HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation (Q21089617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19730691%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation (English)

1 reference

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6 February 2020

0 references

1

Bastien Mangeat

Bastien

Mangeat

1 reference

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6 February 2020

5

Jeremy Luban

Jeremy

Luban

1 reference

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6 February 2020

3

Martin

Lehmann

Martin Lehmann

1 reference

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6 February 2020

6

Vincent

Piguet

Vincent Piguet

1 reference

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6 February 2020

Gustavo Gers-Huber

2

Gustavo

Gers-Huber

1 reference

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6 February 2020

Madeleine Zufferey

series ordinal

4

author given names

Madeleine

author last names

Zufferey

1 reference

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6 February 2020

language of work or name

English

0 references

publication date

4 September 2009

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6 February 2020

1 reference

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6 February 2020

volume

5

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6 February 2020

page(s)

e1000574

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6 February 2020

issue

9

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Creative Commons Attribution 4.0 International

6 February 2020

copyright license

start time

4 September 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism

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Silencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulation

19 March 2017

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Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

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7 April 2017

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The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

7 April 2017

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Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking

7 April 2017

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Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion

12 September 2017

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12 September 2017

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Glycerol monolaurate prevents mucosal SIV transmission

12 September 2017

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12 September 2017

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Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif

12 September 2017

1 reference

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Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor

12 September 2017

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An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The transmembrane domain of BST-2 determines its sensitivity to down-modulation by human immunodeficiency virus type 1 Vpu.

27 September 2017

1 reference

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Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000574

Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000574

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000574

Cytosolic degradation of T-cell receptor alpha chains by the proteasome

21 January 2018

1 reference

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Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation

21 January 2018

1 reference

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HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000574

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19730691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

RASSF1C, an Isoform of the Tumor Suppressor RASSF1A, Promotes the Accumulation of β-Catenin by Interacting with βTrCP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19730691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1000574

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19730691%20AND%20SRC:MED&resulttype=core&format=json

release_vifi27ldo5f3ncr5roqh2626by

6 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vifi27ldo5f3ncr5roqh2626by

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19730691%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references