SREBF chaperone (Q14913792)

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mammalian protein found in Mus musculus

Scap
sterol regulatory element-binding protein cleavage-activating protein
Sreb cleavage-activating protein
uniprot:Q6GQT6
SREBP cleavage activating protein

Language	Label	Description	Also known as
English	SREBF chaperone	mammalian protein found in Mus musculus	Scap sterol regulatory element-binding protein cleavage-activating protein Sreb cleavage-activating protein uniprot:Q6GQT6 SREBP cleavage activating protein

Statements

1 reference

25 May 2022

UniProt protein ID

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Sterol regulatory element-binding protein cleavage-activating protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Sterol-sensing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

cholesterol binding

determination method

1 reference

14 February 2019

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

determination method

2 references

endoplasmic reticulum

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

Golgi apparatus

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

ER to Golgi transport vesicle membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

integral component of membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

cytoplasmic vesicle

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

endoplasmic reticulum membrane

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

14 February 2019

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

biological process

lipid metabolism

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

regulation of fatty acid biosynthetic process

determination method

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

regulation of cholesterol biosynthetic process

determination method

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

response to hypoxia

determination method

1 reference

14 February 2019

Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

steroid metabolic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

regulation of fatty acid metabolic process

determination method

1 reference

14 February 2019

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

response to insulin

determination method

1 reference

14 February 2019

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

immune response

determination method

1 reference

14 February 2019

Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

cellular lipid metabolic process

determination method

1 reference

14 February 2019

Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6GQT6

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Sterol-sensing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

WD40 repeat, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6GQT6

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000095953

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000095953

ENSMUSP00000142458

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142458

ENSMUSP00000142919

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142919

ENSMUSP00000143369

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143369

ENSMUSP00000143710

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000143710

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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