cytochrome P450 family 27 subfamily A member 1 (Q1499996)

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mammalian protein found in Homo sapiens

cytochrome P450 27
cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1
vitamin D(3) 25-hydroxylase
cytochrome P450, family 27, subfamily A, polypeptide 1
5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase
cytochrome P-450C27/25
5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase
CYP27A1
sterol 26-hydroxylase, mitochondrial
sterol 27-hydroxylase
5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
cholestanetriol 26-monooxygenase

Language	Label	Description	Also known as
English	cytochrome P450 family 27 subfamily A member 1	mammalian protein found in Homo sapiens	cytochrome P450 27 cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 vitamin D(3) 25-hydroxylase cytochrome P450, family 27, subfamily A, polypeptide 1 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase cytochrome P-450C27/25 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase CYP27A1 sterol 26-hydroxylase, mitochondrial sterol 27-hydroxylase 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase cholestanetriol 26-monooxygenase

Statements

1 reference

13 November 2019

UniProt protein ID

cytochrome P450 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02318

cytochrome P450, E-class, group I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02318

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

monooxygenase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

iron ion binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

oxidoreductase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

determination method

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

vitamin D3 25-hydroxylase activity

determination method

1 reference

8 April 2019

Metabolism of vitamin D by human microsomal CYP2R1.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

cholestanetriol 26-monooxygenase activity

determination method

1 reference

8 April 2019

Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

mitochondrial matrix

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

mitochondrial membranes

determination method

1 reference

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

mitochondrial inner membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

biological process

sterol metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

bile acid biosynthetic process

determination method

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

bile acid biosynthetic process

determination method

3 references

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

14 January 2019

Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

14 January 2019

Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

cholesterol catabolic process

determination method

1 reference

14 January 2019

Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02318&geneProductId=UniProtKB:Q02318

determination method

calcitriol biosynthetic process from calciol

determination method

1 reference

8 April 2019

Metabolism of vitamin D by human microsomal CYP2R1.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

lipid metabolism

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

steroid biosynthetic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

bile acid biosynthetic process

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

8 April 2019

Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

8 April 2019

Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

steroid metabolic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

cholesterol metabolic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02318

determination method

Gene Atlas image

PBB GE CYP27A1 203979 at fs.png
732 × 530; 11 KB

0 references

cytochrome P450, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02318

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000258415

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000258415

ENSP00000392671

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000392671

ENSP00000404945

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404945

PDB structure ID

1 reference

5 January 2016

http://www.uniprot.org/uniprot/Q02318.txt?version=162

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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