FA complementation group M (Q21101297)

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mammalian protein found in Homo sapiens

• ATP-dependent RNA helicase FANCM
• Fanconi anemia group M protein
• FAAP250
• fanconi anemia-associated polypeptide of 250 kDa
• protein Hef ortholog
• Fanconi anemia complementation group M
• FANCM

edit

Language	Label	Description	Also known as
English	FA complementation group M	mammalian protein found in Homo sapiens	ATP-dependent RNA helicase FANCM Fanconi anemia group M protein FAAP250 fanconi anemia-associated polypeptide of 250 kDa protein Hef ortholog Fanconi anemia complementation group M FANCM

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYD8

image

FANCM structures sml.jpg
2,906 × 1,756; 589 KB

0 references

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYD8

encoded by

FANCM

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYD8

molecular function

DNA binding

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

nuclease activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

nucleotide binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

chromatin binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IDA

protein binding

determination method

IPI

3 references

retrieved

8 April 2019

stated in

MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IPI

retrieved

8 April 2019

stated in

Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IPI

ATP binding

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

hydrolase activity

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

helicase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

3'-5' DNA helicase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

cell component

FANCM-MHF complex

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IDA

Fanconi anaemia nuclear complex

determination method

IDA

2 references

retrieved

8 April 2019

stated in

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IDA

retrieved

8 April 2019

stated in

MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IDA

nucleus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

nucleoplasm

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IDA

biological process

resolution of meiotic recombination intermediates

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IMP

interstrand cross-link repair

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

TAS

replication fork processing

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IMP

nucleic acid phosphodiester bond hydrolysis

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

cellular response to DNA damage stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

DNA repair

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

DNA duplex unwinding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IEA

positive regulation of protein monoubiquitination

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.

GOA

curator

UniProt

UniProt protein ID

Q8IYD8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYD8

determination method

IMP

Identifiers

RefSeq protein ID

NP_001295062

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

NP_001295063

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

NP_065988

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_011535336

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_011535337

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_011535339

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_016877012

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_016877013

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_016877014

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_016877015

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

XP_016877016

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

57697

UniProt protein ID

Q8IYD8

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYD8

Ensembl protein ID

ENSP00000267430

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000267430

ENSP00000442493

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000442493

ENSP00000450596

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450596

ENSP00000450632

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450632

ENSP00000450797

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000450797

ENSP00000451846

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000451846

ENSP00000452033

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000452033

Freebase ID

/m/04lfptn

0 references

Microsoft Academic ID

2776431348

0 references

PDB structure ID

4BXO

1 reference

stated in

UniProt

UniProt protein ID

Q8IYD8

retrieved

9 August 2016

language of work or name

English

4DAY

1 reference

stated in

UniProt

UniProt protein ID

Q8IYD8

retrieved

9 August 2016

language of work or name

English

4DRB

1 reference

stated in

UniProt

UniProt protein ID

Q8IYD8

retrieved

9 August 2016

language of work or name

English

4E45

1 reference

stated in

UniProt

UniProt protein ID

Q8IYD8

retrieved

9 August 2016

language of work or name

English

4M6W

1 reference

stated in

UniProt

UniProt protein ID

Q8IYD8

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(4 entries)

edit

• bswiki FANCM
• enwiki FANCM
• ttwiki FANCM
• ukwiki FANCM

Wikibooks(0 entries)

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Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21101297&oldid=2022916270"