GABRB2 (Q18025112)

GABRB2, a key player in neuropsychiatric disorders and beyond

gene substitution association with

schizophrenia

genome-wide association study

has effect

risk factor

6 references

Association of SNPs and haplotypes in GABAA receptor beta2 gene with schizophrenia

Positive association of the human GABA-A-receptor beta 2 subunit gene haplotype with schizophrenia in the Chinese Han population

GABRB2 Association with Schizophrenia: Commonalities and Differences Between Ethnic Groups and Clinical Subtypes

Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia

Analysis of GABRB2 association with schizophrenia in German population with DNA sequencing and one-label extension method for SNP genotyping.

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

Family-based association study of lithium-related and other candidate genes in bipolar disorder

GABRB2, a key player in neuropsychiatric disorders and beyond

alcoholism

genome-wide association study

EXP

has effect

risk factor

4 references

Genetical genomic determinants of alcohol consumption in rats and humans

Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population.

Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

Glutamatergic and GABAergic susceptibility loci for heroin and cocaine addiction in subjects of African and European ancestry

GABRB2, a key player in neuropsychiatric disorders and beyond

7 references

A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy

A novel variant in GABRB2 associated with intellectual disability and epilepsy.

Novel genetic causes for cerebral visual impairment

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study

Potential role of GABAA receptor subunit; GABRA6, GABRB2 and GABRR2 gene polymorphisms in epilepsy susceptibility and pharmacotherapy in North Indian population

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

Enrichment of mutations in chromatin regulators in people with Rett syndrome lacking mutations in MECP2.

GABRB2, a key player in neuropsychiatric disorders and beyond

frontotemporal dementia

2 references

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

Genome-wide association study identifies two loci influencing plasma neurofilament light levels.

GABRB2, a key player in neuropsychiatric disorders and beyond

chromosome

human chromosome 5

genomic assembly

1 reference

1 reference

161288429

1 reference

160715436

1 reference

161549044

1 reference

160976050

Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia.

1 reference

5q34

1 reference

15 May 2022

decreased expression in

2 references

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

GABRB2 in schizophrenia and bipolar disorder: disease association, gene expression and clinical correlations

GABRB2, a key player in neuropsychiatric disorders and beyond

major depressive disorder

2 references

Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients.

GABRB2, a key player in neuropsychiatric disorders and beyond

frontotemporal dementia

3 references

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Immune checkpoint inhibitors: recent progress and potential biomarkers

GABRB2, a key player in neuropsychiatric disorders and beyond

papillary thyroid cancer

IDA

2 references

GABRB2 plays an important role in the lymph node metastasis of papillary thyroid cancer.

GABRB2, a key player in neuropsychiatric disorders and beyond

altered regulation leads to

5 references

Imprinting in the schizophrenia candidate gene GABRB2 encoding GABAA receptor β2 subunit

Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders

Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders.

Genetic and epigenetic regulation on the transcription of GABRB2: Genotype-dependent hydroxymethylation and methylation alterations in schizophrenia.

GABRB2, a key player in neuropsychiatric disorders and beyond

3 references

Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders

Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders.

GABRB2, a key player in neuropsychiatric disorders and beyond

papillary thyroid cancer

EXP

2 references

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

GABRB2, a key player in neuropsychiatric disorders and beyond

HomoloGene ID

7327

1 reference

15 May 2022

PBB GE GABRB2 207352 s at fs.png
732 × 530; 12 KB

0 references

increased expression in

2 references

Circulating MicroRNA Expression Levels Associated With Internet Gaming Disorder.

GABRB2, a key player in neuropsychiatric disorders and beyond

papillary thyroid cancer

EXP

4 references

High Diagnostic Accuracy Based on CLDN10, HMGA2, and LAMB3 Transcripts in Papillary Thyroid Carcinoma.

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas

GABRB2 plays an important role in the lymph node metastasis of papillary thyroid cancer.

GABRB2, a key player in neuropsychiatric disorders and beyond

2 references

7327

https://omabrowser.org/oma/vps/P47870/

2 references

7327

https://omabrowser.org/oma/vps/P47870/

1 reference

7327

Drosophila melanogaster

1 reference

https://omabrowser.org/oma/vps/P47870/

Orthologous MAtrix

reference URL

expressed in

Brodmann area 23

1

1 reference

20 April 2022

endothelial cell

2

1 reference

20 April 2022

postcentral gyrus

3

1 reference

20 April 2022

middle temporal gyrus

4

1 reference

20 April 2022

entorhinal cortex

5

1 reference

20 April 2022

external globus pallidus

6

1 reference

20 April 2022

superior frontal gyrus

7

1 reference

20 April 2022

pons

8

1 reference

20 April 2022

cerebellar cortex

9

1 reference

20 April 2022

cerebellar hemisphere

10

1 reference

20 April 2022

http://identifiers.org/ncbigene/2561

exact match

1 reference

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers.org

reference URL

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Ensembl transcript ID

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

1 reference

15 May 2022

1 reference

15 May 2022

2 references

imported from Wikimedia project

Russian Wikipedia

Online Mendelian Inheritance in Man

19 August 2019

1 reference

inferred by common HGNC mappings on source and on Wikidata