V-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Q14906762)

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mammalian protein found in Mus musculus

N-myc proto-oncogene protein
Mycn
uniprot:P03966
neuroblastoma myc-related oncogene 1
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived

Language	Label	Description	Also known as
English	V-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived	mammalian protein found in Mus musculus	N-myc proto-oncogene protein Mycn uniprot:P03966 neuroblastoma myc-related oncogene 1 v-myc myelocytomatosis viral related oncogene, neuroblastoma derived

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Transcription regulator Myc

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P03966

Helix-loop-helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P03966

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transcription regulator Myc, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

DNA-binding transcription factor activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

protein binding

determination method or standard

1 reference

9 May 2019

Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

protein dimerization activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

determination method or standard

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

14 February 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

14 February 2019

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

determination method or standard

6 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

biological process

embryonic skeletal system morphogenesis

determination method or standard

1 reference

9 May 2019

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

negative regulation of reactive oxygen species metabolic process

determination method or standard

1 reference

9 May 2019

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

embryonic digit morphogenesis

determination method or standard

1 reference

9 May 2019

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

negative regulation of astrocyte differentiation

determination method or standard

1 reference

9 May 2019

Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of cell death

determination method or standard

1 reference

9 May 2019

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

regulation of inner ear auditory receptor cell differentiation

determination method or standard

1 reference

9 May 2019

N-Myc and L-Myc are essential for hair cell formation but not maintenance

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of mesenchymal cell proliferation

determination method or standard

1 reference

9 May 2019

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

branching morphogenesis of an epithelial tube

determination method or standard

1 reference

9 May 2019

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

cartilage condensation

determination method or standard

1 reference

9 May 2019

Activities of N-Myc in the developing limb link control of skeletal size with digit separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of cell population proliferation

determination method or standard

1 reference

9 May 2019

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

lung development

determination method or standard

1 reference

9 May 2019

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

3 references

27 March 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

27 March 2018

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

27 March 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

27 March 2018

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03966&geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of gene expression

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

negative regulation of gene expression

determination method or standard

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03966

determination method or standard

Transcription regulator Myc, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P03966

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P03966

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000045993

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000045993

ENSMUSP00000114225

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000114225

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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