Dystrophin, muscular dystrophy (Q14864296)

WW domain superfamily

1 reference

EF-hand domain pair

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Zinc finger, ZZ-type, protein family

1 reference

EF-hand domain, type 2, protein family

1 reference

EF-hand domain, type 1, protein family

1 reference

Calponin homology domain, protein family

1 reference

WW domain, protein family

1 reference

Actinin-type actin-binding domain, conserved site, protein family

1 reference

Spectrin repeat, protein family

1 reference

Spectrin/alpha-actinin, protein family

1 reference

Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family

1 reference

25 May 2022

1 reference

25 May 2022

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Association of aciculin with dystrophin and utrophin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Three-dimensional regulation of radial glial functions by Lis1-Nde1 and dystrophin glycoprotein complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

The extracellular matrix protein agrin promotes heart regeneration in mice.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Differential association of syntrophin pairs with the dystrophin complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

nitric-oxide synthase binding

1 reference

10 September 2018

Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

structural constituent of muscle

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

protein-containing complex binding

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

neuron projection terminus

cell component

1 reference

10 September 2018

Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

Association of aciculin with dystrophin and utrophin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

Association of aciculin with dystrophin and utrophin

cell-substrate junction

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

IDA

postsynaptic membrane

1 reference

10 September 2018

9 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Caveolin-3 deficiency causes muscle degeneration in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Developmental regulation of biglycan expression in muscle and tendon

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Association of aciculin with dystrophin and utrophin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

dystrophin-associated glycoprotein complex

IDA

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

10 September 2018

Association of aciculin with dystrophin and utrophin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

mitochondrial outer membrane

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

synaptic vesicle membrane

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

perinuclear region of cytoplasm

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

matrix side of mitochondrial inner membrane

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

protein-containing complex

1 reference

10 September 2018

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

cardiac muscle contraction

biological process

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion

1 reference

10 September 2018

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

Muscular dystrophy begins early in embryonic development deriving from stem cell loss and disrupted skeletal muscle formation

myotube cell development

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

negative regulation of peptidyl-serine phosphorylation

1 reference

10 September 2018

Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

response to muscle stretch

regulation of ryanodine-sensitive calcium-release channel activity

1 reference

10 September 2018

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of voltage-gated calcium channel activity

1 reference

10 September 2018

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of transcription, DNA-templated

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

establishment of glial blood-brain barrier

1 reference

10 September 2018

Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of membrane potential

1 reference

10 September 2018

Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

1 reference

10 September 2018

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

peptide biosynthetic process

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of skeletal muscle contraction

1 reference

10 September 2018

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

Characterization of ARC, apoptosis repressor interacting with CARD, in normal and dystrophin-deficient skeletal muscle

muscle organ development

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

neurotransmitter receptor metabolic process

1 reference

10 September 2018

Acetylcholine receptors in innervated muscles of dystrophic mdx mice degrade as after denervation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

positive regulation of cell-matrix adhesion

1 reference

10 September 2018

Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

skeletal muscle tissue development

1 reference

10 September 2018

Muscular dystrophy begins early in embryonic development deriving from stem cell loss and disrupted skeletal muscle formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

positive regulation of sodium ion transmembrane transporter activity

1 reference

10 September 2018

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

negative regulation of ERK1 and ERK2 cascade

1 reference

10 September 2018

Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

olfactory nerve structural organization

1 reference

10 September 2018

Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

establishment of blood-nerve barrier

1 reference

10 September 2018

Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

muscle cell cellular homeostasis

1 reference

10 September 2018

X chromosome-linked muscular dystrophy (mdx) in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of gene expression

1 reference

10 September 2018

A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

neuron projection morphogenesis

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

muscle cell differentiation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

response to denervation involved in regulation of muscle adaptation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

skeletal muscle tissue regeneration

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

positive regulation of cell population proliferation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

response to water deprivation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

cerebral cortex development

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

neuron differentiation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

negative regulation of neuron differentiation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

regulation of cell cycle

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11531&geneProductId=UniProtKB:P11531

has part(s)

Spectrin/alpha-actinin

1 reference

EF-hand domain, type 2

1 reference

WW domain

1 reference

EF-hand domain, type 1

1 reference

Calponin homology domain

1 reference

Spectrin repeat

1 reference

Zinc finger, ZZ-type

1 reference

Actinin-type actin-binding domain, conserved site

1 reference