Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLD (Q59789588)

12 December 2020

Copper deficiency and cholesterol metabolism in the rat.

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12 December 2020

The mechanism of adenosine triphosphate depletion in the liver after a load of fructose. A kinetic study of liver adenylate deaminase

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12 December 2020

The influence of gender on developing copper deficiency and on free radical generation of rats fed a fructose diet

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12 December 2020

Mechanisms of fructose-induced hypertriglyceridaemia in the rat. Activation of hepatic pyruvate dehydrogenase through inhibition of pyruvate dehydrogenase kinase

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12 December 2020

Glutathione production in copper-deficient isolated rat hepatocytes

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12 December 2020

Inhibition of elevated hepatic glutathione abolishes copper deficiency cholesterolemia

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12 December 2020

The severity of copper deficiency can be ameliorated by deferoxamine

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12 December 2020

Changes in Cu,Zn-Superoxide Dismutase, Cytochrome c Oxidase, Glutathione Peroxidase and Glutathione Transferase Activities in Copper-Deficient Mice and Rats

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12 December 2020

Intestinal absorption of fructose in the rat.

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12 December 2020

Sexual differences in the expression of copper deficiency in rats

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12 December 2020

Liquid-chromatographic measurements of inosine, hypoxanthine, and xanthine in studies of fructose-induced degradation of adenine nucleotides in humans and rats

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12 December 2020

Tissue distribution and excretion of copper-67 intraperitoneally administered to rats fed fructose or starch

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12 December 2020

Female rats are protected against the fructose induced mortality of copper deficiency

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12 December 2020

Effect of fructose or starch on copper-67 absorption and excretion by the rat

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12 December 2020

Effects of different dietary carbohydrates on hepatic enzymes of copper-deficient rats

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12 December 2020

Indices of copper status in humans consuming a typical American diet containing either fructose or starch

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12 December 2020

Cytochrome oxidase repair during treatment of copper deficiency: relation to mitochondrial turnover

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12 December 2020

Enzymes of fructose metabolism in human liver

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12 December 2020

Copper deficiency in the rat. Effect on the ultrastructure of hepatocytes

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12 December 2020

Depletion of liver adenine nucleotides induced by D-fructose. Dose-dependence and specificity of the fructose effect

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12 December 2020

Glucose utilization by the polyol pathway in human erythrocytes

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12 December 2020

Liver Adenine Nucleotides: Fructose-Induced Depletion and Its Effect on Protein Synthesis

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12 December 2020

Effect of Copper Deficiency on Metabolism and Mortality in Rats Fed Sucrose or Starch Diets

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12 December 2020

Impairment of Glucose Tolerance in Copper-Deficient Rats: Dependency on the Type of Dietary Carbohydrate

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12 December 2020

Direct measurement of polyol pathway activity in the ocular lens

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12 December 2020

The interaction of type of dietary carbohydrates with copper deficiency

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12 December 2020

Effect of dietary carbohydrates and copper status on blood pressure of rats

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12 December 2020

The severity of copper deficiency in rats is determined by the type of dietary carbohydrate

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12 December 2020

Diamine oxidase (histaminase). A circulating marker for rat intestinal mucosal maturation and integrity

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12 December 2020

Impaired glucose tolerance in copper-deficient rats

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12 December 2020

The human requirement for copper. I. Healthy men fed conventional, American diets

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12 December 2020

Dietary induction of intestinal fructose absorption in weaning rats

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12 December 2020

Assessment of copper nutritional status

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12 December 2020

Pool size and concentration of plasma cholesterol are increased and tissue copper levels are reduced during early stages of copper deficiency in rats.

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12 December 2020

Intakes and food sources of fructose in the United States

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12 December 2020

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12 December 2020

Low dietary iron prevents free radical formation and heart pathology of copper-deficient rats fed fructose

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12 December 2020

Assessment of copper status: effect of age and gender on reference ranges in healthy adults

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12 December 2020

Dietary ferric vs. ferrous iron in copper-deficient rats fed fructose-based diets

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12 December 2020

Responses of insulin to oral glucose and fructose loads in marginally copper-deficient rats fed starch or fructose.

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12 December 2020

Allopurinol, an inhibitor of xanthine oxidase, reduces uric acid levels and modifies the signs associated with copper deficiency in rats fed fructose

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12 December 2020

Hepatic iron overload may contribute to hypertriglyceridemia and hypercholesterolemia in copper-deficient rats

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12 December 2020

Hepatic fatty acid synthase gene transcription is induced by a dietary copper deficiency

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12 December 2020

Lack of a recommended dietary allowance for copper may be hazardous to your health

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12 December 2020

Decrease of cytochrome c oxidase protein in heart mitochondria of copper-deficient rats

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12 December 2020

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

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12 December 2020

Dietary fructose but not starch is responsible for hyperlipidemia associated with copper deficiency in rats: effect of high-fat diet

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12 December 2020

Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux

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12 December 2020

Plasma diamine oxidase activity is greater in copper-adequate than copper-marginal or copper-deficient rats

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12 December 2020

Hepatic fructose-metabolizing enzymes and related metabolites: role of dietary copper and gender

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12 December 2020

Effects of dietary fructose on plasma lipids in healthy subjects

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12 December 2020

Copper deficiency induces hepatic fatty acid synthase gene transcription in rats by increasing the nuclear content of mature sterol regulatory element binding protein 1.

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12 December 2020

Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc

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12 December 2020

Effects of dietary galactose and fructose on rats fed diets marginal or adequate in copper for 9-21 months

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12 December 2020

A longitudinal investigation of aggregate oral intake of copper

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12 December 2020

Cytochrome c oxidase deficiency due to mutations in SCO2, encoding a mitochondrial copper-binding protein, is rescued by copper in human myoblasts

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12 December 2020

The immune system as a physiological indicator of marginal copper status?

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12 December 2020

Level of dietary iron, not type of dietary fat, is hyperlipidemic in copper-deficient rats

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12 December 2020

Fructose metabolizing enzymes in the rat liver and metabolic parameters: Interactions between dietary copper, type of carbohydrates, and gender

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12 December 2020

Iron and copper alter tight junction permeability in human intestinal Caco-2 cells by distinct mechanisms

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12 December 2020

Female rats are protected against fructose-induced changes in metabolism and blood pressure

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12 December 2020

Copper modulates the degradation of copper chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome.

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12 December 2020

High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation

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12 December 2020

Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity

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12 December 2020

Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.

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12 December 2020

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

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12 December 2020

Unexpected role of ceruloplasmin in intestinal iron absorption.

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12 December 2020

Intake of sugar-sweetened beverages and weight gain: a systematic review

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12 December 2020

Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function

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12 December 2020

A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans.

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12 December 2020

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12 December 2020

Plasma diamine oxidase: a biomarker of copper deficiency in the bovine

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12 December 2020

Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.

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12 December 2020

Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004.

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12 December 2020

Associations of dietary and serum copper with inflammation, oxidative stress, and metabolic variables in adults.

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12 December 2020

Tetrathiomolybdate protects against bile duct ligation-induced cholestatic liver injury and fibrosis

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12 December 2020

Markedly blunted metabolic effects of fructose in healthy young female subjects compared with male subjects.

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12 December 2020

Fructose consumption as a risk factor for non-alcoholic fatty liver disease

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12 December 2020

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin

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12 December 2020

Regulation of the fructose transporter GLUT5 in health and disease

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12 December 2020

Copper availability contributes to iron perturbations in human nonalcoholic fatty liver disease

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12 December 2020

Developmental reprogramming of rat GLUT5 requires glucocorticoid receptor translocation to the nucleus

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12 December 2020

Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes

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12 December 2020

Dietary fructose consumption among US children and adults: the Third National Health and Nutrition Examination Survey

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12 December 2020

Copper regulation of hypoxia-inducible factor-1 activity

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12 December 2020

Soft drink consumption linked with fatty liver in the absence of traditional risk factors

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12 December 2020

Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension

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12 December 2020

When metals compete: a case of copper-deficiency myeloneuropathy and anemia.

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12 December 2020

Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses.

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12 December 2020

Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis

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12 December 2020

Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme

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12 December 2020

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

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12 December 2020

National estimates of dietary fructose intake increased from 1977 to 2004 in the United States

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12 December 2020

Molecular mechanisms of copper homeostasis

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12 December 2020

Alternative periplasmic copper-resistance mechanisms in Gram negative bacteria.

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12 December 2020

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice.

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12 December 2020

Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin II. The denture cream is a primary source of excessive zinc

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12 December 2020

Response of gram-positive bacteria to copper stress.

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12 December 2020

Copper deficiency after gastric bypass surgery

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12 December 2020

New developments in the regulation of intestinal copper absorption

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12 December 2020

Metabolic effects of fructose and the worldwide increase in obesity.

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12 December 2020

Redox regulation of SCO protein function: controlling copper at a mitochondrial crossroad

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12 December 2020

Sugar-sweetened beverages and risk of obesity and type 2 diabetes: epidemiologic evidence

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12 December 2020

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet

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12 December 2020

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

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12 December 2020

Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and Cardiovascular Disease Risk

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12 December 2020

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

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12 December 2020

A role for low hepatic copper concentrations in nonalcoholic Fatty liver disease

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12 December 2020

Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs

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12 December 2020

Human copper transporters: mechanism, role in human diseases and therapeutic potential

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12 December 2020

Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet

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12 December 2020

High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

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12 December 2020

Heavy metal toxicity following apical and basolateral exposure in the human intestinal cell line Caco-2.

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12 December 2020

Both isoforms of ketohexokinase are dispensable for normal growth and development

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12 December 2020

Prevalence, gender, ethnic variations, and prognosis of NASH.

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12 December 2020

Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008.

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12 December 2020

Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States.

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12 December 2020

High fructose feeding induces copper deficiency in Sprague-Dawley rats: a novel mechanism for obesity related fatty liver

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12 December 2020

Copper deficiency exacerbates bile duct ligation-induced liver injury and fibrosis in rats

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12 December 2020

An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

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12 December 2020

Is the Western diet adequate in copper?

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12 December 2020

Role of fructose-containing sugars in the epidemics of obesity and metabolic syndrome

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12 December 2020

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study

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12 December 2020

Impact of copper limitation on expression and function of multicopper oxidases (ferroxidases)

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12 December 2020

Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice

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12 December 2020

Copper homeostasis at the host-pathogen interface

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12 December 2020

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes

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12 December 2020

Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD.

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12 December 2020

Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization

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12 December 2020

Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease

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12 December 2020

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

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12 December 2020

Fructose metabolism in humans - what isotopic tracer studies tell us.

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12 December 2020

Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988-1994 to 2007-2010.

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12 December 2020

The role of fructose transporters in diseases linked to excessive fructose intake

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12 December 2020

Levels of serum ceruloplasmin associate with pediatric nonalcoholic fatty liver disease.

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12 December 2020

Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity

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12 December 2020

Dietary fructose in nonalcoholic fatty liver disease

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12 December 2020

Modest fructose beverage intake causes liver injury and fat accumulation in marginal copper deficient rats

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12 December 2020

Rate and regulation of copper transport by human copper transporter 1 (hCTR1)

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12 December 2020

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

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12 December 2020

No difference between high-fructose and high-glucose diets on liver triacylglycerol or biochemistry in healthy overweight men.

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12 December 2020

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin

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12 December 2020

Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis

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12 December 2020

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

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12 December 2020

Glucose transporter-8 (GLUT8) mediates glucose intolerance and dyslipidemia in high-fructose diet-fed male mice

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12 December 2020

Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain

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12 December 2020

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

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12 December 2020

Impact of copper deficiency in humans

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12 December 2020

Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis

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12 December 2020

Structural and metabolic changes in Atp7b-/- mouse liver and potential for new interventions in Wilson's disease

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12 December 2020

How copper traverses cellular membranes through the mammalian copper transporter 1, Ctr1.

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12 December 2020

Gender and racial differences in nonalcoholic fatty liver disease

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12 December 2020

Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses

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12 December 2020

Fructose leads to hepatic steatosis in zebrafish that is reversed by mechanistic target of rapamycin (mTOR) inhibition.

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12 December 2020

Xanthine oxidase in non-alcoholic fatty liver disease and hyperuricemia: One stone hits two birds

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12 December 2020

Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations

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12 December 2020

Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal-copper, high-fructose diet in male rats

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12 December 2020

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function.

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12 December 2020

HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity.

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12 December 2020

Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease

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12 December 2020

Estimated Global, Regional, and National Disease Burdens Related to Sugar-Sweetened Beverage Consumption in 2010.

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12 December 2020

Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome

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12 December 2020

Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis

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12 December 2020

Elevated copper impairs hepatic nuclear receptor function in Wilson's disease

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12 December 2020

Fructose and Cardiometabolic Health: What the Evidence From Sugar-Sweetened Beverages Tells Us.

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12 December 2020

Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome

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12 December 2020

Sexual Dimorphism of Adipose and Hepatic Aquaglyceroporins in Health and Metabolic Disorders

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12 December 2020

Prevalence of Obesity Among Adults and Youth: United States, 2011-2014.

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12 December 2020

Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice

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12 December 2020

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes.

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12 December 2020

Sugar- and artificially sweetened beverages and intrahepatic fat: A randomized controlled trial.

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12 December 2020

JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Sugar

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12 December 2020

Copper Deficiency after Gastric Bypass for Morbid Obesity: a Systematic Review

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12 December 2020

Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53.

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12 December 2020

No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial

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12 December 2020

Low hepatic copper content and PNPLA3 polymorphism in non-alcoholic fatty liver disease in patients without metabolic syndrome

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12 December 2020

In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease

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12 December 2020

Effect of fructose consumption on insulin sensitivity in nondiabetic subjects: a systematic review and meta-analysis of diet-intervention trials.

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12 December 2020

Sugar-sweetened Beverage Consumption Among U.S. Youth, 2011-2014.

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12 December 2020

Sugar-sweetened Beverage Consumption Among U.S. Adults, 2011-2014.

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12 December 2020

The role of insufficient copper in lipid synthesis and fatty-liver disease

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12 December 2020

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

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12 December 2020

Sco2 deficient mice develop increased adiposity and insulin resistance.

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12 December 2020

Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2.

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12 December 2020

Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity.

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12 December 2020

Low Hepatic Tissue Copper in Pediatric Nonalcoholic Fatty Liver Disease.

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12 December 2020

Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease.

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12 December 2020

The mitochondrion: a central architect of copper homeostasis.

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12 December 2020

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.

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12 December 2020

Dietary Copper-Fructose Interactions Alter Gut Microbial Activity in Male Rats.

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12 December 2020

Non-Alcoholic Fatty Liver Disease and Nutritional Implications: Special Focus on Copper.

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12 December 2020

Fructose metabolism and metabolic disease.

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12 December 2020

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.

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12 December 2020

The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids.

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12 December 2020

The negative impact of sugar-sweetened beverages on children's health: an update of the literature.

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12 December 2020

Copper/MYC/CTR1 interplay: a dangerous relationship in hepatocellular carcinoma.

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12 December 2020

Fructose-containing caloric sweeteners as a cause of obesity and metabolic disorders

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12 December 2020

Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.

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12 December 2020

Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.

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12 December 2020

Risk factors for development of nonalcoholic fatty liver disease after pancreatoduodenectomy.

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12 December 2020

Low hair copper concentration is related to a high risk of nonalcoholic fatty liver disease in adults

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12 December 2020