Signaling by kinase domain mutants of KIT (Q100166422)

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9669933)

Language	Label	Description	Also known as
English	Signaling by kinase domain mutants of KIT	An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9669933)

Statements

instance of

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8 July 2022

Signaling by KIT in disease

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-9669933

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8 July 2022

Constitutive phosphorylation of kinase domain KIT mutants

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8 July 2022

Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

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8 July 2022

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

1 reference

8 July 2022

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

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8 July 2022

C-kit mutations in core binding factor leukemias

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8 July 2022

Activating mutations of c-kit at codon 816 confer drug resistance in human leukemia cells

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8 July 2022

Activating c-kit gene mutations in human germ cell tumors

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8 July 2022

KIT as an Oncogenic Driver in Melanoma: An Update on Clinical Development

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8 July 2022

Gastrointestinal stromal tumor (GIST) pathogenesis, familial GIST, and animal models

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8 July 2022

A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors

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8 July 2022

Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours

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8 July 2022

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

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8 July 2022

Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala

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8 July 2022

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

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8 July 2022

Secondary KIT mutations: the GIST of drug resistance and sensitivity

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8 July 2022

The role of small molecule Kit protein-tyrosine kinase inhibitors in the treatment of neoplastic disorders.

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8 July 2022

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

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8 July 2022

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

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8 July 2022

Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation.

1 reference

8 July 2022

Gastrointestinal stromal tumours: origin and molecular oncology.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

Signaling by kinase domain mutants of KIT (Q100166422)

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Signaling by kinase domain mutants of KIT (Q100166422)

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Wikiquote(0 entries)

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