Molecular Basis of Reduced Pyridoxine 5′-Phosphate Oxidase Catalytic Activity in Neonatal Epileptic Encephalopathy Disorder (Q27657441)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759001%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder (English)

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7 February 2020

0 references

1 reference

Martino Luigi di Salvo

2

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7 February 2020

Roberto Contestabile

4

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7 February 2020

1

Faik N Musayev

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7 February 2020

5

Mohini S Ghatge

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7 February 2020

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Martin K Safo

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7 February 2020

7

Verne Schirch

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7 February 2020

author name string

Mario A Saavedra

3

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7 February 2020

Alexina Haynes

6

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7 February 2020

language of work or name

English

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publication date

15 September 2009

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7 February 2020

number of pages

8

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Journal of Biological Chemistry

inferred from page(s)

published in

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7 February 2020

volume

284

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issue

45

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7 February 2020

page(s)

30949-30956

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Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase

7 February 2020

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Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase

20 March 2017

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X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution

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X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with FMN at 1.8 A resolution

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Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase

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Depression of serum pyridoxal levels in theophylline-related seizures

29 September 2017

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29 September 2017

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Neonatal epileptic encephalopathy

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PNPO deficiency: an under diagnosed inborn error of pyridoxine metabolism

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Pyridoxal 5'-phosphate may be curative in early-onset epileptic encephalopathy.

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27 November 2018

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ACTH therapy for infantile spasms: a combination therapy with high-dose pyridoxal phosphate and low-dose ACTH

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Association between PNPO and schizophrenia in the Japanese population

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Pyridoxal phosphate-dependent neonatal epileptic encephalopathy

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Identifiers

DOI

10.1074/JBC.M109.038372

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759001%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759001%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references