Polymerase (RNA) II (DNA directed) polypeptide A (Q15335024)

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mammalian protein found in Mus musculus

DNA-directed RNA polymerase II subunit A
DNA-directed RNA polymerase II subunit RPB1
RNA polymerase II subunit B1
DNA-directed RNA polymerase III largest subunit
Polr2a
RNA polymerase II 1

Language	Label	Description	Also known as
English	Polymerase (RNA) II (DNA directed) polypeptide A	mammalian protein found in Mus musculus	DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase II subunit RPB1 RNA polymerase II subunit B1 DNA-directed RNA polymerase III largest subunit Polr2a RNA polymerase II 1

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

RNA polymerase Rpb1, funnel domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 7 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 4, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase Rpb1, domain 5, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase Rpb1, domain 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase Rpb1, domain 6, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase Rpb1, domain 7, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase Rpb1, domain 3, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase, alpha subunit, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA polymerase II, heptapeptide repeat, eukaryotic, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

nucleotidyltransferase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

RNA polymerase II activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

protein binding

determination method

7 references

14 February 2019

Feedback regulation of transcriptional termination by the mammalian circadian clock PERIOD complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

The splicing factor SC35 has an active role in transcriptional elongation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

ubiquitin protein ligase binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

protein C-terminus binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

DNA-directed 5'-3' RNA polymerase activity

determination method

determination method

2 references

determination method

1 reference

14 February 2019

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

RNA polymerase II, core complex

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

determination method

6 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

Unique subcellular distribution of RPB1 with a phosphorylated C-terminal domain (CTD) in mouse oocytes during meiotic division and its relationship with chromosome separation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

biological process

response to organic cyclic compound

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

transcription, DNA-templated

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

cellular response to oxygen levels

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

transcription by RNA polymerase II

determination method

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08775

determination method

transcription by RNA polymerase II

determination method

RNA polymerase Rpb1, domain 4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase, alpha subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 5

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase Rpb1, domain 7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase II, heptapeptide repeat, eukaryotic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

RNA polymerase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08775

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000050771

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000050771

ENSMUSP00000071200

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000071200

Sitelinks

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Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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