Potassium voltage-gated channel subfamily Q member 3 (Q6449562)

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mammalian protein found in Homo sapiens

potassium voltage-gated channel subfamily KQT member 3
potassium voltage-gated channel, KQT-like subfamily, member 3
voltage-gated potassium channel subunit Kv7.3
potassium channel, voltage-gated, subfamily Q, member 3
KCNQ3
KQT-like 3
potassium channel subunit alpha KvLQT3
potassium channel, voltage gated KQT-like subfamily Q, member 3

Language	Label	Description	Also known as
English	Potassium voltage-gated channel subfamily Q member 3	mammalian protein found in Homo sapiens	potassium voltage-gated channel subfamily KQT member 3 potassium voltage-gated channel, KQT-like subfamily, member 3 voltage-gated potassium channel subunit Kv7.3 potassium channel, voltage-gated, subfamily Q, member 3 KCNQ3 KQT-like 3 potassium channel subunit alpha KvLQT3 potassium channel, voltage gated KQT-like subfamily Q, member 3

Statements

1 reference

13 November 2019

UniProt protein ID

Potassium channel, voltage dependent, KCNQ3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43525

KCNQ potassium channel

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Potassium channel, voltage dependent, KCNQ, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin-G binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

ion channel activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

voltage-gated potassium channel activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

protein binding

determination method

1 reference

8 April 2019

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

delayed rectifier potassium channel activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

calmodulin binding

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

determination method

2 references

plasma membrane

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

voltage-gated potassium channel complex

determination method

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

voltage-gated potassium channel complex

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

axon initial segment

determination method

3 references

8 April 2019

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

biological process

membrane hyperpolarization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

regulation of ion transmembrane transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

transmembrane transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

chemical synaptic transmission

determination method

1 reference

8 April 2019

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

potassium ion transmembrane transport

determination method

4 references

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

16 July 2018

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43525&geneProductId=UniProtKB:O43525

determination method

potassium ion transmembrane transport

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43525

determination method

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

tetraethylammonium

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

object has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL821

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL41355

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL266510

Gene Atlas image

PBB GE KCNQ3 206573 at fs.png
732 × 530; 12 KB

0 references

Ion transport domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43525

Potassium channel, voltage dependent, KCNQ, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43525

Ankyrin-G binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O43525

Identifiers

MeSH descriptor ID

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000429799

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000429799

ENSP00000373648

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000373648

ENSP00000428790

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000428790

ENSP00000482510

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482510

ENSP00000491165

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000491165

ENSP00000491940

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000491940

ENSP00000492691

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492691

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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