Tubulin beta 2B class IIb (Q21102151)

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mammalian protein found in Homo sapiens

tubulin, beta 2B
epididymis secretory sperm binding protein
tubulin beta-2B chain
TUBB2B
tubulin, beta polypeptide paralog
class IIb beta-tubulin
class II beta-tubulin isotype

Language	Label	Description	Also known as
English	Tubulin beta 2B class IIb	mammalian protein found in Homo sapiens	tubulin, beta 2B epididymis secretory sperm binding protein tubulin beta-2B chain TUBB2B tubulin, beta polypeptide paralog class IIb beta-tubulin class II beta-tubulin isotype

Statements

1 reference

13 November 2019

UniProt protein ID

Tubulin/FtsZ, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVA1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVA1

Tubulin/FtsZ, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVA1

Tubulin/FtsZ, GTPase domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVA1

Tubulin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9BVA1

Tubulin/FtsZ, 2-layer sandwich domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tubulin/FtsZ, GTPase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Beta tubulin, autoregulation binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tubulin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

structural constituent of cytoskeleton

determination method or standard

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

protein binding

determination method or standard

1 reference

9 May 2019

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

GTPase activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

protein heterodimerization activity

determination method or standard

3 references

9 May 2019

Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

De novo TUBB2B mutation causes fetal akinesia deformation sequence with microlissencephaly: An unusual presentation of tubulinopathy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

26 September 2017

PEX14 is required for microtubule-based peroxisome motility in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

1 reference

26 September 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

microtubule cytoskeleton

determination method or standard

determination method or standard

1 reference

9 May 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

determination method or standard

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

PEX14 is required for microtubule-based peroxisome motility in human cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

Schaffer collateral - CA1 synapse

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

biological process

cytoskeleton organization

determination method or standard

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BVA1&geneProductId=UniProtKB:Q9BVA1

determination method or standard

positive regulation of axon guidance

determination method or standard

1 reference

9 May 2019

An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

nervous system development

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

microtubule cytoskeleton organization

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

mitotic cell cycle

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

neuron migration

determination method or standard

3 references

9 May 2019

Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

microtubule-based process

determination method or standard

3 references

9 May 2019

De novo TUBB2B mutation causes fetal akinesia deformation sequence with microlissencephaly: An unusual presentation of tubulinopathy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

modulation of chemical synaptic transmission

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

embryonic brain development

determination method or standard

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BVA1

determination method or standard

physically interacts with

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL159

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201752

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1096380

vinblastine sulfate

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL378544

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL94657

vincristine sulfate

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL501867

object of statement has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL39541

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000259818

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000259818

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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