ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair (Q21090645)

10 August 2022

Brian W Sager

2

Brian W

Sager

1 reference

10 August 2022

Aparna Gorthi

3

Aparna

Gorthi

1 reference

10 August 2022

Sonal S Tonapi

4

Sonal S

Tonapi

1 reference

10 August 2022

Eric J Brown

5

Eric J

Brown

1 reference

10 August 2022

Alexander J R Bishop

6

Alexander J R

Bishop

1 reference

Creative Commons Attribution 4.0 International

10 August 2022

language of work or name

English

0 references

publication date

2014

0 references

published in

PLOS One

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volume

9

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issue

3

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page(s)

e91222

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copyright license

start time

27 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

19 March 2017

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Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

19 March 2017

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

19 March 2017

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XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

19 March 2017

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Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells

19 March 2017

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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

19 March 2017

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DNA double-strand break repair: from mechanistic understanding to cancer treatment

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A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

19 March 2017

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The mouse p (pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2), and melanosomal pH

19 March 2017

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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

19 March 2017

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Molecular basis of albinism: mutations and polymorphisms of pigmentation genes associated with albinism

19 March 2017

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ATR disruption leads to chromosomal fragmentation and early embryonic lethality

19 March 2017

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The DNA replication checkpoint response stabilizes stalled replication forks

19 March 2017

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ATR activates the S-M checkpoint during unperturbed growth to ensure sufficient replication prior to mitotic onset

7 April 2017

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ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

12 September 2017

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Induction of homologous recombination following in utero exposure to DNA-damaging agents.

12 September 2017

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Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse

12 September 2017

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Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination

12 September 2017

1 reference

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Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context

12 September 2017

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A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes

12 September 2017

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Dissection of a mouse eye for a whole mount of the retinal pigment epithelium

12 September 2017

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Mechanisms of dealing with DNA damage-induced replication problems

12 September 2017

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

12 September 2017

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Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases

12 September 2017

1 reference

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Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest

12 September 2017

1 reference

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Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

12 September 2017

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Fhit and CHK1 have opposing effects on homologous recombination repair

12 September 2017

1 reference

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Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

27 September 2017

1 reference

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Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway.

27 September 2017

1 reference

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ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3968013

Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation.

27 September 2017

1 reference

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Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair

27 September 2017

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Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice.

30 May 2018

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Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

ATR and H2AX cooperate in maintaining genome stability under replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

Assembly of the brainstem cochlear nuclear complex is revealed by intersectional and subtractive genetic fate maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

Susceptibility of proliferating cells to benzo[a]pyrene-induced homologous recombination in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

Site-specific somatic mutagenesis in the retinal pigment epithelium.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3968013

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

29 November 2018

1 reference

12 December 2020

Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development

1 reference

12 December 2020

Direct Molecular Identification of the Mouse Pink-Eyed Unstable Mutation by Genome Scanning

1 reference

12 December 2020

On the mechanism of UV and gamma-ray-induced intrachromosomal recombination in yeast cells synchronized in different stages of the cell cycle

1 reference

12 December 2020

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7

1 reference

12 December 2020

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0091222

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0091222

1 reference

ADS bibcode

2014PLoSO...991222B

0 references

1 reference

1 reference

1 reference