Ficolin 1 (Q21101391)

Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1

1 reference

Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fibrinogen, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

collagen triple helix repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

27 March 2018

Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00602&geneProductId=UniProtKB:O00602

3 references

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

8 April 2019

Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

8 April 2019

C-reactive protein collaborates with plasma lectins to boost immune response against bacteria

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

G protein-coupled receptor binding

IPI

1 reference

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

pattern recognition receptor activity

1 reference

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

serine-type endopeptidase activity

IMP

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00602&geneProductId=UniProtKB:O00602

carbohydrate derivative binding

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

extrinsic component of external side of plasma membrane

1 reference

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

secretory granule lumen

1 reference

8 April 2019

ficolin-1-rich granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

collagen-containing extracellular matrix

1 reference

8 April 2019

Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

complement activation, lectin pathway

HDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

complement activation

1 reference

8 April 2019

G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

recognition of apoptotic cell

IDA

1 reference

8 April 2019

Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

protein localization to cell surface

IDA

1 reference

8 April 2019

Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

cell surface pattern recognition receptor signaling pathway

IDA

1 reference

8 April 2019

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

IMP

immune system process

1 reference

8 April 2019

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00602&geneProductId=UniProtKB:O00602

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

innate immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00602

neutrophil degranulation

1 reference

8 April 2019

Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain

has part(s)

1 reference

Collagen triple helix repeat

1 reference

Fibrinogen, conserved site

1 reference

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016