Thyroid stimulating hormone receptor (Q14904943)

Thyrotropin receptor

1 reference

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

BspA type Leucine rich repeat region, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

G protein-coupled peptide receptor activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

G protein-coupled receptor activity

protein-hormone receptor activity

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

thyroid-stimulating hormone receptor activity

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

24 April 2018

The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

24 April 2018

Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

signaling receptor activity

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

thyroid-stimulating hormone receptor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

integral component of membrane

cell component

2 references

1 reference

14 February 2019

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

basolateral plasma membrane

IDA

3 references

intracellular anatomical structure

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

dopaminergic neuron differentiation

biological process

1 reference

14 February 2019

Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

Primary B cell development is impaired in mice with defects of the pituitary/thyroid axis

B cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

inner ear receptor cell development

1 reference

14 February 2019

Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

2 references

1 reference

24 April 2018

Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

activation of adenylate cyclase activity

IDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

adult locomotory behavior

1 reference

14 February 2019

Spontaneous circling behavior and dopamine neuron loss in a genetically hypothyroid mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

positive regulation of multicellular organism growth

1 reference

14 February 2019

Spontaneous circling behavior and dopamine neuron loss in a genetically hypothyroid mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

inner ear receptor cell stereocilium organization

1 reference

14 February 2019

Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

Distortion product otoacoustic emissions and outer hair cell defects in the hyt/hyt mutant mouse

cochlea morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

Spontaneous circling behavior and dopamine neuron loss in a genetically hypothyroid mouse

regulation of locomotion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

hormone-mediated signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

thyroid-stimulating hormone signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

cellular response to glycoprotein

positive regulation of cell population proliferation

ISS

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

adenylate cyclase-activating G protein-coupled receptor signaling pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47750

positive regulation of adenylate cyclase activity

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47750&geneProductId=UniProtKB:P47750

GPCR, rhodopsin-like, 7TM

has part(s)

1 reference

BspA type Leucine rich repeat region

1 reference