X-ray repair cross complementing 1 (Q8042454)

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mammalian protein found in Homo sapiens
  • X-ray repair cross-complementing protein 1
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • XRCC1
  • DNA repair protein XRCC1
  • X-ray Repair Cross Complementing Protein 1
  • XRCC1 protein, human
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Language Label Description Also known as
English
X-ray repair cross complementing 1
mammalian protein found in Homo sapiens
  • X-ray repair cross-complementing protein 1
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • XRCC1
  • DNA repair protein XRCC1
  • X-ray Repair Cross Complementing Protein 1
  • XRCC1 protein, human

Statements

molecular function
protein binding
determination method or standard
IPI
19 references
retrieved
8 April 2019
stated in
Aprataxin, a novel protein that protects against genotoxic stress
GOA
curator
UniProt
UniProt protein ID
P18887
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
SIRT1 deacetylates APE1 and regulates cellular base excision repair
GOA
curator
UniProt
UniProt protein ID
P18887
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein
GOA
curator
UniProt
UniProt protein ID
P18887
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Characterization of the redox transition of the XRCC1 N-terminal domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human DNA polymerase iota protects cells against oxidative stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
The FHA domain of aprataxin interacts with the C-terminal region of XRCC1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
APLF promotes the assembly and activity of non-homologous end joining protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase   binding affinity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Aprataxin, a novel protein that protects against genotoxic stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
retrieved
8 April 2019
stated in
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18887
determination method or standard
IPI
cell component
biological process
Gene Atlas image
PBB GE XRCC1 203655 at fs.png
732 × 530; 12 KB
0 references

Identifiers

MeSH descriptor ID
C000619371
subject named as
XRCC1 protein, human
0 references
 
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