Follicle stimulating hormone receptor (Q14904776)

http://www.ebi.ac.uk/interpro/protein/P35378

membrane protein

1 reference

inferred from GOA cell component → membrane

Leucine-rich repeat N-terminal domain, protein family

1 reference

Gonadotropin hormone receptor, transmembrane domain, protein family

1 reference

GPCR, rhodopsin-like, 7TM, protein family

1 reference

BspA type Leucine rich repeat region, protein family

1 reference

G protein-coupled peptide receptor activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

G protein-coupled receptor activity

IBA

signal transducer activity

2 references

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

protein-hormone receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

follicle-stimulating hormone receptor activity

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

16 July 2018

Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

16 July 2018

Inhibitory role of prolactin in the downregulation of testicular follicle-stimulating hormone receptors in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

follicle-stimulating hormone receptor activity

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Inhibitory role of prolactin in the downregulation of testicular follicle-stimulating hormone receptors in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

integral component of membrane

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35378&geneProductId=UniProtKB:P35378

integral component of membrane

ISS

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

2 references

regulation of protein phosphorylation

1 reference

14 February 2019

Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

positive regulation of intracellular estrogen receptor signaling pathway

1 reference

14 February 2019

Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of MAPK cascade

1 reference

14 February 2019

Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

1 reference

14 February 2019

The menopausal mouse: a new neural paradigm of a distressing human condition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of platelet-derived growth factor receptor signaling pathway

1 reference

14 February 2019

Aberrant expression of PDGF ligands and receptors in the tumor prone ovary of follitropin receptor knockout (FORKO) mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

primary ovarian follicle growth

1 reference

14 February 2019

Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of intracellular estrogen receptor signaling pathway

Structural and functional modifications of sertoli cells in the testis of adult follicle-stimulating hormone receptor knockout mice

2 references

Sertoli cell development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice

ovulation cycle process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

activation of adenylate cyclase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

1 reference

14 February 2019

The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

phospholipase C-activating G protein-coupled receptor signaling pathway

1 reference

14 February 2019

Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of chromosome organization

1 reference

14 February 2019

Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of osteoclast differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

3 references

14 February 2019

Spermatogenesis and sertoli cell activity in mice lacking sertoli cell receptors for follicle-stimulating hormone and androgen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of systemic arterial blood pressure

1 reference

14 February 2019

Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of acetylcholine metabolic process

1 reference

14 February 2019

Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

ovarian follicle development

IGI

6 references

14 February 2019

Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Haploinsufficiency of the follicle-stimulating hormone receptor accelerates oocyte loss inducing early reproductive senescence and biological aging in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Ovarian pathology and high incidence of sex cord tumors in follitropin receptor knockout (FORKO) mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

basement membrane organization

1 reference

14 February 2019

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

cellular water homeostasis

1 reference

14 February 2019

Structural and functional modifications of sertoli cells in the testis of adult follicle-stimulating hormone receptor knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

regulation of hormone metabolic process

4 references

14 February 2019

Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

The menopausal mouse: a new neural paradigm of a distressing human condition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

neuron projection development

1 reference

14 February 2019

Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

Qualitative and quantitative decline in spermatogenesis of the follicle-stimulating hormone receptor knockout (FORKO) mouse

sperm DNA condensation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

negative regulation of bone resorption

follicle-stimulating hormone signaling pathway

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

Molecular cloning of the mouse follicle-stimulating hormone receptor complementary deoxyribonucleic acid: functional expression of alternatively spliced variants and receptor inactivation by a C566T transition in exon 7 of the coding sequence

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

adenylate cyclase-activating G protein-coupled receptor signaling pathway

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378

G protein-coupled receptor signaling pathway

hormone-mediated signaling pathway

ISO

3 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35378