Indoleamine 2,3-dioxygenase 1 (Q14907419)

http://www.ebi.ac.uk/interpro/protein/P28776

Indoleamine 2,3-dioxygenase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28776

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

2 references

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

oxidoreductase activity

1 reference

14 February 2019

indoleamine 2,3-dioxygenase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

tryptophan 2,3-dioxygenase activity

ISO

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

14 January 2019

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

14 January 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

indoleamine 2,3-dioxygenase activity

IBA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

7 November 2018

Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

7 November 2018

Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

smooth muscle contractile fiber

IDA

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

2 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

1 reference

14 February 2019

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

negative regulation of interleukin-10 production

TAS

1 reference

14 February 2019

Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

multicellular organismal response to stress

1 reference

14 February 2019

Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

positive regulation of interleukin-12 production

1 reference

14 February 2019

Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

immune system process

1 reference

14 February 2019

positive regulation of T cell tolerance induction

1 reference

14 February 2019

Prevention of allogeneic fetal rejection by tryptophan catabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

cytokine production involved in inflammatory response

1 reference

14 February 2019

Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

positive regulation of chronic inflammatory response

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

negative regulation of activated T cell proliferation

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

negative regulation of T cell apoptotic process

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

response to lipopolysaccharide

1 reference

14 February 2019

Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

negative regulation of T cell proliferation

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

positive regulation of apoptotic process

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

tryptophan catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

positive regulation of type 2 immune response

1 reference

14 February 2019

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury

inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

kynurenic acid biosynthetic process

1 reference

14 February 2019

Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

1 reference

14 February 2019

Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

tryptophan catabolic process to kynurenine

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

7 November 2018

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

7 November 2018

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28776&geneProductId=UniProtKB:P28776

tryptophan catabolic process to kynurenine

IDA

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776

'de novo' NAD biosynthetic process from tryptophan

IBA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28776