Glycine receptor alpha 1 (Q21103155)

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mammalian protein found in Homo sapiens
  • glycine receptor subunit alpha-1
  • glycine receptor strychnine-binding subunit
  • glycine receptor 48 kDa subunit
  • GLRA1
edit
Language Label Description Also known as
English
Glycine receptor alpha 1
mammalian protein found in Homo sapiens
  • glycine receptor subunit alpha-1
  • glycine receptor strychnine-binding subunit
  • glycine receptor 48 kDa subunit
  • GLRA1

Statements

molecular function
glycine binding
determination method
IDA
IEA
6 references
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
16 July 2018
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
The beta subunit determines the ligand binding properties of synaptic glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
extracellularly glycine-gated chloride channel activity
determination method
IDA
IGI
IEA
IMP
7 references
retrieved
16 July 2018
stated in
A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IMP
retrieved
16 July 2018
stated in
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IGI
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
16 July 2018
stated in
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
glycine binding
determination method
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
8 April 2019
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
The beta subunit determines the ligand binding properties of synaptic glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IBA
extracellularly glycine-gated chloride channel activity
determination method
IBA
IDA
IEA
IGI
IMP
8 references
retrieved
8 April 2019
stated in
A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IMP
retrieved
8 April 2019
stated in
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
8 April 2019
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IBA
cell component
integral component of plasma membrane
determination method
IDA
IEA
IMP
5 references
retrieved
16 July 2018
stated in
A novel recessive hyperekplexia allele GLRA1 (S231R): genotyping by MALDI-TOF mass spectrometry and functional characterisation as a determinant of cellular glycine receptor trafficking
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IMP
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
16 July 2018
stated in
Importance of Arg-219 for correct biogenesis of alpha 1 homooligomeric glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
16 July 2018
stated in
Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P23415&geneProductId=UniProtKB:P23415
determination method
IDA
integral component of plasma membrane
determination method
IBA
IDA
IEA
IMP
6 references
retrieved
8 April 2019
stated in
A novel recessive hyperekplexia allele GLRA1 (S231R): genotyping by MALDI-TOF mass spectrometry and functional characterisation as a determinant of cellular glycine receptor trafficking
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IEA
retrieved
8 April 2019
stated in
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Importance of Arg-219 for correct biogenesis of alpha 1 homooligomeric glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors
GOA
curator
UniProt
UniProt protein ID
P23415
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23415
determination method
IBA
biological process
physically interacts with

Identifiers

 
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