GATA binding protein 3 (Q21101536)

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mammalian protein found in Homo sapiens
  • GATA-binding factor 3
  • GATA3 Transcription Factor
  • GATA3
  • trans-acting T-cell-specific transcription factor GATA-3
edit
Language Label Description Also known as
English
GATA binding protein 3
mammalian protein found in Homo sapiens
  • GATA-binding factor 3
  • GATA3 Transcription Factor
  • GATA3
  • trans-acting T-cell-specific transcription factor GATA-3

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IPI
DNA-binding transcription factor activity
determination method
IDA
IEA
IMP
TAS
9 references
retrieved
8 April 2019
stated in
Structure and expression of the human GATA3 gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
TAS
retrieved
8 April 2019
stated in
A T-cell specific TCR delta DNA binding protein is a member of the human GATA family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
TAS
retrieved
8 April 2019
stated in
GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
8 April 2019
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
DNA-binding transcription factor activity
determination method
IBA
IDA
IEA
IMP
TAS
10 references
retrieved
10 September 2018
stated in
Structure and expression of the human GATA3 gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
TAS
retrieved
10 September 2018
stated in
A T-cell specific TCR delta DNA binding protein is a member of the human GATA family
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
TAS
retrieved
10 September 2018
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
10 September 2018
stated in
GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
10 September 2018
stated in
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
10 September 2018
stated in
GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
10 September 2018
stated in
Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IBA
cell component
nucleus
determination method
IEA
IDA
8 references
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
21 June 2018
stated in
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
21 June 2018
stated in
GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
21 June 2018
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
21 June 2018
stated in
Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
21 June 2018
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23771&geneProductId=UniProtKB:P23771
determination method
IDA
nucleus
determination method
IBA
IDA
IEA
9 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
GOA
curator
LifeDB
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IBA
biological process
positive regulation of transcription, DNA-templated
determination method
ISS
IMP
IEA
IDA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
ISS
retrieved
8 April 2019
stated in
GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
8 April 2019
stated in
Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
ISS
IMP
IEA
IDA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
ISS
retrieved
8 April 2019
stated in
NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IEA
retrieved
8 April 2019
stated in
c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
Abundant expression of Kallikrein 1 gene in human keratinocytes was mediated by GATA3
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA
retrieved
8 April 2019
stated in
GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
GOA
curator
UniProt
UniProt protein ID
P23771
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23771
determination method
IDA

Identifiers

 
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