Why most published research findings are false (Q21092395)

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2005 essay written by John Ioannidis

• Why Most Published Research Findings Are False

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Language	Label	Description	Also known as
English	Why most published research findings are false	2005 essay written by John Ioannidis	Why Most Published Research Findings Are False

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

title

Why most published research findings are false (English)

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

main subject

data ethics

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based on heuristic

inferred from citation network

replication crisis

1 reference

based on heuristic

inferred from title

reproducibility

1 reference

based on heuristic

inferred from title

corrigendum / erratum

Correction: Why Most Published Research Findings Are False

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author

John Ioannidis

series ordinal

1

object named as

John P. A. Ioannidis

author given names

John P A

author last names

Ioannidis

1 reference

stated in

PubMed

PubMed ID

16060722

retrieved

15 August 2022

language of work or name

English

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publication date

30 August 2005

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

full work available at URL

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124

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published in

PLOS MEDICINE

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

volume

2

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

page(s)

e124

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

document file on Wikimedia Commons

Ioannidis (2005) Why Most Published Research Findings Are False.pdf
1,237 × 1,631, 6 pages; 250 KB

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issue

8

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

copyright license

Creative Commons Attribution 2.5 Generic

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copyright status

copyrighted

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cites work

Reporting of conflicts of interest in guidelines of preventive and therapeutic interventions

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

Sifting the evidence-what's wrong with significance tests?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

Searching for genetic determinants in the new millennium

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

Meta-analysis of Observational Studies in Epidemiology: A Proposal for Reporting

2 references

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

19 March 2017

Contradicted and initially stronger effects in highly cited clinical research

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

7 April 2017

Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

7 April 2017

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

7 April 2017

Replication validity of genetic association studies

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

7 April 2017

Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Better reporting of harms in randomized trials: an extension of the CONSORT statement

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Failing the public health--rofecoxib, Merck, and the FDA.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Genetic associations: false or true?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Problems of reporting genetic associations with complex outcomes

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Unpublished rating scales: a major source of bias in randomised controlled trials of treatments for schizophrenia

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

What do we mean by validating a prognostic model?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Scientific journals and their authors' financial interests: a pilot study

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Transfer of technology from statistical journals to the biomedical literature. Past trends and future predictions

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

12 September 2017

Clinical Trial Registration: A Statement from the International Committee of Medical Journal Editors

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Comparison of methods for estimating the number of true null hypotheses in multiplicity testing.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Two cheers for P-values?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Any casualties in the clash of randomised and observational evidence?

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Epidemiology faces its limits.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1182327

retrieved

29 November 2018

Microarrays and molecular research: noise discovery?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of cancer outcome with microarrays: a multiple random validation strategy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICH Harmonised Tripartite Guideline. Statistical principles for clinical trials. International Conference on Harmonisation E9 Expert Working Group

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why do we need some large, simple randomized trials?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rules of evidence for cancer molecular-marker discovery and validation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

When are observational studies as credible as randomised trials?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/16060722

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A STATISTICAL PARADOX

1 reference

stated in

Crossref

reference URL

https://api.crossref.org/works/10.1371%2FJOURNAL.PMED.0020124

retrieved

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

DOI

10.1371/JOURNAL.PMED.0020124

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

Google Knowledge Graph ID

/g/11j5kq7fnn

0 references

Google Scholar paper ID

15681017780418799273

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OpenCitations bibliographic resource ID

86951

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

86951

PMCID

1182327

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

PubMed ID

16060722

1 reference

stated in

Europe PubMed Central

PubMed ID

16060722

retrieved

4 July 2017

ResearchGate publication ID

7686290

0 references

 

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Wikipedia(2 entries)

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• enwiki Why Most Published Research Findings Are False
• frwiki Why Most Published Research Findings Are False

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