmune regulator impairs the immune tolerance effect of bone marrow-derived dendritic cells in mice.

30 November 2018

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Transplantation of Aire-overexpressing bone marrow-derived dendritic cells delays the onset of type 1 diabetes.

30 November 2018

1 reference

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Autoimmune Regulator Expression in DC2.4 Cells Regulates the NF-κB Signaling and Cytokine Expression of the Toll-Like Receptor 3 Pathway

30 November 2018

1 reference

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T follicular helper cells in space-time.

30 November 2018

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AIRE-mutations and autoimmune disease

30 November 2018

1 reference

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AIRE expands: new roles in immune tolerance and beyond.

30 November 2018

1 reference

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Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program.

30 November 2018

1 reference

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Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance

30 November 2018

1 reference

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AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment

30 November 2018

1 reference

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Macrophages overexpressing Aire induce CD4+Foxp3+ T cells

30 November 2018

1 reference

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Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance

30 November 2018

1 reference

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Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire).

30 November 2018

1 reference

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DNA-PKcs interacts with Aire and regulates the expression of toll-like receptors in RAW264.7 cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

30 November 2018

1 reference

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Overexpressing autoimmune regulator regulates the expression of toll-like receptors by interacting with their promoters in RAW264.7 cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

A leucine-rich repeat assembly approach for homology modeling of the human TLR5-10 and mouse TLR11-13 ectodomains

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

30 November 2018

1 reference

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Deletional tolerance mediated by extrathymic Aire-expressing cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Critical immunological pathways are downregulated in APECED patient dendritic cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Expression of AIRE in thymocytes and peripheral lymphocytes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Modulation of Aire regulates the expression of tissue-restricted antigens

30 November 2018

1 reference

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Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

30 November 2018

1 reference

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The cellular mechanism of Aire control of T cell tolerance.

30 November 2018

1 reference

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30 November 2018

1 reference

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Expression of tissue-specific autoantigens in the hematopoietic cells leads to activation-induced cell death of autoreactive T cells in the secondary lymphoid organs.

30 November 2018

1 reference

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APECED-causing mutations in AIRE reveal the functional domains of the protein

30 November 2018

1 reference

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A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues.

30 November 2018

1 reference

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Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting.

30 November 2018

1 reference

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Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

30 November 2018

1 reference

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Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6142728

RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30255105

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12 December 2020

based on heuristic

Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30255105

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2018/3930750

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30255105%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30255105%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

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