Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery (Q35120831)

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English	Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery	scientific article

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scholarly article

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Europe PubMed Central

6 August 2017

Attenuation of acute stroke injury in rat brain by minocycline promotes blood-brain barrier remodeling and alternative microglia/macrophage activation during recovery (English)

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Europe PubMed Central

6 August 2017

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1 reference

based on heuristic

inferred from title

blood–brain barrier

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Yirong Yang

1

1 reference

Europe PubMed Central

6 August 2017

Victor M Salayandia

2

1 reference

Europe PubMed Central

6 August 2017

Jeffrey F Thompson

3

1 reference

Europe PubMed Central

6 August 2017

Lisa Y Yang

4

1 reference

Europe PubMed Central

6 August 2017

Eduardo Y Estrada

5

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Europe PubMed Central

6 August 2017

Yi Yang

6

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Europe PubMed Central

6 August 2017

publication date

10 February 2015

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Europe PubMed Central

6 August 2017

Journal of Neuroinflammation

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Europe PubMed Central

6 August 2017

12

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Europe PubMed Central

6 August 2017

26

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Europe PubMed Central

6 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 January 2015

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4340283/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/s12974-015-0245-4

0 references

The relationship between serial [(18) F]PBR06 PET imaging of microglial activation and motor function following stroke in mice

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9 July 2018

Brain pericytes acquire a microglial phenotype after stroke

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Innate immune activation in the pathogenesis of a murine model of globoid cell leukodystrophy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Microglial responses after ischemic stroke and intracerebral hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Microglia and ischemic stroke: a double-edged sword

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Innate immunity in the CNS: redefining the relationship between the CNS and Its environment

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9 July 2018

Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Minocycline selectively inhibits M1 polarization of microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Noninvasive molecular imaging of neuroinflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Minocycline development for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

The immunology of stroke: from mechanisms to translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Multiple roles of metalloproteinases in neurological disorders

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Arterial spin labeling and dynamic susceptibility contrast CBF MRI in postischemic hyperperfusion, hypercapnia, and after mannitol injection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Alternative activation of macrophages: mechanism and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Heterogeneity of microglial activation in the innate immune response in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Extension of the thrombolytic time window with minocycline in experimental stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Repairing the human brain after stroke. II. Restorative therapies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

MMP-9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Partial volume effect compensation for improved reliability of quantitative blood-brain barrier permeability

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Transforming growth factor-beta1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Cerebral ischemia and reperfusion: the pathophysiologic concept as a basis for clinical therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Patlak plots of Gd-DTPA MRI data yield blood-brain transfer constants concordant with those of 14C-sucrose in areas of blood-brain opening

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4340283

9 July 2018

Inflammation and infection in clinical stroke

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9 July 2018

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

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Minocycline mitigates motor impairments and cortical neuronal loss induced by focal ischemia in rats chronically exposed to ethanol during adolescence.

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Increased apparent diffusion coefficients on MRI linked with matrix metalloproteinases and edema in white matter after bilateral carotid artery occlusion in rats.

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27 September 2018

Differential neuroprotective effects of a minocycline-based drug cocktail in transient and permanent focal cerebral ischemia.

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27 September 2018

Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemia

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27 September 2018

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

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27 September 2018

Delayed minocycline treatment reduces long-term functional deficits and histological injury in a rodent model of focal ischemia.

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27 September 2018

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

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27 September 2018

White matter damage on diffusion tensor imaging correlates with age-related cognitive decline.

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Dose-response effect of tetracyclines on cerebral matrix metalloproteinase-9 after vascular endothelial growth factor hyperstimulation

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Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: an investigation using green fluorescent protein transgenic bone marrow chimeric mice

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Dopamine receptor modulation of hypoxic-ischemic neuronal injury in striatum of newborn piglets.

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Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

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12 December 2020

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10.1186/S12974-015-0245-4

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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