Early growth response 1 (Q14864827)

Zinc finger C2H2-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

early growth response transcription factors

1 reference

based on heuristic

inferred from protein domain or family

Early growth response protein 1, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

DNA-binding transcription factor activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

1 reference

11 October 2018

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

RNA polymerase II transcription regulatory region sequence-specific DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

sequence-specific DNA binding

3 references

3 references

double-stranded methylated DNA binding

3 references

hemi-methylated DNA-binding

3 references

promoter-specific chromatin binding

3 references

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

DNA-binding transcription activator activity, RNA polymerase II-specific

6 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

11 October 2018

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

11 October 2018

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

double-stranded DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

transcription factor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

11 October 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

DNA-binding transcription factor activity, RNA polymerase II-specific

IBA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

8 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

24 April 2018

NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

regulation of apoptotic process

IBA

biological process

1 reference

14 February 2019

Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

cellular response to organic substance

1 reference

14 February 2019

Regulation of GATA-3 expression during CD4 lineage differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

Molecular mechanisms of cell and tissue interactions during early tooth development

BMP signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08046&geneProductId=UniProtKB:P08046

positive regulation of transcription, DNA-templated

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

EGR1 regulates hepatic clock gene amplitude by activating Per1 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Repression of Pax-2 by WT1 during normal kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

Differential Regulation of Early Growth Response Gene-1 Expression by Insulin and Glucose in Vascular Endothelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

Thymocyte development in early growth response gene 1-deficient mice

T cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

cellular response to gamma radiation

1 reference

14 February 2019

PTEN regulation by Akt-EGR1-ARF-PTEN axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

regulation of transcription from RNA polymerase II promoter in response to hypoxia

1 reference

14 February 2019

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

skeletal muscle cell differentiation

1 reference

14 February 2019

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

negative regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of transcription by RNA polymerase II

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

14 February 2019

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

regulation of progesterone biosynthetic process

1 reference

14 February 2019

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of hormone biosynthetic process

1 reference

14 February 2019

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

cellular response to interleukin-8

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of cell death

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of smooth muscle cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of neuron apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

regulation of long-term neuronal synaptic plasticity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

positive regulation of smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

cellular response to heparin

regulation of transcription, DNA-templated

ISS

2 references

1 reference

14 February 2019

Thymocyte development in early growth response gene 1-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

circadian regulation of gene expression

IBA

1 reference

14 February 2019

Mice Lacking EGR1 Have Impaired Clock Gene (BMAL1) Oscillation, Locomotor Activity, and Body Temperature.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

circadian temperature homeostasis

1 reference

14 February 2019

Mice Lacking EGR1 Have Impaired Clock Gene (BMAL1) Oscillation, Locomotor Activity, and Body Temperature.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08046

has part(s)

Zinc finger C2H2-type

1 reference

Early growth response protein 1, C-terminal

1 reference

Early growth response, N-terminal

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016