montelwcast (Q417767)

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

2-[1-[[[(1R)-1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]thio]methyl]cyclopropyl]acetic acid ^Saesneg

19 Hydref 2016

stereoisomer of ^Saesneg

2 ffynonellau

inferred from InChIKey ^Saesneg

inferred from InChI ^Saesneg

(S)-montelukast ^Saesneg

1 ffynhonnell

inferred from InChI ^Saesneg

cis-montelukast ^Saesneg

1 ffynhonnell

inferred from InChI ^Saesneg

fformwla gemegol

C₃₅H₃₆ClNO₃S

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

SMILES

CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

isomeric SMILES ^Saesneg

CC(C)(C1=CC=CC=C1CC[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

defined daily dose ^Saesneg

10 milligram

dull gweini

gweini genau

1 ffynhonnell

https://www.whocc.no/atc_ddd_index/?code=R03DC03

cynhwysyn actif yn

Singulair ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

14 Chwefror 2018

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

seasonal allergic rhinitis ^Saesneg

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

2 Hydref 2018

llid y ffroenau

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

2 Hydref 2018

y ddanadfrech

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

dyddiad neu amser cychwyn

2 Hydref 2018

clefyd y gwair

20 Chwefror 1998

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/MHM278SD3E

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020829s069,020830s071,021409s047lbl.pdf

asthma

dyddiad neu amser cychwyn

20 Chwefror 1998

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/MHM278SD3E

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020829s069,020830s071,021409s047lbl.pdf

adweithia'n ffisegol gyda

Cysteinyl leukotriene receptor 1 ^Saesneg

rôl y pwnc

antagonist ^Saesneg

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

3340

17 Awst 2016

G protein-coupled receptor 17 ^Saesneg

rôl y pwnc

antagonist ^Saesneg

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

3340

17 Awst 2016

legal status (medicine) ^Saesneg

boxed warning ^Saesneg

1 ffynhonnell

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

categori beichiogrwydd Awstralia B1

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Saesneg)

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

categori beichiogrwydd Unol Daleithiau America B

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

LiverTox likelihood score ^Saesneg

LiverTox toxicity likelihood category B ^Saesneg

1 ffynhonnell

LiverTox ^Saesneg

8 Ebrill 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Montelukast

last update ^Saesneg

4 Mehefin 2019

rôl y pwnc

cyffuriau trin asthma

1 ffynhonnell

15 Mawrth 2018

leukotriene antagonists ^Saesneg

1 ffynhonnell

15 Mawrth 2018

cytochrome P-450 CYP1A2 inducers ^Saesneg

1 ffynhonnell

15 Mawrth 2018

Montelukast

0 ffynonellau

Identifiers

InChI

InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

158966-92-8

2 ffynonellau

Global Substance Registration System ^Saesneg

UNII ^Saesneg

MHM278SD3E

montelukast (Saesneg)

19 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

10 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=158966-92-8

ChemSpider ID ^Saesneg

4444507

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

4444507

Montelukast (Saesneg)

19 Tachwedd 2016

PubChem CID ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

montelukast (Saesneg)

19 Tachwedd 2016

InChIKey

InChIKey ^Saesneg

Reaxys registry number ^Saesneg

7896575

0 ffynonellau

ChEBI ID ^Saesneg

50730

mapping relation type ^Saesneg

exact match ^Saesneg

3 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL787

MONTELUKAST (Saesneg)

19 Tachwedd 2016

ChEBI release 2019-10-02 ^Saesneg

InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1

International Chemical Identifier ^Saesneg

InChI

ChEMBL ID ^Saesneg

CHEMBL787

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL787

MONTELUKAST (Saesneg)

19 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL4486

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

MONTELUKAST (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID9023334

2 ffynonellau

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

InChIKey

InChIKey ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID403334

0 ffynonellau

LiverTox ID ^Saesneg

Montelukast

0 ffynonellau

EC number ^Saesneg

605-168-4

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.115.927

27 Rhagfyr 2018

Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]- (Saesneg)

dyfyniad

CAS no.: 158966-92-8 (Saesneg)

ECHA Substance Infocard ID ^Saesneg

100.115.927

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.115.927

27 Rhagfyr 2018

Cyclopropaneacetic acid, 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]- (Saesneg)

dyfyniad

CAS no.: 158966-92-8 (Saesneg)

Cod yr ATC

R03DC03

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

00471