Cadherin 1 (Q21171812)

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mammalian protein found in Homo sapiens
  • cell-CAM 120/80
  • epididymis secretory sperm binding protein
  • uvomorulin
  • E-cadherin 1
  • E-cadherin
  • cadherin 1, type 1, E-cadherin (epithelial)
  • epithelial cadherin
  • cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CDH1
  • cadherin 1, E-cadherin (epithelial)
  • CAM 120/80
  • CDH1 protein, human
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Language Label Description Also known as
English
Cadherin 1
mammalian protein found in Homo sapiens
  • cell-CAM 120/80
  • epididymis secretory sperm binding protein
  • uvomorulin
  • E-cadherin 1
  • E-cadherin
  • cadherin 1, type 1, E-cadherin (epithelial)
  • epithelial cadherin
  • cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CDH1
  • cadherin 1, E-cadherin (epithelial)
  • CAM 120/80
  • CDH1 protein, human

Statements

part of
cadherin-1
0 references
molecular function
protein binding
determination method
IPI
28 references
retrieved
8 April 2019
stated in
The CD46-Jagged1 interaction is critical for human TH1 immunity
GOA
curator
UniProt
UniProt protein ID
P12830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells
GOA
curator
UniProt
UniProt protein ID
P12830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Identification of a physiological E2 module for the human anaphase-promoting complex
GOA
curator
UniProt
UniProt protein ID
P12830
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Molecular basis of actin reorganization promoted by binding of enterohaemorrhagic Escherichia coli EspB to alpha-catenin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
E-cadherin phosphorylation by protein kinase D1/protein kinase C{mu} is associated with altered cellular aggregation and motility in prostate cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
retrieved
8 April 2019
stated in
Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
C513384
subject named as
CDH1 protein, human
0 references
PDB structure ID
 
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