C-type lectin domain family 4 member M (Q21100841)

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mammalian protein found in Homo sapiens

CLEC4M
L-SIGN
liver/lymph node-specific ICAM-3 grabbing non-integrin
CD299 antigen
CD209 antigen-like protein 1
dendritic cell-specific ICAM-3-grabbing non-integrin 2
DC-SIGNR
DC-SIGN2
mannose binding C-type lectin DC-SIGNR
DC-SIGN-related protein
Liver/lymph node-specific ICAM-3-grabbing non-integrin

Language	Label	Description	Also known as
English	C-type lectin domain family 4 member M	mammalian protein found in Homo sapiens	CLEC4M L-SIGN liver/lymph node-specific ICAM-3 grabbing non-integrin CD299 antigen CD209 antigen-like protein 1 dendritic cell-specific ICAM-3-grabbing non-integrin 2 DC-SIGNR DC-SIGN2 mannose binding C-type lectin DC-SIGNR DC-SIGN-related protein Liver/lymph node-specific ICAM-3-grabbing non-integrin

Statements

1 reference

13 November 2019

UniProt protein ID

C-type lectin-like/link domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H2X3

C-type lectin fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H2X3

C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CD209-like, C-type lectin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

C-type lectin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptide antigen binding

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

virus receptor activity

determination method

3 references

8 April 2019

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

8 April 2019

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

calcium-dependent protein binding

determination method

1 reference

8 April 2019

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

mannose binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

ICAM-3 receptor activity

determination method

1 reference

8 April 2019

A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

signaling receptor activity

determination method

1 reference

8 April 2019

A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

protein binding

determination method

1 reference

5 June 2018

Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9H2X3&geneProductId=UniProtKB:Q9H2X3

determination method

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

extracellular region

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

biological process

leukocyte cell-cell adhesion

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

cell-cell recognition

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

intracellular transport of virus

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

intracellular signal transduction

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

antigen processing and presentation

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

adaptive immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

viral genome replication

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

peptide antigen transport

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

modulation by virus of host process

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

innate immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

virion attachment to host cell

determination method

1 reference

8 April 2019

Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

viral entry into host cell

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9H2X3

determination method

C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H2X3

C-type lectin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H2X3

CD209-like, C-type lectin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9H2X3

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000248228

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000248228

ENSP00000316228

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000316228

ENSP00000351954

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000351954

ENSP00000470132

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470132

ENSP00000471125

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471125

ENSP00000471132

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471132

ENSP00000335228

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000335228

ENSP00000377680

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000377680

ENSP00000470137

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470137

ENSP00000470286

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470286

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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