Cancer and aging: the molecular pathways (Q43251364)

17 November 2017

Cancer and aging: the molecular pathways (English)

1 reference

17 November 2017

2

1 reference

17 November 2017

PierFrancesco Bassi

1

1 reference

17 November 2017

1 November 2009

1 reference

17 November 2017

1 reference

17 November 2017

27

1 reference

17 November 2017

6

1 reference

17 November 2017

620-627

1 reference

p53 mutant mice that display early ageing-associated phenotypes

17 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

An Age-Induced Switch to a Hyper-Recombinational State

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Oxidants, oxidative stress and the biology of ageing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Aging: a theory based on free radical and radiation chemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The free radical theory of aging matures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Cells discover fire: employing reactive oxygen species in development and consequences for aging.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Immunological confirmation of elevated levels of CuZn superoxide dismutase protein in an artificially selected long-lived strain of Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Aging and resistance to oxidative damage in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

High-quality life extension by the enzyme peptide methionine sulfoxide reductase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Relevance of oxidative stress to the limited replicative capacity of cultured human diploid cells: the limit of cumulative population doublings increases under low concentrations of oxygen and decreases in response to aminotriazole

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

ROS, stress-activated kinases and stress signaling in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The contribution of endogenous sources of DNA damage to the multiple mutations in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed rat-1 fibroblasts through the induction of a stress response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Cell transformation by the superoxide-generating oxidase Mox1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Genetic determinants of p53-induced apoptosis and growth arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Endogenous oxidative stress: relationship to aging, longevity and caloric restriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mitochondria damage checkpoint, aging, and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Levels of DNA damage are unaltered in mice overexpressing human catalase in nuclei

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Science of cancer and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Structure and function of telomeres

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Aging and cancer cell biology, 2008.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The telomere hypothesis of cellular aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Long lifespan in worms with long telomeric DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Measuring vertebrate telomeres: applications and limitations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Telomeres, telomerase and malignant transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I--effects of proliferative senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The role of p53 and pRB in apoptosis and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The tumor suppressor p53: cancer and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The serious search for an anti-aging pill.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Use of microarray biomarkers to identify longevity therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The role of insulin-like signalling in the regulation of ageing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

The genetics of human longevity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Premature aging in mice deficient in DNA repair and transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mechanisms for methylation-mediated gene silencing and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Aging: gene silencing or gene activation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

DNA hypomethylation leads to elevated mutation rates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Mutations of mitotic checkpoint genes in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Expression and mutational analyses of the human MAD2L1 gene in breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Self-renewal and differentiation capacity of young and aged stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Stem cells and ageing. The potential of stem cells to overcome age-related deteriorations of the body in regenerative medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

How stem cells age and why this makes us grow old.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Wnt signalling in stem cells and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

Role of oxidative stress in telomere length regulation and replicative senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.UROLONC.2009.07.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.UROLONC.2009.07.013

1 reference

17 November 2017

1 reference

PubMed ID

19879472