Autophagy related 4B cysteine peptidase (Q21097596)

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mammalian protein found in Homo sapiens

autophagy-related cysteine endopeptidase 1
AUT-like 1 cysteine endopeptidase
hAPG4B
autophagin-1
ATG4 autophagy related 4 homolog B
APG4 autophagy 4 homolog B
autophagy-related protein 4 homolog B
ATG4B
cysteine protease ATG4B

Language	Label	Description	Also known as
English	Autophagy related 4B cysteine peptidase	mammalian protein found in Homo sapiens	autophagy-related cysteine endopeptidase 1 AUT-like 1 cysteine endopeptidase hAPG4B autophagin-1 ATG4 autophagy related 4 homolog B APG4 autophagy 4 homolog B autophagy-related protein 4 homolog B ATG4B cysteine protease ATG4B

Statements

1 reference

13 November 2019

UniProt protein ID

Papain-like cysteine peptidase superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y4P1

Cysteine protease ATG4B, metazoa

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y4P1

transporter of unknown biochemical mechanism

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Autophagy-related Phagophore-formation Transporter

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

endopeptidase activity

determination method

1 reference

8 April 2019

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

protein binding

determination method

8 references

8 April 2019

HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

Network organization of the human autophagy system

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

A directed protein interaction network for investigating intracellular signal transduction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

Nix is a selective autophagy receptor for mitochondrial clearance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

A human protein-protein interaction network: a resource for annotating the proteome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

cysteine-type endopeptidase activity

determination method

3 references

determination method

2 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

biological process

determination method

4 references

1 January 2018

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

1 January 2018

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

protein transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

autophagy of nucleus

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

C-terminal protein lipidation

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

positive regulation of protein catabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

autophagy of mitochondrion

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

autophagosome assembly

determination method

1 reference

27 February 2018

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

8 April 2019

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

protein targeting to membrane

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

protein delipidation

determination method

1 reference

27 February 2018

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4P1&geneProductId=UniProtKB:Q9Y4P1

determination method

autophagosome assembly

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4P1

determination method

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000383964

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383964

ENSP00000384259

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384259

ENSP00000384661

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384661

ENSP00000344960

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000344960

ENSP00000383582

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383582

ENSP00000383583

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383583

ENSP00000390597

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000390597

ENSP00000400050

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400050

ENSP00000487133

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487133

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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