Solute carrier family 22 member 3 (Q21104718)

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mammalian protein found in Homo sapiens

EMT organic cation transporter 3
solute carrier family 22 (organic cation transporter), member 3
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
organic cation transporter 3
extraneuronal monoamine transporter
EMT
solute carrier family 22 member 3

Language	Label	Description	Also known as
English	Solute carrier family 22 member 3	mammalian protein found in Homo sapiens	EMT organic cation transporter 3 solute carrier family 22 (organic cation transporter), member 3 SLC22A3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 organic cation transporter 3 extraneuronal monoamine transporter EMT solute carrier family 22 member 3

Statements

1 reference

13 November 2019

UniProt protein ID

organic cation transport protein/SVOP

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75751

major facilitator superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75751

Organic Cation Transporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Major facilitator superfamily domain

1 reference

based on heuristic

inferred from protein domain or family

Sugar transporter, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

1 reference

9 May 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

toxin transmembrane transporter activity

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

transporter activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic cation transmembrane transporter activity

determination method

6 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

1 January 2018

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

1 January 2018

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

1 January 2018

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

1 January 2018

Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

organic anion transmembrane transporter activity

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

dopamine:sodium symporter activity

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic cation transmembrane transporter activity

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic cation transmembrane transporter activity

determination method

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

integral component of plasma membrane

determination method

1 reference

9 May 2019

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

plasma membrane

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

biological process

histamine transport

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

monoamine transport

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

histamine uptake

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

xenobiotic transmembrane transport

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

toxin transport

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic cation transport

determination method

4 references

8 April 2019

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

8 April 2019

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

regulation of appetite

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

transmembrane transport

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic anion transport

determination method

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75751&geneProductId=UniProtKB:O75751

determination method

dopamine transport

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

dopamine uptake

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

organic cation transport

determination method

5 references

9 May 2019

Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75751

determination method

major facilitator superfamily domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75751

sugar transporter, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75751

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000275300

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000275300

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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