topotecan (Q419953)

https://ru.wikipedia.org/?oldid=99430861

inferred from InChIKey ^Saesneg

defnydd

cyffur meddygol

0 ffynonellau

adeiledd gemegol

Topotecan Structural Formula V.1.svg
600 × 486; 34 KB

1 ffynhonnell

mewnforiwyd o

Wicipedia Rwseg

Wikimedia import URL ^Saesneg

màs

421.164 uned Dalton

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

C₂₃H₂₃N₃O₅

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

isomeric SMILES ^Saesneg

CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

Evotopin ^Saesneg

1 ffynhonnell

EMEA/H/C/000124

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000124/human_med_000774.jsp

22 Mawrth 2017

Hycamtin ^Saesneg

1 ffynhonnell

RxNorm ^Saesneg

RxNorm ID ^Saesneg

203472

14 Chwefror 2018

Potactasol ^Saesneg

1 ffynhonnell

EMEA/H/C/002282

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002282/human_med_001407.jsp

22 Mawrth 2017

Topotecan Actavis ^Saesneg

1 ffynhonnell

EMEA/H/C/001031

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001031/human_med_001096.jsp

22 Mawrth 2017

Topotecan Hospira ^Saesneg

1 ffynhonnell

EMEA/H/C/001192

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001192/human_med_001348.jsp

22 Mawrth 2017

Topotecan Teva ^Saesneg

1 ffynhonnell

EMEA/H/C/001071

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/001071/human_med_001097.jsp

22 Mawrth 2017

World Health Organisation international non-proprietary name ^Saesneg

topotecan (Saesneg)

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

carsinoma ceirchgell ar yr ysgyfaint

topotecan (Saesneg)

19 Hydref 2016

1 ffynhonnell

NDF-RT ^Saesneg

neoplasm diniwed ar yr ysgyfaint

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

carsinoma di-gell-bychain

13 Rhagfyr 2016

1 ffynhonnell

NDF-RT ^Saesneg

13 Rhagfyr 2016

bronchus carcinoma ^Saesneg

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

2 Hydref 2018

neuroblastoma, susceptibility to ^Saesneg

1 ffynhonnell

Drug Indications Extracted from FAERS ^Saesneg

carsinoma cell bychain yr ysgyfaint

2 Hydref 2018

dyddiad neu amser cychwyn

27 Mai 1996

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/7M7YKX2N15

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020671s021lbl.pdf

ovarian carcinoma ^Saesneg

dyddiad neu amser cychwyn

27 Mai 1996

cadarnhawyd gan

Food and Drug Administration ^Saesneg

1 ffynhonnell

Inxight: Drugs Database ^Saesneg

2 Tachwedd 2018

https://drugs.ncats.io/drug/7M7YKX2N15

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020671s021lbl.pdf

legal status (medicine) ^Saesneg

boxed warning ^Saesneg

1 ffynhonnell

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

categori beichiogrwydd Awstralia D

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Saesneg)

categori beichiogrwydd

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

categori beichiogrwydd Unol Daleithiau America D

1 ffynhonnell

mewnforiwyd o

Wicipedia Saesneg

gwneuthurwr

Pfizer ^Saesneg

1 ffynhonnell

https://www.pfizer.com/products/product-list

rôl y pwnc

topoisomerase inhibitor ^Saesneg

1 ffynhonnell

NDF-RT ^Saesneg

5 Mawrth 2018

topoisomerase I inhibitor ^Saesneg

1 ffynhonnell

15 Mawrth 2018

0 ffynonellau

0 ffynonellau

Topotecan

0 ffynonellau

Identifiers

InChI

InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1

1 ffynhonnell

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

InChIKey ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

ChEBI release 2020-09-01 ^Saesneg

Rhif Cofrestru CAS

123948-87-8

2 ffynonellau

UNII ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

InChIKey ^Saesneg

CAS Common Chemistry ^Saesneg

8 Ebrill 2021

https://commonchemistry.cas.org/detail?cas_rn=123948-87-8

ChemSpider ID ^Saesneg

54705

1 ffynhonnell

ChemSpider ^Saesneg

ChemSpider ID ^Saesneg

54705

Topotecan (Saesneg)

18 Tachwedd 2016

PubChem CID ^Saesneg

2 ffynonellau

PubChem ^Saesneg

PubChem CID ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

InChIKey ^Saesneg

Reaxys registry number ^Saesneg

4279441

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

topotecan (Saesneg)

19 Hydref 2016

ChEBI ID ^Saesneg

mapping relation type ^Saesneg

exact match ^Saesneg

2 ffynonellau

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL84

TOPOTECAN (Saesneg)

18 Tachwedd 2016

InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1

International Chemical Identifier ^Saesneg

InChI

ChEMBL ID ^Saesneg

CHEMBL84

1 ffynhonnell

ChEMBL ^Saesneg

ChEMBL ID ^Saesneg

CHEMBL84

TOPOTECAN (Saesneg)

18 Tachwedd 2016

SureChEMBL ID ^Saesneg

SCHEMBL3836

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

UniChem compound ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

Hazardous Substances Data Bank ^Saesneg

28 Hydref 2019

Topotecan (Saesneg)

10 Mai 2021

DSSTox substance ID ^Saesneg

DTXSID3042685

2 ffynonellau

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Saesneg

InChIKey ^Saesneg

DSSTOX compound identifier ^Saesneg

DTXCID1022685

0 ffynonellau

NSC number ^Saesneg

641007

0 ffynonellau

EC number ^Saesneg

687-471-1

0 ffynonellau

ECHA Substance Infocard ID ^Saesneg

100.213.372

1 ffynhonnell

ECHA Substance Infocard database ^Saesneg

ECHA Substance Infocard ID ^Saesneg

100.213.372

27 Rhagfyr 2018

4-Ethyl-4,9-dihydroxy-10-[(dimethylamino)methyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (Saesneg)

dyfyniad

CAS no.: 123948-87-8 (Saesneg)

Cod yr ATC

L01XX17

1 ffynhonnell

Dynodwr Drugbank (Alberta)

DrugBank ^Saesneg

01030

dynodwr Llawlyfr Ffarmacoleg Ligand

Topotecan (Saesneg)

dyddiad cyhoeddi

17 Tachwedd 2015

7101

1 ffynhonnell

dynodwr Llawlyfr Ffarmacoleg Ligand

IUPHAR/BPS Guide to PHARMACOLOGY ^Saesneg

7101

topotecan (Saesneg)

18 Tachwedd 2016

Topotecan

0 ffynonellau

MeSH concept ID ^Saesneg

M0029340

0 ffynonellau

Cod MeSH

D03.132.151.850

0 ffynonellau

RxNorm ID ^Saesneg

57308

1 ffynhonnell

UNII ^Saesneg

topotecan (Saesneg)

Dynodwr Drugbank (Alberta)

18 Tachwedd 2016

DB01030

1 ffynhonnell

InChIKey ^Saesneg

dynodwr HMDB

HMDB0015164

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

KNApSAcK ID ^Saesneg

C00052420

2 ffynonellau

inferred from InChIKey ^Saesneg

InChIKey ^Saesneg

UNII ^Saesneg

2 ffynonellau

UNII ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

InChIKey ^Saesneg

MedlinePlus drug identifier ^Saesneg

0 ffynonellau

intravenous injection ^Saesneg

0 ffynonellau

1 ffynhonnell

UNII ^Saesneg

topotecan (Saesneg)

18 Tachwedd 2016

Probes And Drugs ID ^Saesneg

PD003417

0 ffynonellau

DrugCentral ID ^Saesneg

1 ffynhonnell

UniChem ^Saesneg

1 ffynhonnell

ChEBI ^Saesneg

ChEBI ID ^Saesneg

dynodwr Microsoft Academic

topotecan (Saesneg)

19 Hydref 2016

0 ffynonellau

DeCS ID ^Saesneg

0 ffynonellau

1 ffynhonnell

Freebase Data Dumps ^Saesneg

dyddiad cyhoeddi

28 Hydref 2013

2781209748

0 ffynonellau

2909001671

0 ffynonellau

OpenAlex ID ^Saesneg

1 ffynhonnell

OpenAlex ^Saesneg

26 Ionawr 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID ^Saesneg

1RR8

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1RR8

1RR8 (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1K4T

1K4T (Saesneg)

19 Hydref 2016

1 ffynhonnell

Protein Data Bank ^Saesneg

PDB structure ID ^Saesneg

1RRJ

1RRJ (Saesneg)

19 Hydref 2016

Römpp online ID ^Saesneg

1 ffynhonnell

UMLS CUI ^Saesneg

1 ffynhonnell

UNII ^Saesneg

topotecan (Saesneg)