Chloride voltage-gated channel 5 (Q21100771)

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mammalian protein found in Homo sapiens

• chloride transporter ClC-5
• Chloride channel protein 5
• CLCN5
• H(+)/Cl(-) exchange transporter 5
• ClC-5
• voltage-gated chloride ion channel CLCN5
• chloride channel, voltage-sensitive 5

edit

Language	Label	Description	Also known as
English	Chloride voltage-gated channel 5	mammalian protein found in Homo sapiens	chloride transporter ClC-5 Chloride channel protein 5 CLCN5 H(+)/Cl(-) exchange transporter 5 ClC-5 voltage-gated chloride ion channel CLCN5 chloride channel, voltage-sensitive 5

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51795

part of

chloride channel, core

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51795

Chloride channel ClC-5

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51795

CBS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

Protein CLCN5 PDB 2j9l.png
855 × 944; 482 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51795

encoded by

CLCN5

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51795

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

ion channel activity

determination method or standard

IEA

1 reference

retrieved

17 October 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

ATP binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

chloride channel activity

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

A common molecular basis for three inherited kidney stone diseases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

TAS

antiporter activity

determination method or standard

IEA

TAS

2 references

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

TAS

retrieved

1 January 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

voltage-gated chloride channel activity

determination method or standard

IEA

IBA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

identical protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Nucleotide recognition by the cytoplasmic domain of the human chloride transporter ClC-5

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IPI

protein binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IPI

solute:proton antiporter activity

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

chloride ion binding

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

antiporter activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

cell component

integral component of membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

membrane

determination method or standard

IDA

IEA

4 references

retrieved

17 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

17 October 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

17 October 2017

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IDA

retrieved

17 October 2017

stated in

Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IDA

Golgi membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

apical part of cell

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IDA

integral component of plasma membrane

determination method or standard

TAS

1 reference

retrieved

17 October 2017

stated in

A common molecular basis for three inherited kidney stone diseases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

TAS

lysosomal membrane

determination method or standard

IDA

1 reference

retrieved

17 October 2017

stated in

Integral and associated lysosomal membrane proteins

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IDA

endosome membrane

determination method or standard

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

endosome

determination method or standard

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

Golgi apparatus

determination method or standard

IDA

IEA

2 references

retrieved

17 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

17 October 2017

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IDA

cytosol

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IDA

plasma membrane

determination method or standard

IDA

IEA

2 references

retrieved

17 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

17 October 2017

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IDA

lysosomal membrane

determination method or standard

HDA

1 reference

retrieved

8 April 2019

stated in

Integral and associated lysosomal membrane proteins

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

HDA

early endosome

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

Golgi apparatus

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

plasma membrane

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

integral component of plasma membrane

determination method or standard

IBA

TAS

2 references

retrieved

8 April 2019

stated in

A common molecular basis for three inherited kidney stone diseases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

TAS

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IBA

membrane

determination method or standard

HDA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

retrieved

8 April 2019

stated in

Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IDA

retrieved

8 April 2019

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

HDA

biological process

excretion

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

A common molecular basis for three inherited kidney stone diseases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

TAS

ion transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

ion transmembrane transport

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

TAS

regulation of anion transmembrane transport

determination method or standard

IEA

1 reference

retrieved

17 October 2017

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

chloride transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

chloride transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

transport

determination method or standard

IEA

TAS

2 references

retrieved

17 October 2017

stated in

A common molecular basis for three inherited kidney stone diseases

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

TAS

retrieved

17 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

P51795

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51795&geneProductId=UniProtKB:P51795

determination method or standard

IEA

proton transmembrane transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51795

determination method or standard

IEA

exact match

http://purl.uniprot.org/uniprot/P51795

1 reference

stated in

Identifiers.org

has part(s)

CBS domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P51795

Identifiers

RefSeq protein ID

NP_000075

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

NP_001121370

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

NP_001121371

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

NP_001259031

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

NP_001269092

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

XP_016884746

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

XP_016884747

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1184

UniProt protein ID

P51795

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P51795

Ensembl protein ID

ENSP00000304257

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000304257

ENSP00000365256

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000365256

ENSP00000365259

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000365259

ENSP00000365276

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000365276

ENSP00000476732

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000476732

ENSP00000496056

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496056

ENSP00000496353

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496353

ENSP00000496632

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496632

ENSP00000495122

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000495122

Freebase ID

/m/03cwnml

0 references

Microsoft Academic ID

2780506506

0 references

PDB structure ID

2J9L

1 reference

stated in

UniProt

UniProt protein ID

P51795

retrieved

9 August 2016

language of work or name

English

2JA3

1 reference

stated in

UniProt

UniProt protein ID

P51795

retrieved

9 August 2016

language of work or name

English

Transporter Classification Database ID

2.A.49.2.2

1 reference

UniProt protein ID

P51795

 

Sitelinks

Wikipedia(6 entries)

edit

• bswiki CLCN5
• cywiki CLCN5
• dewiki Protonen-Chlorid-Austauscher 5
• enwiki CLCN5
• ruwiki Хлоридный канал 5
• ukwiki CLCN5

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21100771&oldid=2022914707"