Paxillin (Q14906595)

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mammalian protein found in Mus musculus
  • uniprot:Q8VI36
  • Pxn
  • paxillin
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Language Label Description Also known as
English
Paxillin
mammalian protein found in Mus musculus
  • uniprot:Q8VI36
  • Pxn
  • paxillin

Statements

molecular function
protein binding
determination method
IPI
8 references
retrieved
9 May 2019
stated in
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
LIM kinase 2 is widely expressed in all tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
retrieved
9 May 2019
stated in
EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IPI
cell component
focal adhesion
determination method
IDA
TAS
IEA
ISO
13 references
retrieved
8 April 2019
stated in
Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
TAS
retrieved
8 April 2019
stated in
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VI36
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IEA
retrieved
8 April 2019
stated in
Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
LIM kinase 2 is widely expressed in all tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
Phosphoinositide 3-kinase p85beta regulates invadopodium formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
8 April 2019
stated in
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
focal adhesion
determination method
IBA
IDA
IEA
ISO
TAS
14 references
retrieved
9 May 2019
stated in
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
TAS
retrieved
9 May 2019
stated in
Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8VI36
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IEA
retrieved
9 May 2019
stated in
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
LIM kinase 2 is widely expressed in all tissues
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Phosphoinositide 3-kinase p85beta regulates invadopodium formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8VI36
determination method
IBA
biological process

Identifiers

 
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